Publications

BACKGROUND: Meningococcal meningitis remains a major public health challenge in Africa's meningitis belt despite the successful elimination of serogroup A epidemics following MenAfriVac introduction.

BACKGROUND: HIV remains a major public health challenge globally, including in the Central African Republic (CAR).

Children with severe acute malnutrition (SAM) are at high risk of invasive infection. In sub-Saharan Africa, invasive non-typhoidal (iNTS) serovars are a leading cause of paediatric bloodstream infection.

OBJECTIVES: To estimate the carbon footprint of a vaccine trial conducted in Uganda and to identify opportunities to reduce greenhouse gas emissions in future trials.

BACKGROUND: Lassa fever vaccine trials are hampered by knowledge gaps on disease incidence, at-risk populations, sequelae, and transmission risks.

BACKGROUND: A large measles outbreak occurred in Yakusu Health Zone, Democratic Republic of the Congo, between January 2018 and June 2019.

BACKGROUND: The expanding volume and increasing complexity of clinical research in East Africa, driven by emerging and re-emerging infectious diseases, has increased the need for strong regulatory monitoring systems.

OBJECTIVES: Pediatric Early Warning Systems (PEWSs) have been used to predict adverse outcomes among hospitalized patients, though evidence is limited in resource-limited settings.