Publications

Evaluating the diagnostic accuracy of WHO-recommended treatment decision algorithms for childhood tuberculosis using an individual person dataset: a study protocol.

Abstract

INTRODUCTION: In 2022, the WHO conditionally recommended the use of treatment decision algorithms (TDAs) for treatment decision-making in children 10 years with presumptive tuberculosis (TB), aiming to decrease the substantial case det

Olbrich L Larsson L Dodd PJ Palmer M Nguyen MHTN d'Elbée M Hesseling AC Heinrich N Zar HJ Ntinginya NE Khosa C Nliwasa M Verghese V Bonnet M Wobudeya E Nduna B Moh R Mwanga J Mustapha A Breton G Taguebue JV Borand L Marcy O Chabala C Seddon J van der Zalm MM
BMJ open 2025 Sep 17; 15(9); . doi: 10.1136/bmjopen-2024-094954. Epub 2025 09 17
Child Clinical Decision-Making Tuberculosis

Status and prospects of seasonal malaria chemoprevention among children in Sahelian countries: A systematic review and meta-analysis.

Abstract

In areas with seasonal malaria transmission, seasonal malaria chemoprevention (SMC) involves giving children a three-day course of sulfadoxine-pyrimethamine and amodiaquine once a month during the transmission season.

Djedanem M Salé NM Aminou EYYM Testa J Jambou R
PLOS global public health 2025 ; 5(9); . doi: 10.1371/journal.pgph.0005124. Epub 2025 09 12

Assessing immunization coverage in Southern togo: implications for perennial malaria chemoprevention delivery.

Abstract

BACKGROUND: Malaria remains a major health challenge in sub-Saharan Africa, especially for children under five.

Arikawa S Tchankoni MK Gbeasor-Komlanvi F Atekpe SP Atcha-Oubou T Figueroa-Romero A Orne-Gliemann J Menendez C Gonzalez R Briand V Ekouevi D
BMC public health 2025 Sep 02; 25(1); . doi: 10.1186/s12889-025-24191-0. Epub 2025 09 02
Childhood immunization Children PMC Sub-Saharan africa Togo

Pharmacokinetics of rifampicin and isoniazid in patients with HIV-tuberculosis coinfection receiving efavirenz-based antiretroviral treatment: an ANRS12292-RIFAVIRENZ sub-study.

Abstract

BACKGROUND: Increasing rifampicin dosing is considered a potent strategy for shortening TB treatment duration.

Gelé T Atwine D Baudin E Muyindike W Mworozi K Kyohairwe R Kananura K Logoose S Nyehangane D Nanjebe DKT Furlan V Taburet AM Bonnet M Barrail-Tran A
The Journal of antimicrobial chemotherapy 2025 Aug 29; . doi: 10.1093/jac/dkaf319. Epub 2025 08 29

The challenge of protracted measles outbreaks in Kismayo, Somalia: A mixed-method investigation of measles burden and vaccination coverage during a 2020-2021 outbreak.

Abstract

There was a protracted measles outbreak in Kismayo, Somalia between 2020-2021. The outbreak persisted despite availability of measles containing vaccine (MCV) through Expanded Program on Immunization (EPI) services and reactive vaccination campaigns.

Lau DK Seebacher S Abdi A Ahmed S Nur MB Ciglenecki I Guadarrama A Gignoux E
PLOS global public health 2025 ; 5(8); . doi: 10.1371/journal.pgph.0005143. Epub 2025 08 29

Effect of smoking on drug-resistant tuberculosis treatment outcomes and exploring potential pathways: A multicountry cohort study.

Abstract

People who smoke are at increased risk of unfavorable tuberculosis (TB) treatment outcomes compared with those who do not, but the pathways explaining this effect are unclear.

Romo ML LaHood A Stagg HR Mitnick CD Trevisi L Hewison C Padayachee S Flores EH Oyewusi L Khan PY Huerga H Bastard M Rich ML Tefera GB Rashitov M Kirakosyan O Krisnanda A Toktogonova A Siddiqui MR Gómez-Restrepo C Kotrikadze T Franke MF
medRxiv : the preprint server for health sciences 2025 Aug 24; . doi: 10.1101/2025.08.20.25334077. Epub 2025 08 24
Lost to Follow-Up Multidrug-Resistant Mycobacterium tuberculosis Tobacco Smoking Treatment Adherence and Compliance Tuberculosis

Characterizing treatment adherence trajectories in the endTB multisite cohort of drug-resistant tuberculosis patients: an application of group-based trajectory modelling.

Abstract

BACKGROUND: In tuberculosis (TB) care, adherence is often assessed using a simple 80% threshold, which may overlook meaningful patterns.

Law S Fulcher I Ashraf S Bastard M Docteur W Franke M Guerra D Hewison C Huerga H Khan M Khan P Khan U Kliescikova J Kumsa A Lomtadze N Putri FA Rich ML Seung K Skrahina A Tamirat M Vo LNQ Mitnick CD
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2025 Aug 22; . doi: 10.1093/cid/ciaf467. Epub 2025 08 22
MDR-TB Tuberculosis adherence directly observed therapy group-based trajectory models

Diagnostic performance and kinetics of hepatitis E viral RNA and IgM antibody test positivity in a genotype 1 outbreak in South Sudan.

Abstract

BACKGROUND: Diagnostics are essential for understanding hepatitis E epidemiology, but the field performance of available tests remains unclear.

Koyuncu A Nesbitt R Alvarez C Asilaza KV Wamala J Haile M Gignoux E Albela M Gurley ES Loro FB Biem D Rull M Rumunu J Ciglenecki I Eckerle I Azman AS
The Journal of infectious diseases 2025 Aug 14; . doi: 10.1093/infdis/jiaf436. Epub 2025 08 14
diagnostics hepatitis E hepatitis E virus (HEV)

Clinical outcomes of internal fixation orthopaedic surgery in humanitarian settings: a retrospective cohort study at the Médecins Sans Frontières (MSF) trauma centre in Aden, Yemen.

Abstract

PURPOSE: The Aden Trauma Centre in Yemen, supported by Médecins Sans Frontières (MSF), introduced internal fixation (IF) procedures to address the high burden of fractures as a result of road traffic accidents and conflict-related inju

Malaeb R Hussain T Ayyash F Abdullah A Ahmed HS Abdulrahman K Al Haj A Bin Shahna H Zelikova E Hassanin I Poulet E Herard P Fakhri R
International orthopaedics 2025 Aug 13; . doi: 10.1007/s00264-025-06616-y. Epub 2025 08 13
Bone union Humanitarian settings Internal fixation Orthopedic surgery

Acquisition of Escherichia coli carrying extended-spectrum ß-lactamase and carbapenemase genes by hospitalised children with severe acute malnutrition in Niger.

Abstract

Hospitalisation and routine antibiotic treatment are recommended for children with complicated severe acute malnutrition (SAM) but this may exacerbate antimicrobial resistance.

Sands K Lankapalli AK Lai G Hassan B Portal EA Mathias JA Boostrom I Li M Cook K Premchand-Branker S Jones LS Sayinzonga-Makombe N Isanaka S Kanapathipillai R Mambula C Mouniaman I Langendorf C Walsh TR Spiller OB
Nature communications 2025 Aug 01; 16(1); . doi: 10.1038/s41467-025-61718-w. Epub 2025 08 01