Helena Huerga

COVID-19, tuberculosis, and HIV triad: a prospective observational study in ambulatory patients in Kenya, Uganda, and South Africa.

Journal Reference: PLOS global public health 2025 ; 5(4); . doi: 10.1371/journal.pgph.0004471. Epub 2025 04 23

23.04.2025

Adolescents and young adults are the most undiagnosed of HIV and virally unsuppressed in Eastern and Southern Africa: Pooled analyses from five population-based surveys.

Journal Reference: PLOS global public health 2023 ; 3(12); . doi: 10.1371/journal.pgph.0002398. Epub 2023 12 22

22.12.2023

Comparative effectiveness of adding delamanid to a multidrug-resistant tuberculosis regimen comprised of three drugs likely to be effective.

Journal Reference: PLOS global public health 2023 ; 3(4); . doi: 10.1371/journal.pgph.0000818. Epub 2023 04 28

28.04.2023

Evidence of HIV incidence reduction in young women, but not in adolescent girls, in KwaZulu-Natal, South Africa.

Journal Reference: IJID regions 2023 Sep ; 8; . doi: 10.1016/j.ijregi.2023.07.004. Epub 2023 07 13

01.09.2023

Novel FujiLAM assay to detect tuberculosis in HIV-positive ambulatory patients in four African countries: a diagnostic accuracy study.

Journal Reference: The Lancet. Global health 2023 Jan ; 11(1); . doi: 10.1016/S2214-109X(22)00463-6. Epub 2022 12 19

01.01.2023

Lots of considerations when evaluating the FujiLAM assay - Author's reply.

Journal Reference: The Lancet. Global health 2023 Apr ; 11(4); . doi: 10.1016/S2214-109X(23)00115-8. Epub 2023 03 16

01.04.2023

Increase in HIV viral suppression in KwaZulu-Natal, South Africa: Community-based cross sectional surveys 2018 and 2013. What remains to be done?

Journal Reference: PloS one 2022 ; 17(3); . doi: 10.1371/journal.pone.0265488. Epub 2022 03 24

01.06.2022

Safety and effectiveness outcomes from a 14-country cohort of patients with multi-drug resistant tuberculosis treated concomitantly with bedaquiline, delamanid and other second-line drugs.

Journal Reference: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2022 Mar 04; . doi: 10.1093/cid/ciac176. Epub 2022 03 04

04.03.2022

Safety of treatment regimens containing bedaquiline and delamanid in the endTB cohort.

Journal Reference: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2022 Jan 13; . doi: 10.1093/cid/ciac019. Epub 2022 01 13

13.01.2022

Higher risk sexual behaviour is associated with unawareness of HIV-positivity and lack of viral suppression - implications for Treatment as Prevention.

Journal Reference: Scientific reports 2017 Nov 23; 7(1); 16117. doi: 10.1038/s41598-017-16382-6. Epub 2017 11 23

23.11.2017

Population-level HIV incidence estimates using a combination of synthetic cohort and recency biomarker approaches in KwaZulu-Natal, South Africa.

Journal Reference: PloS one 2018 ; 13(9); e0203638. doi: 10.1371/journal.pone.0203638. Epub 2018 09 13

01.06.2018

Integrating hepatitis C treatment into multidrug-resistant TB care.

Journal Reference: Public health action 2022 Jun 21; 12(2); . doi: 10.5588/pha.22.0002. Epub 2022 06 23

21.06.2022

Incremental Yield of Including Determine-TB LAM Assay in Diagnostic Algorithms for Hospitalized and Ambulatory HIV-Positive Patients in Kenya.

Journal Reference: PloS one 2017 ; 12(1); e0170976. doi: 10.1371/journal.pone.0170976. Epub 2017 01 26

01.06.2017

The endTB observational study protocol: treatment of MDR-TB with bedaquiline or delamanid containing regimens.

Journal Reference: BMC infectious diseases 2019 Aug 20; 19(1); 733. doi: 10.1186/s12879-019-4378-4. Epub 2019 08 20

20.08.2019

Prevalence of TB and health-seeking behaviour.

Journal Reference: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2022 May 01; 26(5); . doi: 10.5588/ijtld.22.0001. Epub 2022 05 05

01.05.2022

Cost-effectiveness of diagnostic algorithms including lateral-flow urine lipoarabinomannan for HIV-positive patients with symptoms of tuberculosis.

Journal Reference: PloS one 2020 ; 15(1); e0227138. doi: 10.1371/journal.pone.0227138. Epub 2020 01 30

01.06.2020

Progress towards the UNAIDS 90-90-90 goals by age and gender in a rural area of KwaZulu-Natal, South Africa: a household-based community cross-sectional survey.

Journal Reference: BMC public health 2018 03 02; 18(1); 303. doi: 10.1186/s12889-018-5208-0. Epub 2018 03 02

02.03.2018

Urine lipoarabinomannan (LAM) testing for all HIV patients hospitalized in the medical wards identifies a large proportion of patients with tuberculosis at risk of death.

