Publications

Artesunate + amodiaquine and artesunate + sulphadoxine-pyrimethamine for treatment of uncomplicated malaria in Democratic Republic of Congo: a clinical trial with determination of sulphadoxine and pyrimethamine-resistant haplotypes.

Abstract

We undertook a trial of artesunate + amodiaquine (AS + AQ) and artesunate + sulphadoxine-pyrimethamine (AS + SP) in 180 children of age 6-59 months with uncomplicated malaria in Democratic Republic of Congo.

Swarthout TD van den Broek IV Kayembe G Montgomery J Pota H Roper C
Tropical medicine & international health : TM & IH 2006 Oct ; 11(10); 1503-11. doi: 10.1111/j.1365-3156.2006.01710.x. Epub 2006 10 24

Are rapid population estimates accurate? A field trial of two different assessment methods.

Abstract

Emergencies resulting in large-scale displacement often lead to populations resettling in areas where basic health services and sanitation are unavailable. To plan relief-related activities quickly, rapid population size estimates are needed.

Grais RF Coulombier D Ampuero J Lucas ME Barretto AT Jacquier G Diaz F Balandine S Mahoudeau C Brown V
Disasters 2006 Sep ; 30(3); 364-76. doi: 10.1111/j.0361-3666.2005.00326.x. Epub 2006 09 26

Supervised versus unsupervised antimalarial treatment with six-dose artemether-lumefantrine: pharmacokinetic and dosage-related findings from a clinical trial in Uganda.

Abstract

BACKGROUND: A six-dose antimalarial regimen of artemether-lumefantrine (A/L) may soon become one of the most widely used drug combination in Africa, despite possible constraints with adherence and poor absorption due to inadequate nutr

Checchi F Piola P Fogg C Bajunirwe F Biraro S Grandesso F Ruzagira E Babigumira J Kigozi I Kiguli J Kyomuhendo J Ferradini L Taylor WR Guthmann JP
Malaria journal 2006 Jul 19; 5 59. doi: 10.1186/1475-2875-5-59. Epub 2006 07 19

Low efficacy of the combination artesunate plus amodiaquine for uncomplicated falciparum malaria among children under 5 years in Kailahun, Sierra Leone.

Abstract

OBJECTIVE: In 2004, Sierra Leone adopted artesunate plus amodiaquine as first-line antimalarial treatment.

Grandesso F Hagerman A Kamara S Lam E Checchi F Balkan S Scollo G Durand R Guthmann JP
Tropical medicine & international health : TM & IH 2006 Jul ; 11(7); 1017-21. doi: 10.1111/j.1365-3156.2006.01655.x. Epub 2006 08 24

High efficacy of two artemisinin-based combinations (artesunate + amodiaquine and artemether + lumefantrine) in Caala, Central Angola.

Abstract

In April 2004, 137 children 6-59 months of age with uncomplicated Plasmodium falciparum (Pf) malaria (Caala, Central Angola) were randomized to receive either artemether-lumefantrine (Coartem) or artesunate + amodiaquine (ASAQ).

Guthmann JP Cohuet S Rigutto C Fortes F Saraiva N Kiguli J Kyomuhendo J Francis M Noël F Mulemba M Balkan S
The American journal of tropical medicine and hygiene 2006 Jul ; 75(1); 143-5. doi: . Epub 2006 08 18

High mortality associated with an outbreak of hepatitis E among displaced persons in Darfur, Sudan.

Abstract

BACKGROUND: Hepatitis E virus (HEV) causes acute onset of jaundice and a high case-fatality ratio in pregnant women.

Boccia D Guthmann JP Klovstad H Hamid N Tatay M Ciglenecki I Nizou JY Nicand E Guerin PJ
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2006 Jun 15; 42(12); 1679-84. doi: 10.1086/504322. Epub 2006 05 12