Helena Huerga

Adolescents and young adults are the most undiagnosed of HIV and virally unsuppressed in Eastern and Southern Africa: Pooled analyses from five population-based surveys.

Journal Reference: PLOS global public health 2023 ; 3(12); . doi: 10.1371/journal.pgph.0002398. Epub 2023 12 22

22.12.2023

Comparative effectiveness of adding delamanid to a multidrug-resistant tuberculosis regimen comprised of three drugs likely to be effective.

Journal Reference: PLOS global public health 2023 ; 3(4); . doi: 10.1371/journal.pgph.0000818. Epub 2023 04 28

28.04.2023

Evidence of HIV incidence reduction in young women, but not in adolescent girls, in KwaZulu-Natal, South Africa.

Journal Reference: IJID regions 2023 Sep ; 8; . doi: 10.1016/j.ijregi.2023.07.004. Epub 2023 07 13

01.09.2023

Novel FujiLAM assay to detect tuberculosis in HIV-positive ambulatory patients in four African countries: a diagnostic accuracy study.

Journal Reference: The Lancet. Global health 2023 Jan ; 11(1); . doi: 10.1016/S2214-109X(22)00463-6. Epub 2022 12 19

01.01.2023

Lots of considerations when evaluating the FujiLAM assay - Author's reply.

Journal Reference: The Lancet. Global health 2023 Apr ; 11(4); . doi: 10.1016/S2214-109X(23)00115-8. Epub 2023 03 16

01.04.2023

Increase in HIV viral suppression in KwaZulu-Natal, South Africa: Community-based cross sectional surveys 2018 and 2013. What remains to be done?

Journal Reference: PloS one 2022 ; 17(3); . doi: 10.1371/journal.pone.0265488. Epub 2022 03 24

01.06.2022

Safety and effectiveness outcomes from a 14-country cohort of patients with multi-drug resistant tuberculosis treated concomitantly with bedaquiline, delamanid and other second-line drugs.

Journal Reference: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2022 Mar 04; . doi: 10.1093/cid/ciac176. Epub 2022 03 04

04.03.2022

Safety of treatment regimens containing bedaquiline and delamanid in the endTB cohort.

Journal Reference: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2022 Jan 13; . doi: 10.1093/cid/ciac019. Epub 2022 01 13

13.01.2022

Higher risk sexual behaviour is associated with unawareness of HIV-positivity and lack of viral suppression - implications for Treatment as Prevention.

Journal Reference: Scientific reports 2017 Nov 23; 7(1); 16117. doi: 10.1038/s41598-017-16382-6. Epub 2017 11 23

23.11.2017

Population-level HIV incidence estimates using a combination of synthetic cohort and recency biomarker approaches in KwaZulu-Natal, South Africa.

Journal Reference: PloS one 2018 ; 13(9); e0203638. doi: 10.1371/journal.pone.0203638. Epub 2018 09 13

01.06.2018

Integrating hepatitis C treatment into multidrug-resistant TB care.

Journal Reference: Public health action 2022 Jun 21; 12(2); . doi: 10.5588/pha.22.0002. Epub 2022 06 23

21.06.2022

Incremental Yield of Including Determine-TB LAM Assay in Diagnostic Algorithms for Hospitalized and Ambulatory HIV-Positive Patients in Kenya.

Journal Reference: PloS one 2017 ; 12(1); e0170976. doi: 10.1371/journal.pone.0170976. Epub 2017 01 26

01.06.2017

The endTB observational study protocol: treatment of MDR-TB with bedaquiline or delamanid containing regimens.

Journal Reference: BMC infectious diseases 2019 Aug 20; 19(1); 733. doi: 10.1186/s12879-019-4378-4. Epub 2019 08 20

20.08.2019

Prevalence of TB and health-seeking behaviour.

Journal Reference: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2022 May 01; 26(5); . doi: 10.5588/ijtld.22.0001. Epub 2022 05 05

01.05.2022

Evidence of HIV incidence reduction in young women, but not in adolescent girls, in KwaZulu-Natal, South Africa.

