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Dengue in Western Uganda: a prospective cohort of children presenting with undifferentiated febrile illness.


BACKGROUND: The spatial distribution and burden of dengue in sub-Saharan Africa remains highly uncertain, despite high levels of ecological suitability.

Auteurs: Boyce RM Collins M Muhindo R Nakakande R Ciccone EJ Grounds S Espinoza D Zhu Y Matte M Ntaro M Nyehangane D Juliano JJ Mulogo EM
Référence de l'article: BMC infectious diseases 2020 Nov 11; 20(1); 835. doi: 10.1186/s12879-020-05568-5. Epub 2020 11 11
Arbovirus Dengue Epidemiology Fever Uganda

Implementation and operational feasibility of SAMBA I HIV-1 semi-quantitative viral load testing at the point of care in rural settings in Malawi and Uganda.


OBJECTIVE: We monitored a large-scale implementation of the Simple Amplification-Based Assay semi-quantitative viral load test for HIV-1 version I (SAMBA I Viral Load = SAMBA I VL) within Médecins Sans Frontières' HIV programmes in Mal

Auteurs: Gueguen M Nicholas S Poulet E Schramm B Szumilin E Wolters L Wapling J Ajule E Rakesh A Mwenda R Kiyaga C Balkan S
Référence de l'article: Tropical medicine & international health : TM & IH 2020 Nov 07; (); Array. doi: 10.1111/tmi.13519. Epub 2020 11 07
Malawi POC testing SAMBA I Uganda descriptive analysis

Household air pollution and under-five mortality in sub-Saharan Africa: an analysis of 14 demographic and health surveys.


BACKGROUND: Globally, over four million deaths are attributed to exposure to household air pollution (HAP) annually.

Auteurs: Bickton FM Ndeketa L Sibande GT Nkeramahame J Payesa C Milanzi EB
Référence de l'article: Environmental health and preventive medicine 2020 Nov 04; 25(1); 67. doi: 10.1186/s12199-020-00902-4. Epub 2020 11 04
Demographic Health Survey Household air pollution Sub-Saharan Africa Under-five mortality

Point-of-Care Approaches for Meningitis Diagnosis in a Low-Resource Setting (Southwestern Uganda): Observational Cohort Study Protocol of the "PI-POC" Trial.


BACKGROUND: A timely differential diagnostic is essential to identify the etiology of central nervous system (CNS) infections in children, in order to facilitate targeted treatment, manage patients, and improve clinical outcome.

Auteurs: Gaudenzi G Kumbakumba E Rasti R Nanjebe D Réu P Nyehangane D Mårtensson A Nassejje M Karlsson J Mzee J Nilsson P Businge S Loh E Boum Ii Y Andersson-Svahn H Gantelius J Mwanga-Amumpaire J Alfvén T
Référence de l'article: JMIR research protocols 2020 Nov 04; 9(11); e21430. doi: 10.2196/21430. Epub 2020 11 04
Uganda central nervous system infections children diagnostics global health low-resource settings meningitis pediatrics

Cost-effectiveness of screening and treatment using direct-acting antivirals for chronic Hepatitis C virus in a primary care setting in Karachi, Pakistan.


Despite the availability of effective direct-acting antiviral (DAA) treatments for Hepatitis C virus (HCV) infection, many people remain undiagnosed and untreated.

Auteurs: Mafirakureva N Lim AG Khalid GG Aslam K Campbell L Zahid H Van den Bergh R Falq G Fortas C Wailly Y Auat R Donchuk D Loarec A Coast J Vickerman P Walker JG
Référence de l'article: Journal of viral hepatitis 2020 Oct 14; (); Array. doi: 10.1111/jvh.13422. Epub 2020 10 14
Pakistan chronic hepatitis C cost effectiveness low income population treatment costs

Estimation of Rift Valley fever virus spillover to humans during the Mayotte 2018-2019 epidemic.


Rift Valley fever (RVF) is an emerging, zoonotic, arboviral hemorrhagic fever threatening livestock and humans mainly in Africa. RVF is of global concern, having expanded its geographical range over the last decades.

Auteurs: Métras R Edmunds WJ Youssouffi C Dommergues L Fournié G Camacho A Funk S Cardinale E Le Godais G Combo S Filleul L Youssouf H Subiros M
Référence de l'article: Proceedings of the National Academy of Sciences of the United States of America 2020 Sep 29; 117(39); 24567-24574. doi: 10.1073/pnas.2004468117. Epub 2020 09 14
One Health Rift Valley fever epidemics modeling spillover

Development of a patient rated scale for mental health global state for use during humanitarian interventions.


OBJECTIVE: We present the results of a cross-cultural validation of the Mental Health Global State (MHGS) scale for adults and adolescents (<14 years old).

Auteurs: Llosa AE Martínez-Viciana C Carreño C Evangelidou S Casas G Marquer C Moro MR Falissard B Grais RF
Référence de l'article: International journal of methods in psychiatric research 2020 Sep 18; (); e1850. doi: 10.1002/mpr.1850. Epub 2020 09 18
conflict global scale humanitarian intervention mental health psychology