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HIV epidemic and cascade of care in 12 east African rural fishing communities: results from a population-based survey in Uganda.


BACKGROUND: In East Africa, fishing communities are considered most-at-risk populations for the acquisition of HIV.

Auteurs: Burgos-Soto J Ben Farhat J Alley I Ojuka P Mulogo E Kise-Sete T Bouhenia M Salumu L Mathela R Langendorf C Cohuet S Huerga H
Référence de l'article: BMC public health 2020 Jun 19; 20(1); 970. doi: 10.1186/s12889-020-09121-6. Epub 2020 06 19
Africa Antiretroviral therapy Cascade of care Communities Diagnosis Epidemic Fishing HIV Viral suppression

Systematic or Test-Guided Treatment for Tuberculosis in HIV-Infected Adults.


BACKGROUND: In regions with high burdens of tuberculosis and human immunodeficiency virus (HIV), many HIV-infected adults begin antiretroviral therapy (ART) when they are already severely immunocompromised.

Auteurs: Blanc FX Badje AD Bonnet M Gabillard D Messou E Muzoora C Samreth S Nguyen BD Borand L Domergue A Rapoud D Natukunda N Thai S Juchet S Eholié SP Lawn SD Domoua SK Anglaret X Laureillard D
Référence de l'article: The New England journal of medicine 2020 06 18; 382(25); 2397-2410. doi: 10.1056/NEJMoa1910708. Epub 2020 06 19

Exploring the relationships in prenatal weight gain, birth outcomes, and postnatal growth up to 2 Years of age using a longitudinal cohort in Niger.


OBJECTIVES: The first 1000 days of life, from conception until a child's second birthday, is a crucial period during which life-long foundations for good health, growth, and development are established.

Auteurs: Kohlmann K Guindo O Soumana I Grais R Isanaka S
Référence de l'article: Current Developments in Nutrition; Volume 4, Issue Supplement_2, June 2020; Page 1021,
Pregnancy Low birth weight Child Niger

Humoral and cellular immune response induced by rVSVΔG-ZEBOV-GP vaccine among frontline workers during the 2013-2016 West Africa Ebola outbreak in Guinea.


BACKGROUND: As part of a Phase III trial with the Ebola vaccine rVSVΔG-ZEBOV-GP in Guinea, we invited frontline workers (FLWs) to participate in a sub-study to provide additional information on the immunogenicity of the vaccine.

Auteurs: Boum Y Juan-Giner A Hitchings M Soumah A Strecker T Sadjo M Cuthbertson H Hayes P Tchaton M Jemmy JP Clarck C King D Faga EM Becker S Halis B Gunnstein N Carroll M Røttingen JA Kondé MK Doumbia M Henao-Restrepo AM Kieny MP Cisse M Draguez B Grais RF
Référence de l'article: Vaccine 2020 Jun 01; (); Array. doi: 10.1016/j.vaccine.2020.04.066. Epub 2020 06 01
Cellular response Ebola vaccine Frontline workers Humoral response Immunogenicity

To fast or not to fast: Lipid measurement and cardiovascular disease risk estimation in rural sub-Saharan Africa.


Background: Cardiovascular disease (CVD) morbidity and mortality are increasing in sub-Saharan Africa (sSA), highlighting the need for tools to enable CVD risk stratification in the region.

Auteurs: Yang IT Hemphill LC Kim JH Bibangambah P Sentongo R Kakuhire B Plutzky J Boum Y Tsai AC Okello S Siedner MJ
Référence de l'article: Journal of global health 2020 Jun ; 10(1); 010407. doi: 10.7189/jogh.10.010407. Epub 2020 04 15

Prevention of child wasting: Results of a Child Health & Nutrition Research Initiative (CHNRI) prioritisation exercise.


BACKGROUND: An estimated 49.5 million children under five years of age are wasted. There is a lack of robust studies on effective interventions to prevent wasting.

Auteurs: Frison S Angood C Khara T Bahwere P Black RE Briend A Connell N Fenn B Isanaka S James P Kerac M Mayberry A Myatt M Dolan C
Référence de l'article: PloS one 2020 ; 15(2); e0228151. doi: 10.1371/journal.pone.0228151. Epub 2020 02 12

Cost and cost-effectiveness of a simplified treatment model with direct-acting antivirals for chronic hepatitis C in Cambodia.


BACKGROUND & AIMS: In 2016, Médecins Sans Frontières established the first general population Hepatitis C virus (HCV) screening and treatment site in Cambodia, offering free direct acting antiviral (DAA) treatment.

Auteurs: Walker JG Mafirakureva N Iwamoto M Campbell L Kim CS Hastings RA Doussett JP Le Paih M Balkan S Marquardt T Maman D Loarec A Coast J Vickerman P
Référence de l'article: Liver international : official journal of the International Association for the Study of the Liver 2020 May 31; (); Array. doi: 10.1111/liv.14550. Epub 2020 05 31
Markov process cost effectiveness direct acting antiviral treatment healthcare costs hepatitis C low income population treatment costs