Journal Reference: IJID regions 2023 Sep ; 8; . doi: 10.1016/j.ijregi.2023.07.004. Epub 2023 07 13

01.09.2023

Cost-effectiveness of diagnostic algorithms including lateral-flow urine lipoarabinomannan for HIV-positive patients with symptoms of tuberculosis.

Journal Reference: PloS one 2020 ; 15(1); e0227138. doi: 10.1371/journal.pone.0227138. Epub 2020 01 30

01.06.2020

Progress towards the UNAIDS 90-90-90 goals by age and gender in a rural area of KwaZulu-Natal, South Africa: a household-based community cross-sectional survey.

Journal Reference: BMC public health 2018 03 02; 18(1); 303. doi: 10.1186/s12889-018-5208-0. Epub 2018 03 02

02.03.2018

Urine lipoarabinomannan (LAM) testing for all HIV patients hospitalized in the medical wards identifies a large proportion of patients with tuberculosis at risk of death.

Journal Reference: Open Forum Infectious Diseases; ofaa639; https://doi.org/10.1093/ofid/ofaa639; 23 December 2020

23.12.2020

High prevalence of infection and low incidence of disease in child contacts of patients with drug-resistant tuberculosis: a prospective cohort study.

Journal Reference: Archives of disease in childhood 2018 Dec 06; . doi: 10.1136/archdischild-2018-315411. Epub 2018 12 06

06.12.2018

Feasibility and acceptability of using the novel urine-based FujiLAM test to detect tuberculosis: A multi-country mixed-methods study.

Journal Reference: Journal of clinical tuberculosis and other mycobacterial diseases 2022 May ; 27; . doi: 10.1016/j.jctube.2022.100316. Epub 2022 04 25

01.05.2022

Implementation and Operational Research: Feasibility of Using Tuberculin Skin Test Screening for Initiation of 36-Month Isoniazid Preventive Therapy in HIV-Infected Patients in Resource-Constrained Settings.

Journal Reference: Journal of acquired immune deficiency syndromes (1999) 2016 Apr 01; 71(4); e89-95. doi: 10.1097/QAI.0000000000000895. Epub 2016 07 06

01.04.2016

Mortality in the first six months among HIV-positive and HIV-negative patients empirically treated for tuberculosis.

Journal Reference: BMC infectious diseases 2019 Feb 11; 19(1); 132. doi: 10.1186/s12879-019-3775-z. Epub 2019 02 11

11.02.2019

Systematic, Point-of-Care Urine Lipoarabinomannan (Alere TB-LAM) Assay for Diagnosing Tuberculosis in Severely Immunocompromised HIV-Positive Ambulatory Patients.

Journal Reference: The American journal of tropical medicine and hygiene 2020 Jan 20; . doi: 10.4269/ajtmh.19-0493. Epub 2020 01 20

20.01.2020

Increase in HIV viral suppression in KwaZulu-Natal, South Africa: Community-based cross sectional surveys 2018 and 2013. What remains to be done?

Journal Reference: PloS one 2022 ; 17(3); . doi: 10.1371/journal.pone.0265488. Epub 2022 03 24

01.06.2022

A comparison of self-report and antiretroviral detection to inform estimates of antiretroviral therapy coverage, viral load suppression and HIV incidence in Kwazulu-Natal, South Africa.

Journal Reference: BMC infectious diseases 2017 09 29; 17(1); 653. doi: 10.1186/s12879-017-2740-y. Epub 2017 09 29

29.09.2017

Safety and effectiveness outcomes from a 14-country cohort of patients with multi-drug resistant tuberculosis treated concomitantly with bedaquiline, delamanid and other second-line drugs.

Journal Reference: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2022 Mar 04; . doi: 10.1093/cid/ciac176. Epub 2022 03 04

04.03.2022

Two-fold increase in the HIV viral load suppression rate along with decreased incidence over six years in Ndhiwa sub-county, Kenya.

Journal Reference: Tropical medicine & international health : TM & IH 2021 Oct 12; . doi: 10.1111/tmi.13688. Epub 2021 10 12

12.10.2021

HIV epidemic and cascade of care in 12 east African rural fishing communities: results from a population-based survey in Uganda.

