Ebola Epidemic description

Monday 18 September 2023 - Updated on Thursday 21 September 2023
During the recent Ebola epidemics, with various actors and MSF sections intervening in complex, ever-evolving contexts spanning diverse, geographically dispersed areas, Epicentre helped coordinate and support epidemiological activities. This included offering technical expertise to MSF epidemiologists deployed in the field and to partners.

Description of the 2022 Ebola outbreak in Uganda

Context

Sudan Virus (SUDV) is one of the five filoviruses of the genus Ebolavirus. In September 2022, an outbreak of SUDV was declared in Uganda, a country that has experienced several Ebola outbreaks over the past two decades.

Methods

Using the line list of cases from the Ministry of Health, we aimed to describe the timeline and geographic spread of SUDV cases during the 2022 outbreak, their demographic features, and case fatality rates, in relation to contextual elements and the operational response.

Results

Three aspects of this outbreak are highlighted and discussed: 1. Population mobility and the geographic spread of SUDV cases, 2. A superspreading event in a small rural town, and 3. The difficulty of early detection of Ebola virus disease (EVD), especially in children. Based on these observations, we raise some operational questions and suggest possible interventions to better cope with the challenges experienced by the healthcare system during Ebola outbreak responses.

Conclusion

Prior to, during, and after Ebola outbreaks, continuing efforts are needed to improve preparedness of the healthcare system for better outbreak control and quality of care.

Video
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Description de l'épidémie d'Ebola de 2022 en Ouganda | Denis Ardiet

Description of the 2018-2020 Ebola outbreak in RDC

Context

On August 1, 2018, the DRC Ministry of Health (MSP) declared the start of the 10th Ebola Virus Disease (EVD) epidemic, linked to the Zaire ebolavirus strain (EBOV). 

Methods

Linelists of cases from the Ministry of Health allowed to analyze the spreading of EBOV cases in relationship with contextual elements, such as the widespread use of Ebola vaccines and introduction of Ebola treatments.

Results

In a region characterized by armed conflict, chronic insecurity and political instability, the epidemic spread to 3 provinces and 29 health zones, infecting a total of 3,464 cases, of which 3,317 confirmed and 146 probable cases. The overall CFR was 65%, with half of the deaths having occurred in the community. 

Conclusions

This unpreceded EBOV epidemic was characterized by many difficulties in implementing control measures, but Ebola vaccines and treatments were demonstrated to be efficient in improving both patients’ survival rate and outbreak control. 

Video
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Description and epidemic control indicators of an Ebola virus disease epidemic in the Democratic Republic of the Congo - Grandesso F - Video 2020

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