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Clinical efficacy of chloroquine or sulfadoxine-pyrimethamine in children under five from south-western Uganda with uncomplicated falciparum malaria.

Legros D Johnson K Houpikian P Makanga M Kabakyenga JK Talisuna AO Taylor WR
Transactions of the Royal Society of Tropical Medicine and Hygiene ; 96(2); 199-201. doi: . Epub 2002 07 09

Abstract

We conducted a 14-day study (during March-May 1998) to assess the efficacy of chloroquine and sulfadoxine-pyrimethamine (SP) for treating uncomplicated Plasmodium falciparum malaria in Uganda. Overall treatment failure rates were 43 (81.1%) of 53 chloroquine recipients and 16 (25.0%) of 64 SP patients. Strategies to improve the life-span of standard and affordable anti-malarial drugs are needed.