Publications

ENG

Culture conversion at six months in patients receiving delamanid-containing regimens for the treatment of multidrug-resistant tuberculosis.

Abstract

Delamanid should be effective against highly resistant strains of M. tuberculosis, but uptake has been slow globally.

Authors: Seung KJ Khan P Franke MF Ahmed S Aiylchiev S Alam M Putri FA Bastard M Docteur W Gottlieb G Hewison C Islam S Khachatryan N Kotrikadze T Khan U Kumsa A Lecca L Tassew YM Melikyan N Naing YY Oyewusi L Rich M Wanjala S Yedilbayev A Huerga H Mitnick CD
Journal Reference: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2019 Nov 02; (); Array. doi: 10.1093/cid/ciz1084. Epub 2019 11 02
antitubercular agents delamanid extensively drug-resistant tuberculosis multidrug-resistant tuberculosis
ENG

Distribution of advanced HIV disease from three high HIV prevalence settings in Sub-Saharan Africa: a secondary analysis data from three population-based cross-sectional surveys in Eshowe (South Africa), Ndhiwa (Kenya) and Chiradzulu (Malawi).

Abstract

: Despite substantial progress in antiretroviral therapy (ART) scale up, some people living with HIV (PLHIV) continue to present with advanced HIV disease, contributing to ongoing HIV-related morbidity and mortality.: We aimed to quantify population-le

Authors: Chihana ML Huerga H Van Cutsem G Ellman T Goemaere E Wanjala S Masiku C Szumilin E Etard JF Maman D Davies MA
Journal Reference: Global health action 2019 ; 12(1); 1679472. doi: 10.1080/16549716.2019.1679472. Epub 2019 11 04
ART Africa CD4 HIV population-level
ENG

Adherence and population pharmacokinetic properties of amodiaquine when used for seasonal malaria chemoprevention in African children.

Abstract

Poor adherence to seasonal malaria chemoprevention (SMC) might affect the protective effectiveness of SMC.

Authors: Ding J Coldiron ME Assao B Guindo O Blessborn D Winterberg M Grais RF Koscalova A Langendorf C Tarning J
Journal Reference: Clinical pharmacology and therapeutics 2019 Oct 25; (); Array. doi: 10.1002/cpt.1707. Epub 2019 10 25
ENG

Should urine-LAM tests be used in TB symptomatic HIV-positive patients when no CD4 count is available? A prospective observational cohort study from Malawi.

Abstract

BACKGROUND: Current eligibility criteria for urine lateral-flow-lipoarabinomannan assay (LF-LAM) in ambulatory, HIV-positive patients rely on the CD4 count.

Authors: Huerga H Mathabire Rucker SC Bastard M Dimba A Kamba C Amoros I Szumilin E
Journal Reference: Journal of acquired immune deficiency syndromes (1999) 2019 Oct 16; (); Array. doi: 10.1097/QAI.0000000000002206. Epub 2019 10 16
ENG

Evaluation of OMNIgene® SPUTUM and ethanol reagent for preservation of sputum prior to Xpert and culture testing in Uganda.

Abstract

Xpert MTB/RIF (Xpert) and culture are the most reliable methods for tuberculosis diagnosis but are still poorly accessible in many low resource countries.

Authors: Ardizzoni E Orikiriza P Ssuuna C Nyehangane D Gumsboga M Taremwa IM Turyashemererwa E Mwanga-Amumpaire J Langendorf C Bonnet M
Journal Reference: Journal of clinical microbiology 2019 Oct 16; (); Array. doi: 10.1128/JCM.00810-19. Epub 2019 10 16
ENG

Factors influencing participation in an Ebola vaccine trial among front-line workers in Guinea.

Abstract

BACKGROUND: Alongside the clinical aspects of the immunogenicity and safety trial of an Ebola vaccine deployed among front-line workers, a qualitative study was conducted to describe motivations behind individuals' decisions to partici

Authors: Grantz KH Claudot P Kambala M Kouyaté M Soumah A Boum Y Juan-Giner A Jemmy JP Cummings DAT Grais RF
Journal Reference: Vaccine 2019 Oct 14; (); Array. doi: 10.1016/j.vaccine.2019.09.094. Epub 2019 10 14
Ebola virus disease Guinea Healthcare workers Qualitative Research design rVSV vaccine
ENG

Hand hygiene compliance and environmental contamination with gram-negative bacilli in a rural hospital in Madarounfa, Niger.

Abstract

BACKGROUND: Healthcare-associated infections pose a major, yet often preventable risk to patient safety.

Authors: Tang K Berthé F Nackers F Hanson K Mambula C Langendorf C Marquer C Isanaka S
Journal Reference: Transactions of the Royal Society of Tropical Medicine and Hygiene 2019 Oct 14; (); Array. doi: 10.1093/trstmh/trz070. Epub 2019 10 14
Niger gram-negative bacilli hand hygiene healthcare personnel healthcare-associated infections
ENG

What is the best culture conversion prognostic marker for patients treated for multidrug-resistant tuberculosis?

Abstract

Identification of good prognostic marker for tuberculosis (TB) treatment response is a necessary step on the path towards a surrogate marker to reduce TB trial duration.

Authors: Bastard M Sanchez-Padilla E Hayrapetyan A Kimenye K Khurkhumal S Dlamini T Fadul Perez S Telnov A Hewison C Varaine F Bonnet M
Journal Reference: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2019 Oct 01; 23(10); 1060-1067. doi: 10.5588/ijtld.18.0649. Epub 2019 10 19
ENG

Mobile community-based active case-finding for tuberculosis among older populations in rural Cambodia.

Abstract

To systematically screen older rural populations in Cambodia for tuberculosis (TB) and develop an effective active case-finding (ACF) model for this TB high-risk group.

Authors: Camelique O Scholtissen S Dousset JP Bonnet M Bastard M Hewison C
Journal Reference: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2019 Oct 01; 23(10); 1107-1114. doi: 10.5588/ijtld.18.0611. Epub 2019 10 19
ENG

Beyond wasted and stunted-a major shift to fight child undernutrition.

Abstract

Child undernutrition refers broadly to the condition in which food intake is inadequate to meet a child's needs for physiological function, growth, and the capacity to respond to illness.

Authors: Wells JCK Briend A Boyd EM Berkely JA Hall A Isanaka S Webb P Khara T Dolan C
Journal Reference: The Lancet. Child & adolescent health 2019 Sep 11; (); Array. doi: 10.1016/S2352-4642(19)30244-5. Epub 2019 09 11