Publications

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Artemether-lumefantrine to treat malaria in pregnancy is associated with reduced placental haemozoin deposition compared to quinine in a randomized controlled trial.

Abstract

BACKGROUND: Data on efficacy of artemisinin-based combination therapy (ACT) to treat Plasmodium falciparum during pregnancy in sub-Saharan Africa is scarce.

Muehlenbachs A Nabasumba C McGready R Turyakira E Tumwebaze B Dhorda M Nyehangane D Nalusaji A Nosten F Guerin PJ Piola P
Malaria journal 2012 May 03; 11 150. doi: 10.1186/1475-2875-11-150. Epub 2012 05 03

Predicting the clinical outcome of severe falciparum malaria in african children: findings from a large randomized trial.

Abstract

BACKGROUND: Data from the largest randomized, controlled trial for the treatment of children hospitalized with severe malaria were used to identify such predictors of a poor outcome from severe malaria.

von Seidlein L Olaosebikan R Hendriksen IC Lee SJ Adedoyin OT Agbenyega T Nguah SB Bojang K Deen JL Evans J Fanello CI Gomes E Pedro AJ Kahabuka C Karema C Kivaya E Maitland K Mokuolu OA Mtove G Mwanga-Amumpaire J Nadjm B Nansumba M Ngum WP Onyamboko MA Reyburn H Sakulthaew T Silamut K Tshefu AK Umulisa N Gesase S Day NP White NJ Dondorp AM
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2012 Apr ; 54(8); 1080-90. doi: 10.1093/cid/cis034. Epub 2012 03 12

High prevalence of multidrug-resistant tuberculosis, Swaziland, 2009-2010.

Abstract

In Africa, although emergence of multidrug-resistant (MDR) tuberculosis (TB) represents a serious threat in countries severely affected by the HIV epidemic, most countries lack drug-resistant TB data.

Sanchez-Padilla E Dlamini T Ascorra A Rüsch-Gerdes S Tefera ZD Calain P de la Tour R Jochims F Richter E Bonnet M
Emerging infectious diseases 2012 Jan ; 18(1); 29-37. doi: 10.3201/eid1801.110850. Epub 2012 05 15

Benefit of viral load testing for confirmation of immunological failure in HIV patients treated in rural Malawi.

Abstract

OBJECTIVE: Viral load testing is used in the HIV programme of Chiradzulu, Malawi, to confirm the diagnosis of immunological failure to prevent unnecessary switching to second-line therapy.

Kanapathipillai R McGuire M Mogha R Szumilin E Heinzelmann A Pujades-Rodríguez M
Tropical medicine & international health : TM & IH 2011 Dec ; 16(12); 1495-500. doi: 10.1111/j.1365-3156.2011.02874.x. Epub 2011 09 01