Journal Reference: Open Forum Infectious Diseases; ofaa639; https://doi.org/10.1093/ofid/ofaa639; 23 December 2020

23.12.2020

High prevalence of infection and low incidence of disease in child contacts of patients with drug-resistant tuberculosis: a prospective cohort study.

Journal Reference: Archives of disease in childhood 2018 Dec 06; . doi: 10.1136/archdischild-2018-315411. Epub 2018 12 06

06.12.2018

Feasibility and acceptability of using the novel urine-based FujiLAM test to detect tuberculosis: A multi-country mixed-methods study.

Journal Reference: Journal of clinical tuberculosis and other mycobacterial diseases 2022 May ; 27; . doi: 10.1016/j.jctube.2022.100316. Epub 2022 04 25

01.05.2022

Implementation and Operational Research: Feasibility of Using Tuberculin Skin Test Screening for Initiation of 36-Month Isoniazid Preventive Therapy in HIV-Infected Patients in Resource-Constrained Settings.

Journal Reference: Journal of acquired immune deficiency syndromes (1999) 2016 Apr 01; 71(4); e89-95. doi: 10.1097/QAI.0000000000000895. Epub 2016 07 06

01.04.2016

Mortality in the first six months among HIV-positive and HIV-negative patients empirically treated for tuberculosis.

Journal Reference: BMC infectious diseases 2019 Feb 11; 19(1); 132. doi: 10.1186/s12879-019-3775-z. Epub 2019 02 11

11.02.2019

Systematic, Point-of-Care Urine Lipoarabinomannan (Alere TB-LAM) Assay for Diagnosing Tuberculosis in Severely Immunocompromised HIV-Positive Ambulatory Patients.

Journal Reference: The American journal of tropical medicine and hygiene 2020 Jan 20; . doi: 10.4269/ajtmh.19-0493. Epub 2020 01 20

20.01.2020

A comparison of self-report and antiretroviral detection to inform estimates of antiretroviral therapy coverage, viral load suppression and HIV incidence in Kwazulu-Natal, South Africa.

Journal Reference: BMC infectious diseases 2017 09 29; 17(1); 653. doi: 10.1186/s12879-017-2740-y. Epub 2017 09 29

29.09.2017

Two-fold increase in the HIV viral load suppression rate along with decreased incidence over six years in Ndhiwa sub-county, Kenya.

Journal Reference: Tropical medicine & international health : TM & IH 2021 Oct 12; . doi: 10.1111/tmi.13688. Epub 2021 10 12

12.10.2021

HIV epidemic and cascade of care in 12 east African rural fishing communities: results from a population-based survey in Uganda.

Journal Reference: BMC public health 2020 Jun 19; 20(1); 970. doi: 10.1186/s12889-020-09121-6. Epub 2020 06 19

19.06.2020

Diagnostic value of the urine lipoarabinomannan assay in HIV-positive, ambulatory patients with CD4 below 200 cells/μl in 2 low-resource settings: A prospective observational study.

Journal Reference: PLoS medicine 2019 Apr ; 16(4); e1002792. doi: 10.1371/journal.pmed.1002792. Epub 2019 04 30

01.04.2019

Evaluation of a Lung Ultrasound Score in Hospitalized Adult Patients with COVID-19 in Barcelona, Spain.

Journal Reference: Journal of clinical medicine 2024 Jun 02; 13(11); . doi: 10.3390/jcm13113282. Epub 2024 06 02

02.06.2024

Experiences and perceptions of urine sampling for tuberculosis testing among HIV patients: a multisite qualitative descriptive study.

Journal Reference: BMJ open 2023 Nov 30; 13(11); . doi: 10.1136/bmjopen-2021-058805. Epub 2023 11 30

30.11.2023

Feasibility of using Determine TB-LAM to diagnose tuberculosis in HIV-positive patients in programmatic conditions: a multisite study.

Journal Reference: Global health action 2019 ; 12(1); 1672366. doi: 10.1080/16549716.2019.1672366. Epub 2019 10 15

01.06.2019

Is 6 months of bedaquiline enough? Results from the compassionate use of bedaquiline in Armenia and Georgia.

Journal Reference: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2018 Jul 01; 22(7); 766-772. doi: 10.5588/ijtld.17.0840. Epub 2018 06 19

01.07.2018

Novel FujiLAM assay to detect tuberculosis in HIV-positive ambulatory patients in four African countries: a diagnostic accuracy study.

Journal Reference: The Lancet. Global health 2023 Jan ; 11(1); . doi: 10.1016/S2214-109X(22)00463-6. Epub 2022 12 19

01.01.2023

Outcomes of WHO-conforming, longer, all-oral multidrug-resistant TB regimens and analysis implications.

Journal Reference: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2023 Jun 01; 27(6); . doi: 10.5588/ijtld.22.0613. Epub 2023 05 29

29.05.2023

Performance of the 2007 WHO algorithm to diagnose smear-negative pulmonary tuberculosis in a HIV prevalent setting.

