BACKGROUND: Millions of individuals at risk of tuberculosis are given tuberculosis preventive treatment (TPT) annually.
BACKGROUND: Tuberculosis is the leading cause of death in children living with HIV, and is challenging to diagnose owing to the limitations of microbiological approaches.
INTRODUCTION: Task-shifting tuberculosis (TB) rapid molecular testing from laboratory technicians to nurses could help decentralise TB diagnosis at primary health centres (PHCs) and allow in-ward testing to shorten treatment decision f
Accurate and accessible diagnostics for hepatitis E virus (HEV) are essential for outbreak preparedness and surveillance, particularly in low-resource settings.
INTRODUCTION: Children discharged after in-hospital treatment for severe anaemia or severe malaria in sub-Saharan Africa remain at high risk of readmission and death, particularly in malaria-endemic settings where recurrent infections
BACKGROUND: Despite wide-scale implementation of malaria prevention strategies, including seasonal malaria chemoprevention (SMC), a substantial disease burden persists.
INTRODUCTION: Control of tuberculosis (TB) in children remains a major challenge globally.
BACKGROUND: Meningococcal meningitis remains a major public health challenge in Africa's meningitis belt despite the successful elimination of serogroup A epidemics following MenAfriVac introduction.
BACKGROUND: Observational studies investigating causal (aetiological) questions often address confounding bias using data-driven predictive models where variables are selected regardless of their causal role, challenging interpretation
We developed a pragmatic approach to calibrating computer-aided detection (CAD) thresholds in a tuberculosis (TB) active case finding (ACF) project in the Philippines, assessing its feasibility and acceptability in a high-burden urban setting.
