Scientific Day 2018

Corps éditorial

Introduction

The greatest asset of the Epicentre research group is its organic relationship with MSF. Behind the scenes, our shared story is written, the story of committed individuals, projects, experiences, risks taken and results shared. This is the story that our scientific day tells each year.

For several years, MSF has been involved in developing pediatric interventions. Many children first visit the doctor or are hospitalized with an infectious disease, often accompanied by malnutrition. The healthcare teams must, therefore, consider the usefulness of systematic antibiotic treatment, the risk of acquiring a nosocomial infection, possibly with a resistant pathogen, and the effect that supplemental nutrition for mothers during pregnancy can have on the immunological response to oral vaccines.

Etiological diagnosis and treatment of severe infections remain difficult questions as well. Thus, MSF and Epicentre, along with the Institut Pasteur, have begun developing a new rapid diagnostic test that is suitable for use in the areas where we work. Although this project did not reach its objectives, lessons learned will be described. Another approach will be presented with regards to pediatric tuberculosis, for which the objective is to determine how to best use existing methods.

The improvement of healthcare practices remains an important direction for our work. The third session will illustrate this point through several evaluations: the efficacy of systematic administration of antituberculosis treatment to patients infected with HIV, the place that recently developed medications for hepatitis C have in MSF programs, for the treatment of resistant tuberculosis, and finally the impact of ciprofloxacin in the response to meningitis epidemics in Niger.

After the poster session, we will return to the emergency situations in which Epicentre has supported MSF. This year, for example, this ambition has been realized in Bangladesh, northern Cameroon, Iraq, and Yemen. We will see how our work has helped clarify operational decisions and support MSF’s public statements.

The program below is a testament to our intention of placing research at the heart of healthcare programs and thereby impacting national policies. But this is not the only aspect of what is, in reality, a multidisciplinary approach.We have assembled a group of colleagues who will discuss their personal experiences regarding the question: “What can research change?”

Programme

8.45 – Welcome and coffee

9.30 – Introductory remarks – Emmanuel Baron

9.45 – Session 1: Pediatrics

Moderator: James Berkley, Kenya Medical Research Institute

  • Bacterial bloodstsream infections in a pediatric hospital in Niger. Céline Langendorf
  • Routine antibiotics in the treatment of uncomplicated severe acute malnutrition in Niger. Brigitte Chokote
  • Nutritional support to pregnant women in Niger. Sheila Isanaka
     

10.30 – Session 2: Diagnostic
Moderator: Amadou Sall, Institut Pasteur Dakar

  • Diagnostic of tuberculosis in children. Maryline Bonnet
  • Development of diagnostics for pediatric infections. Anne-Laure Page
     

11.20 – Coffee break

11.40 – Session 3: Delivering care

Moderator: Els Torreele, Campaign for Access to Essential Medicines

  • Treating Hepatitis C in MSF programs. Anne Loarec
  • Introducing two new drugs for resistant tuberculosis. Helena Huerga
  • Antibiotic prophylaxis as a response to a meningococcal meningitis outbreak. Matthew Coldiron
  • Systematic and empirical treatment of tuberculosis in HIV advanced infected patients. Conrad Muzoora
     

13.00 – Lunch on site

14.00 – Poster session

15h00 – Session 4: Emergency

Moderator: Thierry Allafort-Duverger, MSF-Operational Center Paris

  • Mortality among the Rohingyas in 2017. Sophie Masson
  • Access to health care in North Cameroon. Etienne Gignoux
  • Mental health in Mosul, Iraq. Jihane Ben Farhat
  • Modelling the cholera outbreak in Yemen. Anton Camacho


16h15 – Round table: What can research change?
Moderator: Anne Roca, The Lancet Global Health

Participants

- James Berkley, Kenya Medical Research Institute
- Bernard Opar, Ministry of Health, Uganda
- Natalie Roberts, MSF-Operational Center Paris
- Amadou Sall, Institut Pasteur Dakar

17.00 – Farewell drinks on site, 9th floor Terrace - Institut du Monde Arabe

Abstracts

Classification principale
07.06.2018

Bacterial bloodstream infections in a pediatric hospital in Niger - Langendorf C - Abstract 2018

Classification principale
07.06.2018

Routine antibiotics in the treatment of uncomplicated severe acute malnutrition in Niger - Chokote B - Abstract 2018

Classification principale
07.06.2018

Nutritional support to pregnant women in Niger - Isanaka S - Abstract 2018

Classification principale
07.06.2018

Diagnostic of tuberculosis in children - Bonnet M - Abstract 2018

Classification principale
07.06.2018

Development of diagnostics for pediatric infections - Page AL - Abstract 2018

Classification principale
07.06.2018

Treating Hepatitis C in MSF programs - Loarec A - Abstract 2018

Classification principale
07.06.2018

Introducing two new drugs for resistant tuberculosis - Huerga H - Abstract 2018

Classification principale
07.06.2018

Antibiotic prophylaxis as a response to a meningococcal meningitis outbreak - Coldiron M - Abstract 2018

