Publications

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Efficacy of amodiaquine for uncomplicated Plasmodium falciparum malaria in Harper, Liberia.

Abstract

In the face of spreading chloroquine and sulfadoxine-pyrimethamine (SP) resistance, amodiaquine remains a cheap and efficacious alternative for treating uncomplicated Plasmodium falciparum malaria in many settings.

Checchi F Balkan S Vonhm BT Massaquoi M Biberson P Eldin de Pecoulas P Brasseur P Guthmann JP
Transactions of the Royal Society of Tropical Medicine and Hygiene ; 96(6); 670-3. doi: . Epub 2003 04 28

Mechanistic and structural basis for inhibition of thymidylate synthase ThyX.

Abstract

Nature has established two mechanistically and structurally unrelated families of thymidylate synthases that produce de novo thymidylate or dTMP, an essential DNA precursor.

Basta T Boum Y Briffotaux J Becker HF Lamarre-Jouenne I Lambry JC Skouloubris S Liebl U Graille M van Tilbeurgh H Myllykallio H
Open biology 2012 Oct ; 2(10); 120120. doi: 10.1098/rsob.120120. Epub 2013 07 12
antimicrobial compounds inhibitor screen naphthoquinone thymidylate synthase ThyX

Incidence, risk factors and causes of death in an HIV care programme with a large proportion of injecting drug users.

Abstract

OBJECTIVES: To identify factors influencing mortality in an HIV programme providing care to large numbers of injecting drug users (IDUs) and patients co-infected with hepatitis C (HCV).

Spillane H Nicholas S Tang Z Szumilin E Balkan S Pujades-Rodriguez M
Tropical medicine & international health : TM & IH 2012 Oct ; 17(10); 1255-63. doi: 10.1111/j.1365-3156.2012.03056.x. Epub 2012 08 05
HIV VIH antiretroviral therapy cohort study estudio de cohortes facteur de risque factores de riesgo injecting drug use mortalidad mortality mortalité risk factor terapia antirretroviral thérapie antirétrovirale usage de drogues injectables uso de drogas inyectables étude de cohorte

Sentinel site community surveillance of mortality and nutritional status in southwestern Central African Republic, 2010.

Abstract

BACKGROUND: During 2010, a community-based, sentinel site prospective surveillance system measured mortality, acute malnutrition prevalence, and the coverage of a Médecins Sans Frontières (MSF) intervention in four sous-préfectures of

Caleo GM Sy AP Balandine S Polonsky J Palma PP Grais RF Checchi F
Population health metrics 2012 Sep 04; 10(1); 18. doi: 10.1186/1478-7954-10-18. Epub 2012 09 04

Population pharmacokinetics of Artemether and dihydroartemisinin in pregnant women with uncomplicated Plasmodium falciparum malaria in Uganda.

Abstract

BACKGROUND: Malaria in pregnancy increases the risk of maternal anemia, abortion and low birth weight. Approximately 85.3 million pregnancies occur annually in areas with Plasmodium falciparum transmission.

Tarning J Kloprogge F Piola P Dhorda M Muwanga S Turyakira E Nuengchamnong N Nosten F Day NP White NJ Guerin PJ Lindegardh N
Malaria journal 2012 Aug 22; 11 293. doi: 10.1186/1475-2875-11-293. Epub 2012 08 22