Epicentre’s Clinical Research Department fulfills the three basic missions of a research institution :
the production and dissemination of new knowledge through original research, exploitation of the results and strategic scientific planning;
training through supervision of students or participation in instruction;
expertise in conducting evaluations to strengthen internal capabilities or provide external services.
The department conducts research on medical treatment for major infectious diseases such as HIV infection, tuberculosis, and malaria, as well as neglected tropical diseases.
The research studies the appropriateness and efficacy of diagnostic and therapeutic options.
The results are primarily aimed at making informed clinical diagnostic and therapeutic decisions. Examples include diagnosis, new approaches to treatment, and monitoring of drug-resistant forms of tuberculosis, the efficacy of antiretroviral treatments in HIV-TB co-infection, long-term follow-up and evaluation of ARV access programs, monitoring of ARV side effects; efficacy of malaria treatments for pregnant women and children; simplified treatment of human African trypanosomiasis, diagnosis of Buruli ulcer, and strategies for controlling visceral leishmaniasis.