Publications

HIV misdiagnosis in sub-Saharan Africa: performance of diagnostic algorithms at six testing sites.

Abstract

INTRODUCTION: We evaluated the diagnostic accuracy of HIV testing algorithms at six programmes in five sub-Saharan African countries.

Kosack CS Shanks L Beelaert G Benson T Savane A Ng'ang'a A Andre B Zahinda JB Fransen K Page AL
Journal of the International AIDS Society 2017 07 03; 20(1); 21419. doi: 10.7448/IAS.20.1.21419. Epub 2017 11 16
HIV RDT algorithm diagnostic misdiagnosis test

Trends in one-year cumulative incidence of death between 2005 and 2013 among patients initiating antiretroviral therapy in Uganda.

Abstract

Recent ecological data demonstrate improving outcomes for HIV-infected people in sub-Saharan Africa. Recently, Uganda has experienced a resurgence in HIV incidence and prevalence, but trends in HIV-related deaths have not been well described.

Bebell LM Siedner MJ Musinguzi N Boum Y Bwana BM Muyindike W Hunt PW Martin JN Bangsberg DR
International journal of STD & AIDS 2017 07 ; 28(8); 800-807. doi: 10.1177/0956462416671431. Epub 2016 09 20
Africa Death HIV antiretroviral antiretroviral therapy clinical outcomes early mortality

Drivers for Rift Valley fever emergence in Mayotte: A Bayesian modelling approach.

Abstract

Rift Valley fever (RVF) is a major zoonotic and arboviral hemorrhagic fever. The conditions leading to RVF epidemics are still unclear, and the relative role of climatic and anthropogenic factors may vary between ecosystems.

Métras R Fournié G Dommergues L Camacho A Cavalerie L Mérot P Keeling MJ Cêtre-Sossah C Cardinale E Edmunds WJ
PLoS neglected tropical diseases 2017 Jul ; 11(7); e0005767. doi: 10.1371/journal.pntd.0005767. Epub 2017 07 21

Ciprofloxacin for contacts of cases of meningococcal meningitis as an epidemic response: study protocol for a cluster-randomized trial.

Abstract

BACKGROUND: Epidemics of meningococcal meningitis are common in the "African meningitis belt." Current response strategies include reactive vaccination campaigns, which are often organized too late to have maximal impact.

Coldiron ME Alcoba G Ciglenecki I Hitchings M Djibo A Page AL Langendorf C Grais RF
Trials 2017 06 24; 18(1); 294. doi: 10.1186/s13063-017-2028-y. Epub 2017 06 24
Ciprofloxacin Drug resistance, bacterial Epidemics Meningitis, meningococcal Neisseria meningitidis Niger

Aetiology and Outcomes of Suspected Infections of the Central Nervous System in Children in Mbarara, Uganda.

Abstract

Infections of the central nervous system (CNS) are severe conditions, leading to neurological sequelae or death. Knowledge of the causative agents is essential to develop guidelines for case management in resource-limited settings.

Page AL Boum Ii Y Kemigisha E Salez N Nanjebe D Langendorf C Aberrane S Nyehangane D Nackers F Baron E Charrel R Mwanga-Amumpaire J
Scientific reports 2017 06 02; 7(1); 2728. doi: 10.1038/s41598-017-02741-w. Epub 2017 06 02

High Hepatitis E Seroprevalence Among Displaced Persons in South Sudan.

Abstract

AbstractLarge protracted outbreaks of hepatitis E virus (HEV) have been documented in displaced populations in Africa over the past decade though data are limited outside these exceptional settings.

Azman AS Bouhenia M Iyer AS Rumunu J Laku RL Wamala JF Rodriguez-Barraquer I Lessler J Gignoux E Luquero FJ Leung DT Gurley ES Ciglenecki I
The American journal of tropical medicine and hygiene 2017 Jun ; 96(6); 1296-1301. doi: 10.4269/ajtmh.16-0620. Epub 2017 08 23

Antimicrobial-resistant infections among postpartum women at a Ugandan referral hospital.

Abstract

INTRODUCTION: Puerperal sepsis causes 10% of maternal deaths in Africa, but prospective studies on incidence, microbiology and antimicrobial resistance are lacking.

Bebell LM Ngonzi J Bazira J Fajardo Y Boatin AA Siedner MJ Bassett IV Nyehangane D Nanjebe D Jacquemyn Y van Geertruyden JP Mwanga-Amumpaire J Bangsberg DR Riley LE Boum Y
PloS one 2017 ; 12(4); e0175456. doi: 10.1371/journal.pone.0175456. Epub 2017 04 13

Retrospective mortality among refugees from the Central African Republic arriving in Chad, 2014.

Abstract

BACKGROUND: The Central African Republic has known long periods of instability. In 2014, following the fall of an interim government installed by the Séléka coalition, a series of violent reprisals occurred.

Coldiron ME Roederer T Llosa AE Bouhenia M Madi S Sury L Neuman M Porten K
Conflict and health 2017 ; 11 7. doi: 10.1186/s13031-017-0110-4. Epub 2017 05 15
Central African Republic Chad Exposure to violence Mortality Refugees Violence War crimes