Publications

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The Frequency and Incidence of QT Prolongation with Extended Use of Bedaquiline or Delamanid in a Large, Multi-Country MDR/RR-TB Cohort.

Abstract

BACKGROUND: The 2022 WHO guidelines on multi-drug/rifampicin resistant tuberculosis (MDR/RR-TB) recommend six months of bedaquiline (Bdq) in the all-oral 9-month shorter regimen and six months or longer for Bdq and delamanid (Dlm) in t

Khan U Rich M Franke M Lachenal N Ahmed S Bekele A Isani AK Hewison C Sari CYI Tan CL Varaine F Flores EH Putri FA Faqirzai J Beauchamp J Vo LNQ Siddiqui MR Seung K Bastard M Nkunkanyirazo P Kiria N Khan M Algozhin Y Melikyan N Saki NA Vilbrun SC Fatima R Naing YY Islam S Mamsa S Mitnick C Huerga H Khan PY
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2024 Dec 10; . doi: 10.1093/cid/ciae601. Epub 2024 12 10
Bedaquiline Delamanid Extended use QT prolongation adverse events

Pregnancy and neonatal outcomes in Eastern Democratic Republic of the Congo: a systematic review.

Abstract

BACKGROUND: Conflict is known to impact maternal and neonatal health in Eastern Democratic Republic of the Congo (DRC), an area of longstanding insecurity.

Kambale Kasonia Hannah Brindle Daniela Manno Tansy Edwards Soazic Gardais Grace Mambula et al.
Front. Glob. Womens Health, 05 December 2024; Volume 5; doi:10.3389/fgwh.2024.1412403. Epub 2024 12 05
pregnancy neonatal outcomes eastern DRC conflict

Inferring the proportion of undetected cholera infections from serological and clinical surveillance in an immunologically naive population.

Abstract

Most infections with pandemic are thought to result in subclinical disease and are not captured by surveillance. Previous estimates of the ratio of infections to clinical cases have varied widely (2 to 100 infections per case).

Finger F Lemaitre J Juin S Jackson B Funk S Lessler J Mintz E Dely P Boncy J Azman AS
Epidemiology and infection 2024 Dec 02; 152; . doi: 10.1017/S0950268824000888. Epub 2024 12 02

High immunity and low mortality after Omicron and mass event in Cameroon despite low vaccination.

Abstract

BACKGROUND: Little is known about the evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) immunity in African communities.

Boum Y Matchim L Guimsop DK Buri BD Bebell LM Jaudel YSF Njuwa FKG Danirla DB Youm E Ntone R Tchame CR Tchiasso D Essaka R Eyong JB Ngosso A Nanda H Fondze NR Ndifon MN Eteki L Ghislain YFC Messi BYE Moustapha H Hamdja M Essomba RG Mandeng N Modeste TAK Bisseck AZ Eyangoh SI Njouom R Okomo MC Esso L Emilienne E Mballa GE
Journal of public health in Africa 2024 ; 15(1); . doi: 10.4102/jphia.v15i1.649. Epub 2024 11 07
Africa SARS-CoV-2 immunity mortality seroprevalence

rVSV-ZEBOV vaccination in people with pre-existing immunity to Ebolavirus: an open-label safety and immunogenicity study in Guinean communities affected by Ebola virus disease (l'essai proches).

Abstract

BACKGROUND: Zaire Ebolavirus disease (EVD) outbreaks can be controlled using rVSV-ZEBOV vaccination and other public health measures.

Watson CH Gsell PS Hall Y Camacho A Riveros X Enwere G Vicari A Nadlaou SD Toure A Sani IM Diallo A Kolie C Duraffour S Ifono K Maomou A Dore K Djidonou HA Bagayoko A Damey PP Camara MN Diallo FB Oumar FT Toure K Diaby ML Sylla L Conde D Kaba IL Tipton T Eggo RM Marks M Roberts CH Strecker T Günther S Keita S Edmunds WJ Carroll MW Henao-Restrepo AM
BMC medicine 2024 Nov 07; 22(1); . doi: 10.1186/s12916-024-03726-z. Epub 2024 11 07
Cohort study Ebola Ebola virus disease Immunogenicity RVSV-ZEBOV Safety Vaccine

Implementation of digital chest radiography for childhood tuberculosis diagnosis at district hospital level in six high tuberculosis burden and resources limited countries.

