BACKGROUND: Lassa fever vaccine trials are hampered by knowledge gaps on disease incidence, at-risk populations, sequelae, and transmission risks.
BACKGROUND: A large measles outbreak occurred in Yakusu Health Zone, Democratic Republic of the Congo, between January 2018 and June 2019.
BACKGROUND: The expanding volume and increasing complexity of clinical research in East Africa, driven by emerging and re-emerging infectious diseases, has increased the need for strong regulatory monitoring systems.
OBJECTIVES: Pediatric Early Warning Systems (PEWSs) have been used to predict adverse outcomes among hospitalized patients, though evidence is limited in resource-limited settings.
BACKGROUND: Peripheral neuropathy frequently leads to linezolid dose reductions or interruptions during multidrug- or rifampicin-resistant tuberculosis (MDR/RR-TB) treatment.
Cholera has re-emerged as a major global public health emergency, with reported cases and deaths tripling between 2022 and 2025 especially in Africa, due to climate shocks, population displacement, fragile water and sanitation systems, and delays in la
BACKGROUND: Globally, about 2.3 million neonates die annually, most of them in low-resource and conflict-affected countries.
Burn injuries represent a challenge in the Gaza Strip, where access to rehabilitation services is constrained by ongoing conflict and limited healthcare resources.
CONTEXT: Seasonal Malaria Chemoprevention (SMC) based on sulfadoxine-pyrimethamine (SP) and Amodiaquine (AQ) has been recommended by the WHO since 2012 for areas where malaria is endemic but seasonal.
OBJECTIVES: To compare the efficacy and safety of intravenous rehydration (IVR) versus oral rehydration (OR) strategies in children with severe acute malnutrition (SAM) and severe dehydration.
