Publications

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The efficacy of chloroquine for the treatment of acute, uncomplicated, Plasmodium falciparum malaria in Laos.

Abstract

To assess the local efficacy of chloroquine for the treatment of acute, uncomplicated, Plasmodium falciparum malaria, children and adults from Sekong province (an area of Laos with a low intensity of transmission) were tested in a 28-day, in-vivo study

Guthmann JP Kasparian S Phetsouvanh R Nathan N Garcia M Phompida S Brockman A Gastellu M Legros D
Annals of tropical medicine and parasitology 2002 Sep ; 96(6); 553-7. doi: 10.1179/000349802125001654. Epub 2002 11 29

Konzo outbreak, in the south-west of the Democratic Republic of Congo, 1996.

Abstract

In August 1996, cases of poliomyelitis were reported in Kahemba zone, in the south-west of the Democratic Republic (DR) of Congo. The diagnosis was reviewed and charged to Konzo, a spastic paraparesis attributed to food cyanide intoxication.

Bonmarin I Nunga M Perea WA
Journal of tropical pediatrics 2002 08 ; 48(4); 234-8. doi: 10.1093/tropej/48.4.234. Epub 2002 09 26

Visceral leishmaniasis: current status of control, diagnosis, and treatment, and a proposed research and development agenda.

Abstract

Visceral leishmaniasis is common in less developed countries, with an estimated 500000 new cases each year. Because of the diversity of epidemiological situations, no single diagnosis, treatment, or control will be suitable for all.

Guerin PJ Olliaro P Sundar S Boelaert M Croft SL Desjeux P Wasunna MK Bryceson AD
The Lancet. Infectious diseases 2002 Aug ; 2(8); 494-501. doi: . Epub 2002 08 29

IgM quantification in the cerebrospinal fluid of sleeping sickness patients by a latex card agglutination test.

Abstract

An increased IgM concentration in cerebrospinal fluid (CSF), occurring as a consequence of massive intrathecal IgM synthesis, is a marker of interest for diagnosis of the meningo-encephalitic stage in human African trypanosomiasis.

Lejon V Legros D Richer M Ruiz JA Jamonneau V Truc P Doua F Djé N N'Siesi FX Bisser S Magnus E Wouters I Konings J Vervoort T Sultan F Büscher P
Tropical medicine & international health : TM & IH 2002 Aug ; 7(8); 685-92. doi: . Epub 2002 09 17

In vitro susceptibility of 120 strains of Neisseria gonorrhoeae isolated in Kyrghyzstan.

Abstract

BACKGROUND: The World Health Organization has established a worldwide program for gonococcal antimicrobial surveillance, but so far no data on gonococcal susceptibility in Central Asia are available.

Dorlencourt F Boireaux C Sednaoui P Danilenko NV Legros D
Sexually transmitted diseases 2002 Jul ; 29(7); 376-8. doi: . Epub 2002 11 05

Treatment of human African trypanosomiasis--present situation and needs for research and development.

Abstract

Human African trypanosomiasis re-emerged in the 1980s. However, little progress has been made in the treatment of this disease over the past decades. The first-line treatment for second-stage cases is melarsoprol, a toxic drug in use since 1949.

Legros D Ollivier G Gastellu-Etchegorry M Paquet C Burri C Jannin J Büscher P
The Lancet. Infectious diseases 2002 Jul ; 2(7); 437-40. doi: . Epub 2002 08 06