Publications

Low-Dose Yellow Fever Vaccine in Adults in Africa.

Abstract

BACKGROUND: Yellow fever vaccine is highly effective with a single dose, but vaccine supply is limited. The minimum dose requirements for seroconversion remain unknown.

Kimathi D Juan-Giner A Bob NS Orindi B Namulwana ML Diatta A Cheruiyot S Fall G Dia M Hamaluba MM Nyehangane D Karanja HK Gitonga JN Mugo D Omuoyo DO Hussein M Oloo E Kamau N Wafula J Bendera J Silvester N Mwavita J Joshua M Mwendwa J Agababyona C Ngetsa C Aisha N Moki F Buluku T Munene M Mwanga-Amumpaire J Lutwama J Kayiwa J Kamaara E Barrett AD Kaleebu P Bejon P Sall AA Grais RF Warimwe GM
The New England journal of medicine 2025 Feb 20; 392(8); . doi: 10.1056/NEJMoa2407293. Epub 2025 02 19

Impact of a multi-pronged cholera intervention in an endemic setting.

Abstract

Cholera is a bacterial water-borne diarrheal disease transmitted via the fecal-oral route that causes high morbidity in sub-Saharan Africa and Asia. It is preventable with vaccination, and Water, Sanitation, and Hygiene (WASH) improvements.

Blake A Walder A Hanks EM Welo PO Luquero F Bompangue D Bharti N
PLoS neglected tropical diseases 2025 Feb ; 19(2); . doi: 10.1371/journal.pntd.0012867. Epub 2025 02 19

Antibiotic resistance in the Middle East and Southern Asia: a systematic review and meta-analysis.

Abstract

INTRODUCTION: Despite global surveillance efforts, antibiotic resistance (ABR) is difficult to address in low- and middle-income countries (LMICs).

Rachel Mathu Elizabeth Diago-Navarro Emily Lynch Marie-Amélie Degail Janet Ousley Rupa Kanapathipillai et al.
JAC-Antimicrobial Resistance, Volume 7, Issue 1, February 2025. doi:10.1093/jacamr/dlaf010 Epub 2025 02 19
ABR Systematic Review Meta-analysis

Safety of 3-month rifampicin-isoniazid TPT in child household contacts in a community-based intervention.

Abstract

BACKGROUNDThe WHO recommends shorter TB preventive treatment (TPT) regimens and decentralised delivery models to improve effectiveness.

Tchakounte Youngui B Tchounga BK Atwine D Vasiliu A Cuer B Simo L Okello R Tchendjou P Kuate Kuate A Turyahabwe S Cohn J Graham SM Casenghi M Bonnet M
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2025 Feb 01; 29(2); . doi: 10.5588/ijtld.24.0311. Epub 2025 02 01

Characteristics of children and adolescents with multidrug-resistant and rifampicin-resistant tuberculosis and their association with treatment outcomes: a systematic review and individual participant data meta-analysis.

Abstract

BACKGROUND: There are few data on the treatment of children and adolescents with multidrug-resistant (MDR) or rifampicin-resistant (RR) tuberculosis, especially with more recently available drugs and regimens.

Garcia-Prats AJ Garcia-Cremades M Cox V Kredo T Dunbar R Schaaf HS Seddon JA Furin J Achar J Radke K Sachs T Abubakirov A Ahmed S Akkerman OW Al Ani NA Amanullah F Ahmad N Anderson LF Asfaw M Bango F Bauer T Becerra M Boeree M Brinkmann F Brown R Brust J Campbell JR Carvalho AC Carvalho I Cegielski JP Centis R Chan ED Chauhan S Chiang SS Chan PC D'Ambrosio L Dalcolmo M Daneilyan N de Vries G Draper HR Fairlie L Francis JR Franke M Gegia M Restrepo CG Guenther A Gureva T Haecker B Harausz E Hewison C Hicks RM Huerga H Hughes J Isaakidis P Kadri SM Khan MA Kotrikadze T Kuksa L Lachenal N Lange C Lecca L Lopez-Varela E Lucena S Mariandyshev A Mattoo S Mendez-Echevarria A Migliori GB Mitnick C Mohr-Holland E Mulanda W Murzabakova T Myrzalieve B Ndjeka N Niemann S Ozere I Padayatchi N Parmar M Parpieva N Manzur-Ul-Alam M Rybak N Sachdeva KS Salmon K Santiago-Garcia B Schaub D Shah I Shah S Shah V Sharma S Shim TS Shin S Sinha A Skrahina A Solanki H Solans BP Soriano-Arandes A Toktogonova A van der Werf T Velásquez GE Williams B Yim JJ Savic R Hesseling A
The Lancet. Child & adolescent health 2025 Feb ; 9(2); . doi: 10.1016/S2352-4642(24)00330-4. Epub 2025 01 24

Oral Regimens for Rifampin-Resistant, Fluoroquinolone-Susceptible Tuberculosis.

