Publications

Grais RF Ashley EA White NJ
Science (New York, N.Y.) 2008 Jun 27; 320(5884); 1718. doi: 10.1126/science.320.5884.1718a. Epub 2008 07 15

Bleach sedimentation: an opportunity to optimize smear microscopy for tuberculosis diagnosis in settings of high prevalence of HIV.

Abstract

BACKGROUND: The purpose of the study was to evaluate the performance and feasibility of tuberculosis diagnosis by sputum microscopy after bleach sedimentation, compared with by conventional direct smear microscopy, in a setting of high

Bonnet M Ramsay A Githui W Gagnidze L Varaine F Guerin PJ
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2008 Jun 01; 46(11); 1710-6. doi: 10.1086/587891. Epub 2008 07 21

Immunogenicity of fractional doses of tetravalent a/c/y/w135 meningococcal polysaccharide vaccine: results from a randomized non-inferiority controlled trial in Uganda.

Abstract

BACKGROUND: Neisseria meningitidis serogroup A is the main causative pathogen of meningitis epidemics in sub-Saharan Africa. In recent years, serogroup W135 has also been the cause of epidemics.

Guerin PJ Naess LM Fogg C Rosenqvist E Pinoges L Bajunirwe F Nabasumba C Borrow R Frøholm LO Ghabri S Batwala V Twesigye R Aaberge IS Røttingen JA Piola P Caugant DA
PLoS neglected tropical diseases 2008 ; 2(12); e342. doi: 10.1371/journal.pntd.0000342. Epub 2008 12 02

Use of Lot Quality Assurance Sampling (LQAS) to estimate vaccination coverage helps guide future vaccination efforts.

Abstract

Inadequate evaluation of vaccine coverage after mass vaccination campaigns, such as used in national measles control programmes, can lead to inappropriate public health responses.

Alberti KP Guthmann JP Fermon F Nargaye KD Grais RF
Transactions of the Royal Society of Tropical Medicine and Hygiene 2008 Mar ; 102(3); 251-4. doi: 10.1016/j.trstmh.2007.10.015. Epub 2008 10 27

Treatment of severe malnutrition with 2-day intramuscular ceftriaxone vs 5-day amoxicillin.

Abstract

BACKGROUND: Systemic antibiotics are routinely prescribed for severe acute malnutrition (SAM). However, there is no consensus regarding the most suitable regimen.

Dubray C Ibrahim SA Abdelmutalib M Guerin PJ Dantoine F Belanger F Legros D Pinoges L Brown V
Annals of tropical paediatrics 2008 Mar ; 28(1); 13-22. doi: 10.1179/146532808X270635. Epub 2008 07 22

Population pharmacokinetics of piperaquine after two different treatment regimens with dihydroartemisinin-piperaquine in patients with Plasmodium falciparum malaria in Thailand.

Abstract

The population pharmacokinetics of piperaquine in adults and children with uncomplicated Plasmodium falciparum malaria treated with two different dosage regimens of dihydroartemisinin-piperaquine were characterized.

Tarning J Ashley EA Lindegardh N Stepniewska K Phaiphun L Day NP McGready R Ashton M Nosten F White NJ
Antimicrobial agents and chemotherapy 2008 Mar ; 52(3); 1052-61. doi: 10.1128/AAC.00955-07. Epub 2008 01 07

The dynamics of measles in sub-Saharan Africa.

Abstract

Although vaccination has almost eliminated measles in parts of the world, the disease remains a major killer in some high birth rate countries of the Sahel.

Ferrari MJ Grais RF Bharti N Conlan AJ Bjørnstad ON Wolfson LJ Guerin PJ Djibo A Grenfell BT
Nature 2008 Feb 07; 451(7179); 679-84. doi: 10.1038/nature06509. Epub 2008 03 12

Time is of the essence: exploring a measles outbreak response vaccination in Niamey, Niger.

Abstract

The current World Health Organization recommendations for response during measles epidemics focus on case management rather than outbreak response vaccination (ORV) campaigns, which may occur too late to impact morbidity and mortality and have a high c

Grais RF Conlan AJ Ferrari MJ Djibo A Le Menach A Bjørnstad ON Grenfell BT
Journal of the Royal Society, Interface 2008 Jan 06; 5(18); 67-74. doi: 10.1098/rsif.2007.1038. Epub 2008 03 04