Abstract

OBJECTIVES: Chest x-ray (CXR) plays an important role in childhood tuberculosis (TB) diagnosis, but access to quality CXR remains a major challenge in resource-limited settings.

Melingui BF Basant J Taguebue JV Massom DM Leroy Terquem E Norval PY Salomao A Dim B Tek CE Borand L Khosa C Moh R Mwanga-Amumpere J Eang MT Manhiça I Mustapha A Balestre E Beneteau S Wobudeya E Marcy O Orne-Gliemann J Bonnet M
Tropical medicine & international health : TM & IH 2024 Nov 03; . doi: 10.1111/tmi.14053. Epub 2024 11 03
children digital chest x‐ray implementation resources limited countries tuberculosis

Rapid Decision Algorithm for Patient Triage during Ebola Outbreaks.

Abstract

The low specificity of Ebola virus disease clinical signs increases the risk for nosocomial transmission to patients and healthcare workers during outbreaks.

Ardiet DL Nsio J Komanda G Coulborn RM Grellety E Grandesso F Kitenge R Ngwanga DL Matady B Manangama G Mossoko M Ngwama JK Mbala P Luquero F Porten K Ahuka-Mundeke S
Emerging infectious diseases 2024 Nov ; 30(11); . doi: 10.3201/eid3011.231650. Epub 2024 10 24
Algorithm Democratic Republic of the Congo Ebola clinical signs contact epidemics exposure outbreaks predictors symptomatology symptoms triage

Safety of hepatitis E vaccine in pregnancy: an emulated target trial following a mass reactive vaccination campaign in Bentiu internally displaced persons camp, South Sudan.

Abstract

BACKGROUND: Epidemic forms of hepatitis E cause high mortality among pregnant people, with case fatality risks over 30% and adverse fetal outcomes.

Nesbitt RC Azman AS Asilaza VK Edwards JK Gitahi P Nkemenang P Duncker J Haile M Gakima P Wamala JF Loro FB Biem D Staderini N Albela M Rull M Rumunu J Ciglenecki I Gignoux E
The Lancet. Global health 2024 Nov ; 12(11); . doi: 10.1016/S2214-109X(24)00321-8. Epub 2024 10 18

Dynamic factors associated with COVID-19 vaccine uptake in Cameroon between 2021 and 2022.

Abstract

BACKGROUND: Little is known about attitudes towards COVID-19 vaccination in sub-Saharan Africa, where immunisation coverage is the lowest in the world.

Tchiasso D Mendjime P Fai KN Wandji BSN Yuya F Youm É Stanton AM Karimu I Bebell LM Matchim L Buri BD Ntone R Yonta C Tchame CR Essaka R Eyong JB Ngosso A Nanda H Nsaibirni R Ndifon M Eteki L Mandeng N Bisseck AZ Koku MT Epée E Mballa GE Ndoula ST Esso L Boum Y
Journal of public health in Africa 2024 ; 15(1); . doi: 10.4102/jphia.v15i1.578. Epub 2024 10 24
COVID-19 Cameroon hesitancy heterogeneity vaccine

External quality assurance of chest X-ray interpretation to strengthen diagnosis of childhood TB.

Abstract

BACKGROUND: Chest X-ray (CXR) misinterpretation negatively affects the accuracy of childhood TB diagnosis. External quality assurance (EQA) could strengthen CXR reading skills.

Melingui BF Leroy-Terquem E Taguebue JV Eap TC Borand L Khosa C Moh R Mwanga-Amumpaire J Beneteau S Eang MT Manhiça I Mustapha A Marcy O Wobudeya E Norval PY Bonnet M
IJTLD open 2024 Oct ; 1(10); . doi: 10.5588/ijtldopen.24.0328. Epub 2024 10 01
chest X-ray children diagnosis external quality assurance limited-resources countries tuberculosis