Abstract

BACKGROUND: For decades, poor treatment options and low-quality evidence plagued care for patients with rifampin-resistant tuberculosis.

Guglielmetti L Khan U Velásquez GE Gouillou M Abubakirov A Baudin E Berikova E Berry C Bonnet M Cellamare M Chavan V Cox V Dakenova Z de Jong BC Ferlazzo G Karabayev A Kirakosyan O Kiria N Kunda M Lachenal N Lecca L McIlleron H Motta I Toscano SM Mushtaque H Nahid P Oyewusi L Panda S Patil S Phillips PPJ Ruiz J Salahuddin N Garavito ES Seung KJ Ticona E Trippa L Vasquez DEV Wasserman S Rich ML Varaine F Mitnick CD
The New England journal of medicine 2025 Jan 30; 392(5); . doi: 10.1056/NEJMoa2400327. Epub 2025 01 29

Beyond COVID-19, the case for collecting, analysing and using sex-disaggregated data and gendered data to inform outbreak response: a scoping review.

Abstract

INTRODUCTION: Understanding sex and gender differences during outbreaks is critical to delivering an effective response.

Gales M Yonally Phillips EL Zilversmit Pao L Dubray C Rodriguez Ribas Elizalde C Heidari S Degail MA Meudec M Siddiqui MR Carter SE
BMJ global health 2025 Jan 19; 10(1); . doi: 10.1136/bmjgh-2024-015900. Epub 2025 01 19
Global Health Infections, diseases, disorders, injuries Maternal health Public Health Systematic review

Effect of mass campaigns with full and fractional doses of pneumococcal conjugate vaccine (Pneumosil) on the reduction of nasopharyngeal pneumococcal carriage in Niger: a three-arm, open-label, cluster-randomised trial.

Abstract

BACKGROUND: In settings with low pneumococcal conjugate vaccine (PCV) coverage, multi-age cohort mass campaigns could increase population immunity, and fractional dosing could increase affordability.

Coldiron ME Soumana I Baudin E Langendorf C Mamiafo Tchoula C Brah S Karani A Gallagher KE Kagucia EW Scott JAG Grais RF
The Lancet. Infectious diseases 2025 Jan 08; . doi: 10.1016/S1473-3099(24)00719-9. Epub 2025 01 08

The effectiveness of two doses of recombinant hepatitis E vaccine in response to an outbreak in Bentiu, South Sudan: a case-control and bias indicator study.

Abstract

BACKGROUND: Hepatitis E virus (HEV) is a leading cause of acute viral hepatitis, particularly in Asia and Africa, where HEV genotypes 1 and 2 are prevalent.

Nesbitt RC Kinya Asilaza V Alvarez C Gitahi P Nkemenang P Duncker J Haile M Gakima P Wamala JF Loro FB Koyuncu A Biem D Albela M Rull M Gignoux E Rumunu J Eckerle I Ciglenecki I Azman AS
The Lancet. Infectious diseases 2025 Jan 08; . doi: 10.1016/S1473-3099(24)00657-1. Epub 2025 01 08

Exposure to COVID-19 Pandemic-Related Stressors and Their Association With Distress, Psychological Growth and Drug Use in People With HIV in Nouvelle Aquitaine, France (ANRS CO3 AQUIVIH-NA Cohort-QuAliV-QuAliCOV Study).

Abstract

We investigated people living with HIV (PLWH)'s exposure to COVID-19 pandemic stressors and their association with distress, psychological growth, and substance use.

Ben Farhat J Hessamfar M Neau D Farbos S Lazaro E Duffau P Rouanes N Cazanave C Pistone T Rispal P Vandenhende MA Krzyzanowsky C Leleux O Wittkop L Bonnet F Barger D
AIDS and behavior 2025 Jan 06; . doi: 10.1007/s10461-024-04588-5. Epub 2025 01 06
COVID-19 Cannabis Distress Drugs HIV Psychological growth