Journal Reference: PloS one 2012 ; 7(12); e51336. doi: 10.1371/journal.pone.0051336. Epub 2012 12 19

01.06.2012

Should Urine-LAM Tests Be Used in TB Symptomatic HIV-Positive Patients When No CD4 Count Is Available? A Prospective Observational Cohort Study From Malawi.

Journal Reference: Journal of acquired immune deficiency syndromes (1999) 2020 01 01; 83(1); 24-30. doi: 10.1097/QAI.0000000000002206. Epub 2020 07 06

01.01.2020

Helena Huerga

Biography

Her publications

COVID-19, tuberculosis, and HIV triad: a prospective observational study in ambulatory patients in Kenya, Uganda, and South Africa.

Adolescents and young adults are the most undiagnosed of HIV and virally unsuppressed in Eastern and Southern Africa: Pooled analyses from five population-based surveys.

Comparative effectiveness of adding delamanid to a multidrug-resistant tuberculosis regimen comprised of three drugs likely to be effective.

Evidence of HIV incidence reduction in young women, but not in adolescent girls, in KwaZulu-Natal, South Africa.

Novel FujiLAM assay to detect tuberculosis in HIV-positive ambulatory patients in four African countries: a diagnostic accuracy study.

Lots of considerations when evaluating the FujiLAM assay - Author's reply.

Increase in HIV viral suppression in KwaZulu-Natal, South Africa: Community-based cross sectional surveys 2018 and 2013. What remains to be done?

Safety and effectiveness outcomes from a 14-country cohort of patients with multi-drug resistant tuberculosis treated concomitantly with bedaquiline, delamanid and other second-line drugs.

Safety of treatment regimens containing bedaquiline and delamanid in the endTB cohort.

Higher risk sexual behaviour is associated with unawareness of HIV-positivity and lack of viral suppression - implications for Treatment as Prevention.

Population-level HIV incidence estimates using a combination of synthetic cohort and recency biomarker approaches in KwaZulu-Natal, South Africa.

Integrating hepatitis C treatment into multidrug-resistant TB care.

Incremental Yield of Including Determine-TB LAM Assay in Diagnostic Algorithms for Hospitalized and Ambulatory HIV-Positive Patients in Kenya.

The endTB observational study protocol: treatment of MDR-TB with bedaquiline or delamanid containing regimens.

Prevalence of TB and health-seeking behaviour.

Cost-effectiveness of diagnostic algorithms including lateral-flow urine lipoarabinomannan for HIV-positive patients with symptoms of tuberculosis.

Progress towards the UNAIDS 90-90-90 goals by age and gender in a rural area of KwaZulu-Natal, South Africa: a household-based community cross-sectional survey.

Urine lipoarabinomannan (LAM) testing for all HIV patients hospitalized in the medical wards identifies a large proportion of patients with tuberculosis at risk of death.

High prevalence of infection and low incidence of disease in child contacts of patients with drug-resistant tuberculosis: a prospective cohort study.

Feasibility and acceptability of using the novel urine-based FujiLAM test to detect tuberculosis: A multi-country mixed-methods study.

Implementation and Operational Research: Feasibility of Using Tuberculin Skin Test Screening for Initiation of 36-Month Isoniazid Preventive Therapy in HIV-Infected Patients in Resource-Constrained Settings.

Mortality in the first six months among HIV-positive and HIV-negative patients empirically treated for tuberculosis.

Systematic, Point-of-Care Urine Lipoarabinomannan (Alere TB-LAM) Assay for Diagnosing Tuberculosis in Severely Immunocompromised HIV-Positive Ambulatory Patients.

A comparison of self-report and antiretroviral detection to inform estimates of antiretroviral therapy coverage, viral load suppression and HIV incidence in Kwazulu-Natal, South Africa.

Two-fold increase in the HIV viral load suppression rate along with decreased incidence over six years in Ndhiwa sub-county, Kenya.

HIV epidemic and cascade of care in 12 east African rural fishing communities: results from a population-based survey in Uganda.

Diagnostic value of the urine lipoarabinomannan assay in HIV-positive, ambulatory patients with CD4 below 200 cells/μl in 2 low-resource settings: A prospective observational study.

Evaluation of a Lung Ultrasound Score in Hospitalized Adult Patients with COVID-19 in Barcelona, Spain.

Experiences and perceptions of urine sampling for tuberculosis testing among HIV patients: a multisite qualitative descriptive study.

Feasibility of using Determine TB-LAM to diagnose tuberculosis in HIV-positive patients in programmatic conditions: a multisite study.

Is 6 months of bedaquiline enough? Results from the compassionate use of bedaquiline in Armenia and Georgia.

Novel FujiLAM assay to detect tuberculosis in HIV-positive ambulatory patients in four African countries: a diagnostic accuracy study.

Outcomes of WHO-conforming, longer, all-oral multidrug-resistant TB regimens and analysis implications.

Performance of the 2007 WHO algorithm to diagnose smear-negative pulmonary tuberculosis in a HIV prevalent setting.

Should Urine-LAM Tests Be Used in TB Symptomatic HIV-Positive Patients When No CD4 Count Is Available? A Prospective Observational Cohort Study From Malawi.