Publications

Death rates from malaria epidemics, Burundi and Ethiopia.

Abstract

Death rates exceeded emergency thresholds at 4 sites during epidemics of Plasmodium falciparum malaria in Burundi (2000-2001) and in Ethiopia (2003-2004).

Guthmann JP Bonnet M Ahoua L Dantoine F Balkan S van Herp M Tamrat A Legros D Brown V Checchi F
Emerging infectious diseases 2007 Jan ; 13(1); 140-3. doi: 10.3201/eid1301.060546. Epub 2007 04 18

Three drug combinations for late-stage Trypanosoma brucei gambiense sleeping sickness: a randomized clinical trial in Uganda.

Abstract

OBJECTIVES: Our objective was to compare the efficacy and safety of three drug combinations for the treatment of late-stage human African trypanosomiasis caused by Trypanosoma brucei gambiense.

Priotto G Fogg C Balasegaram M Erphas O Louga A Checchi F Ghabri S Piola P
PLoS clinical trials 2006 Dec 08; 1(8); e39. doi: 10.1371/journal.pctr.0010039. Epub 2006 12 08

Pharyngeal carriage of Neisseria meningitidis in 2-19-year-old individuals in Uganda.

Abstract

In southern Uganda, only sporadic cases of serogroup A meningococcal disease have been reported since 2000.

Caugant DA Fogg C Bajunirwe F Piola P Twesigye R Mutebi F Frøholm LO Rosenqvist E Batwala V Aaberge IS Rottingen JA Guerin PJ
Transactions of the Royal Society of Tropical Medicine and Hygiene 2006 Dec ; 100(12); 1159-63. doi: 10.1016/j.trstmh.2006.01.004. Epub 2006 06 12

Evaluation of three rapid tests for diagnosis of P. falciparum and P. vivax malaria in Colombia.

Abstract

The diagnostic capacity of three malaria rapid diagnostic tests (RDTs), NOW-Malaria-ICT, OptiMAL-IT, and Paracheck-Pf, was evaluated against expert microscopy in Colombia. We tested 896 patients, of whom microscopy confirmed 139 P. falciparum, 279 P.

van den Broek I Hill O Gordillo F Angarita B Hamade P Counihan H Guthmann JP
The American journal of tropical medicine and hygiene 2006 Dec ; 75(6); 1209-15. doi: . Epub 2007 04 04

Efficacy of three artemisinin combination therapies for the treatment of uncomplicated Plasmodium falciparum malaria in the Republic of Congo.

Abstract

BACKGROUND: Presented here are the results of a comparative trial on the efficacy of three artemisinin-based combinations conducted from May to October 2004, in Pool Province, Republic of Congo.

van den Broek I Kitz C Al Attas S Libama F Balasegaram M Guthmann JP
Malaria journal 2006 Nov 24; 5 113. doi: 10.1186/1475-2875-5-113. Epub 2006 11 24

Efficacy of chloroquine and sulfadoxine/pyrimethamine for the treatment of uncomplicated falciparum malaria in Koumantou, Mali.

Abstract

We report the results of an in vivo antimalarial efficacy study with chloroquine (CQ) and sulfadoxine/pyrimethamine (SP) conducted between 2003 and 2004 in Koumantou, southern Mali.

de Radiguès X Diallo KI Diallo M Ngwakum PA Maiga H Djimdé A Sacko M Doumbo O Guthmann JP
Transactions of the Royal Society of Tropical Medicine and Hygiene 2006 Nov ; 100(11); 1013-8. doi: 10.1016/j.trstmh.2006.03.004. Epub 2006 06 12

Methodological issues in the assessment of antimalarial drug treatment: analysis of 13 studies in eight African countries from 2001 to 2004.

Abstract

The objectives of these analyses were to assess the feasibility of the latest WHO recommendations (28-day follow-up with PCR genotyping) for the assessment of antimalarial drug efficacy in vivo and to examine how different statistical approaches affect

Guthmann JP Pinoges L Checchi F Cousens S Balkan S van Herp M Legros D Olliaro P
Antimicrobial agents and chemotherapy 2006 Nov ; 50(11); 3734-9. doi: 10.1128/AAC.01618-05. Epub 2006 09 05

High sensitivity and specificity of the Pastorex latex agglutination test for Neisseria meningitidis serogroup A during a clinical trial in Niger.

Abstract

There is a great need for a rapid diagnostic test to guide vaccine choice during outbreaks of meningococcal meningitis in resource-poor countries.

Borel T Rose AM Guillerm M Sidikou F Gerstl S Djibo A Nathan N Chanteau S Guerin PJ
Transactions of the Royal Society of Tropical Medicine and Hygiene 2006 Oct ; 100(10); 964-9. doi: 10.1016/j.trstmh.2006.03.002. Epub 2006 05 30