The Lancet Microbe. 2020 Jun 1;1(2):e56-8
Bacteriology
Laboratory
Publications
Cost and cost-effectiveness of a simplified treatment model with direct-acting antivirals for chronic hepatitis C in Cambodia.
Abstract
BACKGROUND & AIMS: In 2016, Médecins Sans Frontières established the first general population Hepatitis C virus (HCV) screening and treatment site in Cambodia, offering free direct acting antiviral (DAA) treatment.
Liver international : official journal of the International Association for the Study of the Liver 2020 May 31; doi: 10.1111/liv.14550. Epub 2020 05 31
Markov process
cost effectiveness
direct acting antiviral treatment
healthcare costs
hepatitis C
low income population
treatment costs
Serology for SARS-CoV-2: Apprehensions, opportunities, and the path forward.
Abstract
Serological testing for SARS-CoV-2 has enormous potential to contribute to COVID-19 pandemic response efforts. However, the required performance characteristics of antibody tests will critically depend on the use case (individual-level vs.
Science immunology 2020 05 19; 5(47); doi: 10.1126/sciimmunol.abc6347. Epub 2020 05 22
High sustained viral response rate in patients with hepatitis C using generic sofosbuvir and daclatasvir in Phnom Penh, Cambodia.
Abstract
Safe and efficacious pan-genotypic direct-acting antiviral (DAA) regimens, such as sofosbuvir and daclatasvir (SOF+DCV)facilitate simplified models of care for hepatitis C virus (HCV).
Journal of viral hepatitis 2020 May 02; doi: 10.1111/jvh.13311. Epub 2020 05 02
Cambodia
Daclatasvir
Hepatitis C
SVR12
Sofosbuvir
The Lancet. Infectious diseases 2020 May ; 20(5); 542. doi: 10.1016/S1473-3099(20)30265-6. Epub 2020 03 31
Quantification of glucose-6-phosphate dehydrogenase activity by spectrophotometry: A systematic review and meta-analysis.
Abstract
BACKGROUND: The radical cure of Plasmodium vivax and P. ovale requires treatment with primaquine or tafenoquine to clear dormant liver stages.
PLoS medicine 2020 May ; 17(5); e1003084. doi: 10.1371/journal.pmed.1003084. Epub 2020 05 14
Adherence and Population Pharmacokinetic Properties of Amodiaquine When Used for Seasonal Malaria Chemoprevention in African Children.
Abstract
Poor adherence to seasonal malaria chemoprevention (SMC) might affect the protective effectiveness of SMC.
Clinical pharmacology and therapeutics 2020 May ; 107(5); 1179-1188. doi: 10.1002/cpt.1707. Epub 2019 12 31
Suspected paracetamol overdose in Monrovia, Liberia: a matched case-control study.
Abstract
BACKGROUND: A cluster of cases of unexplained multi-organ failure was reported in children at Bardnesville Junction Hospital (BJH), Monrovia, Liberia.
BMC pediatrics 2020 Mar 30; 20(1); 139. doi: 10.1186/s12887-020-2008-3. Epub 2020 03 30
Liberia
Liver insufficiency
Paediatrics
Paracetamol
The risk of tuberculosis in children after close exposure: a systematic review and individual-participant meta-analysis.
Abstract
BACKGROUND: Tens of millions of children are exposed to Mycobacterium tuberculosis globally every year; however, there are no contemporary estimates of the risk of developing tuberculosis in exposed children.
Lancet (London, England) 2020 Mar 21; 395(10228); 973-984. doi: 10.1016/S0140-6736(20)30166-5. Epub 2020 03 22