Classification principale
07.06.2018

Systematic and empirical treatment of tuberculosis in HIV advanced infected patients - Muzoora C - Abstract 2018

Classification principale
07.06.2018

Mortality among the Rohingyas in 2017 - Masson S - Abstract 2018

Classification principale
07.06.2018

Access to health care in North Cameroon - Gignoux E - Abstract 2018

Classification principale
07.06.2018

Mental health in Mosul, Iraq - Ben Farhat J - Abstract 2018

Classification principale
07.06.2018

Modelling the cholera outbreak in Yemen - Camacho A - Abstract 2018

See all

Posters

Classification principale
07.06.2018

Culture conversion and treatment outcomes of a short treatment regimen for multidrug resistant tuberculosis in Mozambique - Bastard M - Poster 2018

Classification principale
07.06.2018

Unravelling the dynamics of hepatitis-E infections in displaced populations: implications for reactive vaccination campaigns - Camacho A - Poster 2018

Classification principale
07.06.2018

Prevalence of parasitemia in an area receiving seasonal malaria chemoprevention - Coldiron M - Poster 2018

Classification principale
07.06.2018

Protective effectiveness of seasonal malaria chemoprevention in Magaria, Niger - Coldiron M - Poster 2018

Classification principale
07.06.2018

Single-dose oral ciprofloxacin prophylaxis as a meningococcal meningitis outbreak response: results of a cluster-randomized trial - Coldiron M - Poster 2018

Classification principale
07.06.2018

Field challenges to measles elimination in the Democratic Republic of Congo - Coulbourn R - Poster 2018

Classification principale
07.06.2018

Reducing the Frequency of Follow up and Task Sharing in the Treatment of Uncomplicated SAM: an evaluation for access-limited and high-burden setting - Isanaka S - Poster 2018

Classification principale
07.06.2018

Community and hospital-acquired invasive bacterial infections in children in Mali: aetiology, antibiotic resistance and clinical outcomes - Langendorf C - Poster 2018

Classification principale
07.06.2018

Cholera diseases burden and circulation of V. cholerae strains in Africa - Luquero F - Poster 2018

Classification principale
07.06.2018

Cholera spatial clustering and the use of case-area targeted interventions - Luquero F - Poster 2018

Classification principale
07.06.2018

Pneumococcal carriage and serotypes distribution pre- and post- PCV10 vaccination campaign in Adjumani refugee camps, Uganda - Nanjebe D - Poster 2018

Classification principale
07.06.2018

Evaluation of measles vaccine in extended controlled temperature conditions - Tang K - Poster 2018

Classification principale
07.06.2018

Retrospective mortality survey, Tshibala and Kalomba Health Zones, Kasai Central, Democratic Republic of Congo (DRC) - Touré B - Poster 2018 (FR)

See all

VIDEOS

Classification principale
12.01.2019

Bacterial bloodstream infections in a pediatric hospital in Niger - Langendorf C - Video 2018

Classification principale
12.01.2019

Routine antibiotics in the treatment of uncomplicated severe acute malnutrition in Niger - Chokote B - Video 2018

Classification principale
15.01.2019

Nutritional support to pregnant women in Niger - Isanaka S - Video 2018

Classification principale
07.06.2018

Diagnostic of tuberculosis in children - Bonnet M - Video 2018

Classification principale
15.01.2019

Development of diagnostics for pediatric infections - Page AL - Video 2018

Classification principale
15.01.2019

Treating Hepatitis C in MSF programs - Loarec A - Video 2018

Classification principale
15.01.2019

Introducing two new drugs for resistant tuberculosis - Huerga H - Video 2018 - Huerga H - Video 2018

Classification principale
15.01.2019

Antibiotic prophylaxis as a response to a meningococcal meningitis outbreak - Coldiron M - Video 2018

Classification principale
15.01.2019

Systematic and empirical treatment of tuberculosis in HIV advanced infected patients - Muzoora C - Video 2018

Classification principale
15.01.2019

Mortality among the Rohingyas in 2017 - Masson S - Video 2018

Classification principale
15.01.2019

Access to health care in North Cameroon - Gignoux E - Video 2018

Classification principale
08.06.2017

Refugees in Greece: violence, mental health and access to information - Ben Farhat J - Video 2017

Classification principale
07.06.2018

Modelling the cholera outbreak in Yemen - Camacho A - Video 2018

See all