Publications

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Safety of a heat-stable rotavirus vaccine among children in Niger: Data from a phase 3, randomized, double-blind, placebo-controlled trial.

Abstract

BACKGROUND: Rotavirus remains a major cause of diarrhea among children under 5 years of age. The efficacy of RotaSIIL, a pentavalent rotavirus vaccine, was shown in an event-driven trial in Niger.

Coldiron ME Guindo O Makarimi R Soumana I Matar Seck A Garba S Macher E Isanaka S Grais RF
Vaccine 2018 06 14; 36(25); 3674-3680. doi: 10.1016/j.vaccine.2018.05.023. Epub 2018 05 08
Adverse event Diarrhea Gastroenteritis Intussusception Niger Rotavirus infection Rotavirus vaccines Safety

Immunogenicity and Protection From a Single Dose of Internationally Available Killed Oral Cholera Vaccine: A Systematic Review and Metaanalysis.

Abstract

In addition to improved water supply and sanitation, the 2-dose killed oral cholera vaccine (OCV) is an important tool for the prevention and control of cholera.

Lopez AL Deen J Azman AS Luquero FJ Kanungo S Dutta S von Seidlein L Sack DA
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2018 Jun 01; 66(12); 1960-1971. doi: 10.1093/cid/cix1039. Epub 2018 11 13

Access to care for non-communicable diseases in Mosul, Iraq between 2014 and 2017: a rapid qualitative study.

Abstract

During June 2014 to April 2017, the population of Mosul, Iraq lived in a state of increasing isolation from the rest of Iraq due to the city's occupation by the Islamic State group.

Baxter LM Eldin MS Al Mohammed A Saim M Checchi F
Conflict and health 2018 ; 12 48. doi: 10.1186/s13031-018-0183-8. Epub 2018 12 29
Access to healthcare Conflict Diabetes Humanitarian Hypertension Iraq Non-communicable diseases War

Field evaluation of near point of care Cepheid GeneXpert HIV-1 Qual for early infant diagnosis.

Abstract

BACKGROUND: Access to point-of-care HIV testing shortens turn-around times, time to diagnosis and reduces loss to follow-up hence minimizing barriers to early linkage to care and treatment among HIV infected infants.

Opollo VS Nikuze A Ben-Farhat J Anyango E Humwa F Oyaro B Wanjala S Omwoyo W Majiwa M Akelo V Zeh C Maman D
PloS one 2018 ; 13(12); e0209778. doi: 10.1371/journal.pone.0209778. Epub 2018 12 27

Impact of "test and treat" recommendations on eligibility for antiretroviral treatment: Cross sectional population survey data from three high HIV prevalence countries.

Abstract

BACKGROUND: Latest WHO guidelines recommend starting HIV-positive individuals on antiretroviral therapy treatment (ART) regardless of CD4 count. We assessed additional impact of adopting new WHO guidelines.

Chihana ML Huerga H Van Cutsem G Ellman T Wanjala S Masiku C Szumilin E Etard JF Davies MA Maman D
PloS one 2018 ; 13(11); e0207656. doi: 10.1371/journal.pone.0207656. Epub 2018 11 26

Risk Factors for Vaginal Colonization and Relationship between Bacterial Vaginal Colonization and In-Hospital Outcomes in Women with Obstructed Labor in a Ugandan Regional Referral Hospital.

Abstract

Introduction: The proportion of women with severe maternal morbidity from obstructed labor is between 2 and 12% in resource-limited settings. Maternal vaginal colonization with group B streptococcus (GBS), , and spp.

Ngonzi J Bebell LM Bazira J Fajardo Y Nyehangane D Boum Y Nanjebe D Boatin A Kabakyenga J Jacquemyn Y Van Geertruyden JP Riley LE
International journal of microbiology 2018 ; 2018 6579139. doi: 10.1155/2018/6579139. Epub 2018 09 20

Antimicrobial treatment practices among Ugandan children with suspicion of central nervous system infection.

Abstract

Acute central nervous system (CNS) infections in children in sub-Saharan Africa are often fatal. Potential contributors include late presentation, limited diagnostic capacity and inadequate treatment.

Kemigisha E Nanjebe D Boum Y Langendorf C Aberrane S Nyehangane D Nackers F Mueller Y Charrel R Murphy RA Page AL Mwanga-Amumpaire J
PloS one 2018 ; 13(10); e0205316. doi: 10.1371/journal.pone.0205316. Epub 2018 10 09

HIV treatment is associated with a two-fold higher probability of raised triglycerides: Pooled Analyses in 21 023 individuals in sub-Saharan Africa.

Abstract

Background: Anti-retroviral therapy (ART) regimes for HIV are associated with raised levels of circulating triglycerides (TG) in western populations.

Ekoru K Young EH Dillon DG Gurdasani D Stehouwer N Faurholt-Jepsen D Levitt NS Crowther NJ Nyirenda M Njelekela MA Ramaiya K Nyan O Adewole OO Anastos K Compostella C Dave JA Fourie CM Friis H Kruger IM Longenecker CT Maher DP Mutimura E Ndhlovu CE Praygod G Pefura Yone EW Pujades-Rodriguez M Range N Sani MU Sanusi M Schutte AE Sliwa K Tien PC Vorster EH Walsh C Gareta D Mashili F Sobngwi E Adebamowo C Kamali A Seeley J Smeeth L Pillay D Motala AA Kaleebu P Sandhu MS
Global health, epidemiology and genomics 2018 ; 3 doi: 10.1017/gheg.2018.7. Epub 2018 05 08
Antiretroviral therapy Cardiovascular disease HIV Lipids Sub-Saharan Africa Triglycerides