Publications

Feasibility and acceptability of using the novel urine-based FujiLAM test to detect tuberculosis: A multi-country mixed-methods study.

Abstract

Background: The novel urine-based FujiLAM test identifies tuberculosis in HIV-positive patients but may be challenging to use at point-of-care (POC).

Chenai Mathabire Rücker S Lissouba P Akinyi M Vicent Lubega A Stewart R Tamayo Antabak N Taremwa Mugisha I Ohler L Macuácua H Atieno M Muyindike W Turyahabwe S Odhiambo Okomo G Mahomed Couto A Musoke M Bossard C Hewison C Ndlovu Z Huerga H
Journal of clinical tuberculosis and other mycobacterial diseases 2022 May ; 27; . doi: 10.1016/j.jctube.2022.100316. Epub 2022 04 25
Diagnostic tests Feasibility studies FujiLAM Low income settings Tuberculosis

SARS-CoV-2 Antibody Prevalence and Population-Based Death Rates, Greater Omdurman, Sudan.

Abstract

In a cross-sectional survey in Omdurman, Sudan, during March-April 2021, we estimated that 54.6% of the population had detectable severe acute respiratory syndrome coronavirus 2 antibodies.

Moser W Fahal MAH Abualas E Bedri S Elsir MT Mohamed MFERO Mahmoud AB Ahmad AII Adam MA Altalib S DafaAllah OA Hmed SA Azman AS Ciglenecki I Gignoux E González A Mwongera C Miranda MA
Emerging infectious diseases 2022 May ; 28(5); . doi: 10.3201/eid2805.211951. Epub 2022 04 25
Abualas E Bedri S COVID-19 Elsir MT Fahal MAH Mohamed MFERO Omdurman SARS-CoV-2 Sudan Sudan. Emerg Infect Dis. 2022 May [date cited]. https://doi.org/10.3201/eid2805.211951 Suggested citation for this article: Moser W antibody et al. SARS-CoV-2 antibody prevalence and population-based death rates excess mortality greater Omdurman respiratory infections seroprevalence severe acute respiratory syndrome coronavirus 2 viruses zoonoses

Prevalence of TB and health-seeking behaviour.

Abstract

No abstract available

Conan N Simons E Ohler L Mbatha M van Cutsem G Huerga H
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2022 May 01; 26(5); . doi: 10.5588/ijtld.22.0001. Epub 2022 05 05

Measuring the unknown: An estimator and simulation study for assessing case reporting during epidemics.

Abstract

The fraction of cases reported, known as 'reporting', is a key performance indicator in an outbreak response, and an essential factor to consider when modelling epidemics and assessing their impact on populations.

Jarvis CI Gimma A Finger F Morris TP Thompson JA le Polain de Waroux O Edmunds WJ Funk S Jombart T
PLoS computational biology 2022 05 ; 18(5); . doi: 10.1371/journal.pcbi.1008800. Epub 2022 05 23

The seasonality of cholera in sub-Saharan Africa: a statistical modelling study.

Abstract

BACKGROUND: Cholera remains a major threat in sub-Saharan Africa (SSA), where some of the highest case-fatality rates are reported.

Perez-Saez J Lessler J Lee EC Luquero FJ Malembaka EB Finger F Langa JP Yennan S Zaitchik B Azman AS
The Lancet. Global health 2022 Apr 21; . doi: 10.1016/S2214-109X(22)00007-9. Epub 2022 04 21

Risk of community- and hospital-acquired bacteremia and profile of antibiotic resistance in children hospitalized with severe acute malnutrition in Niger.

Abstract

OBJECTIVE: To estimate the prevalence and antibiotic resistance profile of community- and hospital-acquired bacteremia among hospitalized children with severe acute malnutrition in Niger.

Andersen CT Langendorf C Garba S Sayinzonga-Makombe N Mambula C Mouniaman I Hanson KE Grais RF Isanaka S
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 2022 Mar 25; . doi: 10.1016/j.ijid.2022.03.047. Epub 2022 03 25
Niger antimicrobial resistance bacteremia community-acquired hospital-acquired nosocomial severe acute malnutrition

Tuberculosis screening among HIV-positive inpatients: a systematic review and individual participant data meta-analysis.

Abstract

BACKGROUND: Since 2011, WHO has recommended that HIV-positive inpatients be routinely screened for tuberculosis with the WHO four-symptom screen (W4SS) and, if screened positive, receive a molecular WHO-recommended rapid diagnostic tes

Dhana A Hamada Y Kengne AP Kerkhoff AD Rangaka MX Kredo T Baddeley A Miller C Gupta-Wright A Fielding K Wood R Huerga H Rücker SCM Heidebrecht C Wilson D Bjerrum S Johansen IS Thit SS Kyi MM Hanson J Barr DA Meintjes G Maartens G
The lancet. HIV 2022 Mar 17; . doi: 10.1016/S2352-3018(22)00002-9. Epub 2022 03 17

Protocol for a phase 3 trial to evaluate the effectiveness and safety of a heterologous, two-dose vaccine for Ebola virus disease in the Democratic Republic of the Congo.

Abstract

INTRODUCTION: Ebola virus disease (EVD) continues to be a significant public health problem in sub-Saharan Africa, especially in the Democratic Republic of the Congo (DRC).

Watson-Jones D Kavunga-Membo H Grais RF Ahuka S Roberts N Edmunds WJ Choi EM Roberts CH Edwards T Camacho A Lees S Leyssen M Spiessens B Luhn K Douoguih M Hatchett R Bausch DG Muyembe JJ
BMJ open 2022 03 08; 12(3); . doi: 10.1136/bmjopen-2021-055596. Epub 2022 03 08
Ebola infectious diseases public health tropical medicine vaccine

Safety and effectiveness outcomes from a 14-country cohort of patients with multi-drug resistant tuberculosis treated concomitantly with bedaquiline, delamanid and other second-line drugs.

Abstract

BACKGROUND: Concomitant use of bedaquiline (Bdq) and delamanid (Dlm) for multi-drug/rifampicin resistant tuberculosis (MDR/RR-TB) has raised concerns about a potentially poor risk-benefit ratio.

Huerga H Khan U Bastard M Mitnick CD Lachenal N Khan PY Seung KJ Melikyan N Ahmed S Rich ML Varaine F Osso E Rashitov M Salahuddin N Salia G Sánchez E Serobyan A Siddiqui MR Tefera DG Vetushko D Yeghiazaryan L Holtzman D Islam S Kumsa A Leblanc GJ Leonovich O Mamsa S Manzur-Ul-Alam M Myint Z Padayachee S Franke MF Hewison C
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2022 Mar 04; . doi: 10.1093/cid/ciac176. Epub 2022 03 04
adverse events combination therapy endTB linezolid

Knowledge, attitudes and practices on childhood TB among healthcare workers.

Abstract

Increasing childhood TB case detection requires the deployment of diagnostic services at peripheral healthcare level. Capacity and readiness of healthcare workers (HCWs) are key to the delivery of innovative approaches.

Joshi B Font H Wobudeya E Nanfuka M Kobusingye A Mwanga-Amumpaire J Natukunda N Turyahabwe S Borand L Mao TE Dim B Ferhi R Moh R Kouakou J Aka Bony R Breton G Mustapha A Matata L Foray L Detjen A Verkuijl S Sekadde M Khosa C Mbassa V Taguebue JV Kwedi Nolna S Bonnet M Marcy O Orne-Gliemann J
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2022 Mar 01; 26(3); 243-251. doi: 10.5588/ijtld.21.0317. Epub 2022 02 24