Publications

Guthmann JP Ampuero J Fortes F van Overmeir C Gaboulaud V Tobback S Dunand J Saraiva N Gillet P Franco J Denoncin A van Herp M Balkan S Dujardin JC D'Alessandro U Legros D
Transactions of the Royal Society of Tropical Medicine and Hygiene 2005 Jul ; 99(7); 485-92. doi: 10.1016/j.trstmh.2004.11.010. Epub 2005 09 22

Malaria in the Nuba Mountains of Sudan: baseline genotypic resistance and efficacy of the artesunate plus sulfadoxine-pyrimethamine and artesunate plus amodiaquine combinations.

Abstract

Both northern and southern Sudan are deploying artemisinin-based combinations against uncomplicated Plasmodium falciparum malaria (artesunate+sulfadoxine-pyrimethamine [AS+SP] in the north, artesunate+amodiaquine [AS+AQ] in the south).

Hamour S Melaku Y Keus K Wambugu J Atkin S Montgomery J Ford N Hook C Checchi F
Transactions of the Royal Society of Tropical Medicine and Hygiene 2005 Jul ; 99(7); 548-54. doi: 10.1016/j.trstmh.2004.10.003. Epub 2005 09 22

Selection strength and hitchhiking around two anti-malarial resistance genes.

Abstract

Neutral mutations may hitchhike to high frequency when they are situated close to sites under positive selection, generating local reductions in genetic diversity.

Nash D Nair S Mayxay M Newton PN Guthmann JP Nosten F Anderson TJ
Proceedings. Biological sciences 2005 Jun 07; 272(1568); 1153-61. doi: 10.1098/rspb.2004.3026. Epub 2005 11 21

Supervised versus unsupervised intake of six-dose artemether-lumefantrine for treatment of acute, uncomplicated Plasmodium falciparum malaria in Mbarara, Uganda: a randomised trial.

Abstract

BACKGROUND: The six-dose regimen of artemether-lumefantrine is effective and is among combination therapies prioritised to replace antimalarials that no longer work in Africa.

Piola P Fogg C Bajunirwe F Biraro S Grandesso F Ruzagira E Babigumira J Kigozi I Kiguli J Kyomuhendo J Ferradini L Taylor W Checchi F Guthmann JP
Lancet (London, England) ; 365(9469); 1467-73. doi: 10.1016/S0140-6736(05)66416-1. Epub 2005 05 03
Guthmann JP Sauvageot D De Filippi L Burny ME Brown V
Lancet (London, England) ; 365(9463); 934. doi: 10.1016/S0140-6736(05)71071-0. Epub 2005 04 08

Effectiveness of mass oral cholera vaccination in Beira, Mozambique.

Abstract

BACKGROUND: New-generation, orally administered cholera vaccines offer the promise of improved control of cholera in sub-Saharan Africa.

Lucas ME Deen JL von Seidlein L Wang XY Ampuero J Puri M Ali M Ansaruzzaman M Amos J Macuamule A Cavailler P Guerin PJ Mahoudeau C Kahozi-Sangwa P Chaignat CL Barreto A Songane FF Clemens JD
The New England journal of medicine 2005 Feb 24; 352(8); 757-67. doi: 10.1056/NEJMoa043323. Epub 2005 02 28

Evidence basis for antimalarial policy change in Sierra Leone: five in vivo efficacy studies of chloroquine, sulphadoxine-pyrimethamine and amodiaquine.

Abstract

OBJECTIVES: To provide nationally relevant information on the antimalarial efficacy of chloroquine (CQ), sulphadoxine-pyrimethamine (SP) and amodiaquine (AQ) in Sierra Leone, with a view to updating antimalarial policy in the country.

Checchi F Roddy P Kamara S Williams A Morineau G Wurie AR Hora B Lamotte Nd Baerwaldt T Heinzelmann A Danks A Pinoges L Oloo A Durand R Ranford-Cartwright L Smet M
Tropical medicine & international health : TM & IH 2005 Feb ; 10(2); 146-53. doi: 10.1111/j.1365-3156.2004.01367.x. Epub 2005 03 24

Efficacy and effectiveness of the combination of sulfadoxine/pyrimethamine and a 3-day course of artesunate for the treatment of uncomplicated falciparum malaria in a refugee settlement in Zambia.

Abstract

In the Maheba Refugee Settlement, in the clinics supported by Medecins Sans Frontieres, all children aged up to 5 years with a confirmed diagnosis of uncomplicated falciparum malaria are treated with the combination of sulfadoxine/pyrimethamine (SP) an

Depoortere E Guthmann JP Pressé J Sipilanyambe N Nkandu E Balkan S de Pécoulas PE Legros D
Tropical medicine & international health : TM & IH 2005 Feb ; 10(2); 139-45. doi: 10.1111/j.1365-3156.2004.01363.x. Epub 2005 03 24