Publications

Highly active antiretroviral therapy in resource-poor settings: the experience of Médecins Sans Frontières.

Abstract

We describe the short-term results of highly active antiretroviral therapy (HAART) in seven projects in low and middle income countries. A total of 743 adults were included, and clinical, immunological and virological responses were analysed.

Tassie JM Szumilin E Calmy A Goemaere E
AIDS (London, England) 2003 Sep 05; 17(13); 1995-7. doi: 10.1097/01.aids.0000088165.01779.77. Epub 2003 10 07

A selective sweep driven by pyrimethamine treatment in southeast asian malaria parasites.

Abstract

Malaria parasites (Plasmodium falciparum) provide an excellent system in which to study the genomic effects of strong selection in a recombining eukaryote because the rapid spread of resistance to multiple drugs during the last the past 50 years has be

Nair S Williams JT Brockman A Paiphun L Mayxay M Newton PN Guthmann JP Smithuis FM Hien TT White NJ Nosten F Anderson TJ
Molecular biology and evolution 2003 Sep ; 20(9); 1526-36. doi: 10.1093/molbev/msg162. Epub 2003 06 27

Shigella dysenteriae serotype 1 in west Africa: intervention strategy for an outbreak in Sierra Leone.

Abstract

In November 1999, a Médecins Sans Frontières team based in the southeastern part of Sierra Leone reported an increased number of cases of bloody diarrhoea. Shigella dysenteriae serotype 1 (Sd1) was isolated in the early cases.

Guerin PJ Brasher C Baron E Mic D Grimont F Ryan M Aavitsland P Legros D
Lancet (London, England) 2003 Aug 30; 362(9385); 705-6. doi: 10.1016/S0140-6736(03)14227-4. Epub 2003 10 15

Artesunate and sulfadoxine-pyrimethamine combinations for the treatment of uncomplicated Plasmodium falciparum malaria in Uganda: a randomized, double-blind, placebo-controlled trial.

Abstract

Drug-resistant malaria is spreading in Africa. The few available drugs might be safeguarded if combined with an artemisinin derivative.

Priotto G Kabakyenga J Pinoges L Ruiz A Eriksson T Coussement F Ngambe T Taylor WR Perea W Guthmann JP Olliaro P Legros D
Transactions of the Royal Society of Tropical Medicine and Hygiene ; 97(3); 325-30. doi: . Epub 2004 10 05

Efficacy of artesunate plus chloroquine for the treatment of uncomplicated malaria in children in Burkina Faso: a double-blind, randomized, controlled trial.

Abstract

Chloroquine (CQ)-resistant Plasmodium falciparum is compromising malaria control in Africa. Combining artesunate (AS) with standard antimalarial drugs increases cure rates and may delay drug resistance.

Sirima SB Tiono AB Konaté A Diarra A Castelli F Pinoges L Mugittu K Taylor WR Olliaros PL
Transactions of the Royal Society of Tropical Medicine and Hygiene ; 97(3); 345-9. doi: . Epub 2004 10 05

[Management of cholera epidemics in a refugee camp].

Abstract

Cholera epidemics in refugee camps represent a major public health emergency. In camps, precarious living conditions contribute to the transmission of the vibrio.

Brown V Jacquier G Bachy C Bitar D Legros D
Bulletin de la Societe de pathologie exotique (1990) 2002 Dec ; 95(5); 351-4. doi: . Epub 2003 05 07