Journal Reference: BMC public health 2020 Jun 19; 20(1); 970. doi: 10.1186/s12889-020-09121-6. Epub 2020 06 19

19.06.2020

Helena Huerga

Helena Huerga leads operational research studies with focus on infectious diseases and with particular interest on tuberculosis, HIV and viral hepatitis.

Her publications

Adolescents and young adults are the most undiagnosed of HIV and virally unsuppressed in Eastern and Southern Africa: Pooled analyses from five population-based surveys.

Comparative effectiveness of adding delamanid to a multidrug-resistant tuberculosis regimen comprised of three drugs likely to be effective.

Evidence of HIV incidence reduction in young women, but not in adolescent girls, in KwaZulu-Natal, South Africa.

Novel FujiLAM assay to detect tuberculosis in HIV-positive ambulatory patients in four African countries: a diagnostic accuracy study.

Lots of considerations when evaluating the FujiLAM assay - Author's reply.

Increase in HIV viral suppression in KwaZulu-Natal, South Africa: Community-based cross sectional surveys 2018 and 2013. What remains to be done?

Safety and effectiveness outcomes from a 14-country cohort of patients with multi-drug resistant tuberculosis treated concomitantly with bedaquiline, delamanid and other second-line drugs.

Safety of treatment regimens containing bedaquiline and delamanid in the endTB cohort.

Higher risk sexual behaviour is associated with unawareness of HIV-positivity and lack of viral suppression - implications for Treatment as Prevention.

Population-level HIV incidence estimates using a combination of synthetic cohort and recency biomarker approaches in KwaZulu-Natal, South Africa.

Integrating hepatitis C treatment into multidrug-resistant TB care.

Incremental Yield of Including Determine-TB LAM Assay in Diagnostic Algorithms for Hospitalized and Ambulatory HIV-Positive Patients in Kenya.

The endTB observational study protocol: treatment of MDR-TB with bedaquiline or delamanid containing regimens.

Prevalence of TB and health-seeking behaviour.

Evidence of HIV incidence reduction in young women, but not in adolescent girls, in KwaZulu-Natal, South Africa.

Cost-effectiveness of diagnostic algorithms including lateral-flow urine lipoarabinomannan for HIV-positive patients with symptoms of tuberculosis.

Progress towards the UNAIDS 90-90-90 goals by age and gender in a rural area of KwaZulu-Natal, South Africa: a household-based community cross-sectional survey.

Urine lipoarabinomannan (LAM) testing for all HIV patients hospitalized in the medical wards identifies a large proportion of patients with tuberculosis at risk of death.

High prevalence of infection and low incidence of disease in child contacts of patients with drug-resistant tuberculosis: a prospective cohort study.

Feasibility and acceptability of using the novel urine-based FujiLAM test to detect tuberculosis: A multi-country mixed-methods study.

Implementation and Operational Research: Feasibility of Using Tuberculin Skin Test Screening for Initiation of 36-Month Isoniazid Preventive Therapy in HIV-Infected Patients in Resource-Constrained Settings.

Mortality in the first six months among HIV-positive and HIV-negative patients empirically treated for tuberculosis.

Systematic, Point-of-Care Urine Lipoarabinomannan (Alere TB-LAM) Assay for Diagnosing Tuberculosis in Severely Immunocompromised HIV-Positive Ambulatory Patients.

Increase in HIV viral suppression in KwaZulu-Natal, South Africa: Community-based cross sectional surveys 2018 and 2013. What remains to be done?

A comparison of self-report and antiretroviral detection to inform estimates of antiretroviral therapy coverage, viral load suppression and HIV incidence in Kwazulu-Natal, South Africa.

Safety and effectiveness outcomes from a 14-country cohort of patients with multi-drug resistant tuberculosis treated concomitantly with bedaquiline, delamanid and other second-line drugs.

Two-fold increase in the HIV viral load suppression rate along with decreased incidence over six years in Ndhiwa sub-county, Kenya.

HIV epidemic and cascade of care in 12 east African rural fishing communities: results from a population-based survey in Uganda.