Publications

Efficacy of antimalarial treatment in Guinea: in vivo study of two artemisinin combination therapies in Dabola and molecular markers of resistance to sulphadoxine-pyrimethamine in N'Zérékoré.

Abstract

BACKGROUND: In the last five years, countries have been faced with changing their malaria treatment policy to an artemisinin-based combination therapy (ACT), many with no national data on which to base their decision.

Bonnet M Roper C Félix M Coulibaly L Kankolongo GM Guthmann JP
Malaria journal 2007 May 03; 6 54. doi: 10.1186/1475-2875-6-54. Epub 2007 05 03
O'Brien DP Sauvageot D Olson D Schaeffer M Humblet P Pudjades M Ellman T Zachariah R Szumilin E Arnould L Read T
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2007 May 01; 44(9); 1245-8. doi: 10.1086/513433. Epub 2007 03 28

Relapses of Plasmodium vivax infection usually result from activation of heterologous hypnozoites.

Abstract

BACKGROUND: Relapses originating from hypnozoites are characteristic of Plasmodium vivax infections. Thus, reappearance of parasitemia after treatment can result from relapse, recrudescence, or reinfection.

Imwong M Snounou G Pukrittayakamee S Tanomsing N Kim JR Nandy A Guthmann JP Nosten F Carlton J Looareesuwan S Nair S Sudimack D Day NP Anderson TJ White NJ
The Journal of infectious diseases 2007 Apr 01; 195(7); 927-33. doi: 10.1086/512241. Epub 2007 02 26

Could nutritional rehabilitation at home complement or replace centre-based therapeutic feeding programmes for severe malnutrition?

Abstract

To measure the success rate of three different strategies used in Médecins Sans Frontières large-scale therapeutic nutritional rehabilitation programme in Niger, we analysed three cohorts of severely malnourished patients in terms of daily weight gain,

Gaboulaud V Dan-Bouzoua N Brasher C Fedida G Gergonne B Brown V
Journal of tropical pediatrics 2007 Feb ; 53(1); 49-51. doi: 10.1093/tropej/fml052. Epub 2006 10 09

Molecular genotyping in a malaria treatment trial in Uganda - unexpected high rate of new infections within 2 weeks after treatment.

Abstract

Polymerase chain reaction (PCR) genotyping of malaria parasites in drug efficacy trials helps differentiate reinfections from recrudescences.

Mugittu K Priotto G Guthmann JP Kiguli J Adjuik M Snounou G Beck HP Mshinda H Olliaro PL Taylor WR
Tropical medicine & international health : TM & IH 2007 Feb ; 12(2); 219-23. doi: 10.1111/j.1365-3156.2007.01813.x. Epub 2007 03 15

Drug policy for visceral leishmaniasis: a cost-effectiveness analysis.

Abstract

OBJECTIVE: To facilitate the choice of the best visceral leishmaniasis (VL) treatment strategy for first-line health services in (VL)-endemic areas, we compared in a formal decision analysis the cost and the cost-effectiveness of the d

Vanlerberghe V Diap G Guerin PJ Meheus F Gerstl S Van der Stuyft P Boelaert M
Tropical medicine & international health : TM & IH 2007 Feb ; 12(2); 274-83. doi: 10.1111/j.1365-3156.2006.01782.x. Epub 2007 03 15

Response to highly active antiretroviral therapy among severely immuno-compromised HIV-infected patients in Cambodia.

Abstract

BACKGROUND: HAART efficacy was evaluated in a real-life setting in Phnom Penh (Médecins Sans Frontières programme) among severely immuno-compromised patients.

Madec Y Laureillard D Pinoges L Fernandez M Prak N Ngeth C Moeung S Song S Balkan S Ferradini L Quillet C Fontanet A
AIDS (London, England) 2007 Jan 30; 21(3); 351-9. doi: 10.1097/QAD.0b013e328012c54f. Epub 2007 05 07

Unacceptably high mortality related to measles epidemics in Niger, Nigeria, and Chad.

Abstract

BACKGROUND: Despite the comprehensive World Health Organization (WHO)/United Nations Children's Fund (UNICEF) measles mortality-reduction strategy and the Measles Initiative, a partnership of international organizations supporting meas

Grais RF Dubray C Gerstl S Guthmann JP Djibo A Nargaye KD Coker J Alberti KP Cochet A Ihekweazu C Nathan N Payne L Porten K Sauvageot D Schimmer B Fermon F Burny ME Hersh BS Guerin PJ
PLoS medicine 2007 Jan ; 4(1); e16. doi: 10.1371/journal.pmed.0040016. Epub 2007 08 24