Pour rechercher une publication scientifique, insérez vos mots-clés en anglais.

Novel transdisciplinary methodology for cross-sectional analysis of snakebite epidemiology at national scale.


BACKGROUND: Worldwide, it is estimated that snakes bite 4.5-5.4 million people annually, 2.7 million of which are envenomed, and 81,000-138,000 die.

Auteurs: Alcoba G Ochoa C Babo Martins S Ruiz de Castañeda R Bolon I Wanda F Comte E Subedi M Shah B Ghimire A Gignoux E Luquero F Nkwescheu AS Sharma SK Chappuis F Ray N
Référence de l'article: PLoS neglected tropical diseases 2021 Feb 12; 15(2); e0009023. doi: 10.1371/journal.pntd.0009023. Epub 2021 02 12

Seroprevalence and risk factors of exposure to COVID-19 in homeless people in Paris, France: a cross-sectional study.


BACKGROUND: During the COVID-19 lockdown period from March 17 to May 11, 2020, French authorities in Paris and its suburbs relocated people experiencing recurrent homelessness to emergency shelters, hotels, and large venues.

Auteurs: Roederer T Mollo B Vincent C Nikolay B Llosa AE Nesbitt R Vanhomwegen J Rose T Goyard S Anna F Torre C Fourrey E Simons E Hennequin W Mills C Luquero FJ
Référence de l'article: The Lancet. Public health 2021 Feb 05; (); Array. doi: 10.1016/S2468-2667(21)00001-3. Epub 2021 02 05

Cost and cost-effectiveness of a real-world HCV treatment program among HIV-infected individuals in Myanmar.


INTRODUCTION: Over half of those hepatitis C virus (HCV)/HIV coinfected live in low-income and middle-income countries, and many remain undiagnosed or untreated.

Auteurs: Marquez LK Chaillon A Soe KP Johnson DC Zosso JM Incerti A Loarec A Nguyen A Walker JG Mafirakureva N Lo Re Iii V Wynn A McIntosh C Kiene SM Brodine S Garfein RS Vickerman P Martin NK
Référence de l'article: BMJ global health 2021 Feb ; 6(2); Array. doi: 10.1136/bmjgh-2020-004181. Epub 2021 02 25
HIV health economics viral hepatitis

Concomitant Treatment of Chronic Hepatitis C With Direct-Acting Antivirals and Multidrug-Resistant Tuberculosis Is Effective and Safe.


We assessed effectiveness and safety of concomitant chronic hepatitis C virus (HCV) treatment with direct-acting antivirals (DAAs) and multidrug-resistant tuberculosis (MDR-TB).

Auteurs: Melikyan N Huerga H Atshemyan H Kirakosyan O Sargsyants N Aydinyan T Saribekyan N Khachatryan N Oganezova I Falcao J Balkan S Hewison C
Référence de l'article: Open forum infectious diseases 2021 Feb ; 8(2); ofaa653. doi: 10.1093/ofid/ofaa653. Epub 2021 01 04
chronic hepatitis C direct-acting antiviral drugs multidrug-resistant tuberculosis sofosbuvir virus

Estimation of the correlates of protection of the rVSVΔG-ZEBOV-GP Zaire ebolavirus vaccine: a post-hoc analysis of data from phase 2/3 clinical trials.


BACKGROUND: Establishment of immune correlates of protection can provide a measurable criterion for assessing protection against infection or disease.

Auteurs: Rebecca F Grais Stephen B Kennedy Barbara E Mahon Sheri A Dubey ebecca J Grant-Klein R Ken Liu Jonathan Hartzel Beth-Ann Coller Carolee Welebob Mary E Hanson Jakub K Simon
Référence de l'article: Lancet Microbe 2021;2: e70–78;
Vaccination Ebola Clinical trial

Comparison of capillary versus venous blood for the diagnosis of Plasmodium falciparum malaria using rapid diagnostic tests.


We enrolled 250 febrile children in western Uganda to compare the results of malaria rapid diagnostic tests when using capillary versus venous blood. Participants were tested with four different RDT types.

Auteurs: Gorret AM Muhindo R Baguma E Ntaro M Mulogo EM Deutsch-Feldman M Juliano JJ Nyehangane D Boyce RM
Référence de l'article: The Journal of infectious diseases 2021 Jan 27; (); Array. doi: 10.1093/infdis/jiab032. Epub 2021 01 27
Diagnostic Test Malaria Plasmodium

Immunogenicity and safety of fractional doses of yellow fever vaccines: a randomised, double-blind, non-inferiority trial.


BACKGROUND: Stocks of yellow fever vaccine are insufficient to cover exceptional demands for outbreak response. Fractional dosing has shown efficacy, but evidence is limited to the 17DD substrain vaccine.

Auteurs: Juan-Giner A Kimathi D Grantz KH Hamaluba M Kazooba P Njuguna P Fall G Dia M Bob NS Monath TP Barrett AD Hombach J Mulogo EM Ampeire I Karanja HK Nyehangane D Mwanga-Amumpaire J Cummings DAT Bejon P Warimwe GM Grais RF
Référence de l'article: Lancet (London, England) 2021 Jan 09; 397(10269); 119-127. doi: 10.1016/S0140-6736(20)32520-4. Epub 2021 01 10

Outcomes of AIDS-associated Kaposi sarcoma in Mozambique after treatment with pegylated liposomal doxorubicin.


BACKGROUND: Kaposi's sarcoma (KS) is a common HIV-associated malignancy frequently associated with poor outcomes. It is the most frequently diagnosed cancer in major cities of Mozambique.

Auteurs: Coldiron ME Gutierrez Zamudio AG Manuel R Luciano G Rusch B Ciglenecki I Telnov A Grais RF Trellu LT Molfino L
Référence de l'article: Infectious agents and cancer 2021 Jan 07; 16(1); 2. doi: 10.1186/s13027-020-00341-4. Epub 2021 01 07
AIDS-related opportunistic infections Acquired immunodeficiency syndrome Doxorubicin Kaposi sarcoma Mozambique

Smartphone-Based Ophthalmic Imaging Compared to Spectral Domain Optical Coherence Tomography Assessment of Vertical Cup-to-Disc Ratio among Adults in Southwestern Uganda.


PRCIS: Using optical coherence tomography measurements as a reference standard for vertical cup-to-disc ratio (vCDR), a smartphone-based ophthalmic camera has a sensitivity of 67.7% and specificity of 96.7% to detect a vCDR greater tha

Auteurs: Idriss BR Tran TM Atwine D Chang RT Myung D Onyango J
Référence de l'article: Journal of glaucoma 2020 Dec 29; Publish Ahead of Print(); Array. doi: 10.1097/IJG.0000000000001779. Epub 2020 12 29