Publications

Severe acute malnutrition results in lower lumefantrine exposure in children treated with artemether-lumefantrine for uncomplicated malaria.

Abstract

Severe acute malnutrition (SAM) has been reported to be associated with increased malaria morbidity in Sub-Saharan African children and may affect the pharmacology of antimalarial drugs.

Chotsiri P Denoeud-Ndam L Baudin E Guindo O Diawara H Attaher O Smit M Guerin PJ Doumbo OK Wiesner L Barnes KI Hoglund RM Dicko A Etard JF Tarning J
Clinical pharmacology and therapeutics 2019 Jun 01; . doi: 10.1002/cpt.1531. Epub 2019 06 01
Lumefantrine malaria malnutrition non-linear mixed effects modelling population pharmacokinetic-pharmacodynamic model severe acute malnutrition children

Utility of Clinical and Laboratory Decision Rules in Identifying Bacterial Meningitis Among Children with Suspicion of Central Nervous System Infections in a Malaria-Endemic Area, Mbarara, Uganda.

Abstract

Several decision rules combining clinical and biological parameters have been proposed to distinguish bacterial from aseptic meningitis, but have not been evaluated in Africa.

Boum Y Nyehangane D Llosa AE Saliez N Nanjebe D Kemigisha E Charrel RN Baron E Mwanga-Amumpaire J Page AL
The Pediatric infectious disease journal 2019 Jun ; 38(6); e131-e133. doi: 10.1097/INF.0000000000002185. Epub 2019 05 22

Cost-effectiveness of community-based screening and treatment of moderate acute malnutrition in Mali.

Abstract

Introduction: Moderate acute malnutrition (MAM) causes substantial child morbidity and mortality, accounting for 4.4% of deaths and 6.0% of disability-adjusted life years (DALY) lost among children under 5 each year.

Isanaka S Barnhart DA McDonald CM Ackatia-Armah RS Kupka R Doumbia S Brown KH Menzies NA
BMJ global health 2019 ; 4(2); e001227. doi: 10.1136/bmjgh-2018-001227. Epub 2019 04 28
CSB++ Mali PlumpySup Super Cereal corn soy blend cost cost-effectiveness moderate acute malnutrition ready to use supplementary foods

Delayed second dose of oral cholera vaccine administered before high-risk period for cholera transmission: Cholera control strategy in Lusaka, 2016.

Abstract

BACKGROUND: In April 2016, an emergency vaccination campaign using one dose of Oral Cholera Vaccine (OCV) was organized in response to a cholera outbreak that started in Lusaka in February 2016.

Ferreras E Matapo B Chizema-Kawesha E Chewe O Mzyece H Blake A Moonde L Zulu G Poncin M Sinyange N Kasese-Chanda N Phiri C Malama K Mukonka V Cohuet S Uzzeni F Ciglenecki I Danovaro-Holliday MC Luquero FJ Pezzoli L
PloS one 2019 ; 14(8); e0219040. doi: 10.1371/journal.pone.0219040. Epub 2019 08 30

Feasibility of using Determine TB-LAM to diagnose tuberculosis in HIV-positive patients in programmatic conditions: a multisite study.

Abstract

: Determine TB-LAM is a urine-based point-of-care assay for diagnosis of tuberculosis (TB). : To assess the feasibility of using LAM to diagnose TB in adult HIV-positive patients in resource-limited settings.

Mathabire Rucker SC Cossa L Harrison RE Mpunga J Lobo S Kisaka Kimupelenge P Mandar Kol'Ampwe F Amoros Quiles I Molfino L Szumilin E Telnov O Ndlovu Z Huerga H
Global health action 2019 ; 12(1); 1672366. doi: 10.1080/16549716.2019.1672366. Epub 2019 10 15
Lipoarabinomannan diagnosis implementation low income settings tuberculosis

Who is telling the story? A systematic review of authorship for infectious disease research conducted in Africa, 1980-2016.

Abstract

Introduction: Africa contributes little to the biomedical literature despite its high burden of infectious diseases. Global health research partnerships aimed at addressing Africa-endemic disease may be polarised.

Mbaye R Gebeyehu R Hossmann S Mbarga N Bih-Neh E Eteki L Thelma OA Oyerinde A Kiti G Mburu Y Haberer J Siedner M Okeke I Boum Y
BMJ global health 2019 ; 4(5); e001855. doi: 10.1136/bmjgh-2019-001855. Epub 2019 10 18
HIV buruli ulcer clinical trial epidemiology tuberculosis

Stuck in the middle: a systematic review of authorship in collaborative health research in Africa, 2014-2016.

Abstract

Background: Collaborations are often a cornerstone of global health research. Power dynamics can shape if and how local researchers are included in manuscripts.

Hedt-Gauthier BL Jeufack HM Neufeld NH Alem A Sauer S Odhiambo J Boum Y Shuchman M Volmink J
BMJ global health 2019 ; 4(5); e001853. doi: 10.1136/bmjgh-2019-001853. Epub 2019 10 18
academic collaboration decolonizing global health global health research equity

Molecular epidemiology of hepatitis C virus in Cambodia during 2016-2017.

Abstract

In Cambodia, little epidemiological data of hepatitis C virus (HCV) is available. All previous studies were limited to only small or specific populations.

Nouhin J Iwamoto M Prak S Dousset JP Phon K Heng S Kerleguer A Le Paih M Dussart P Maman D Rouet F
Scientific reports 2019 May 13; 9(1); 7314. doi: 10.1038/s41598-019-43785-4. Epub 2019 05 13

Outcomes of Bedaquiline Treatment in Patients with Multidrug-Resistant Tuberculosis.

Abstract

Bedaquiline is recommended by the World Health Organization for the treatment of multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB).

Mbuagbaw L Guglielmetti L Hewison C Bakare N Bastard M Caumes E Fréchet-Jachym M Robert J Veziris N Khachatryan N Kotrikadze T Hayrapetyan A Avaliani Z Schünemann HJ Lienhardt C
Emerging infectious diseases 2019 May ; 25(5); 936-943. doi: 10.3201/eid2505.181823. Epub 2019 04 19
Armenia Asia China Europe France Georgia MDR South Africa TB XDR antimicrobial resistance bacteria bedaquiline extensively drug resistant individual patient data multidrug resistant tuberculosis tuberculosis and other mycobacteria

Plaidoyer contre l'exclusion des francophones dans la recherche en santé mondiale

Abstract

La tenue de l'Africa Health Agenda International Conference (AHAIC) à Kigali (Rwanda) début mars 2019 a été l'occasion d'organiser un atelier de discussion en français qui a permis de recueillir les témoignages de participants francophones sur l'impact

Roca A Boum Y Wachsmuth I
The Lancet Global Health
Francophone Research Scientists Publishing Africa Health Agenda International Conference (AHAIC)