Scientific Day 2017

Corps éditorial

Introduction

This year’s program reminds us of several fundamental aspects of Epicentre’s activities with MSF. These include the ambition to provide important information during emergency situations, evaluate the efficacy of care strategies in the field, and propose new areas of work and development for adapting medical practice to different contexts. With this in mind, there will be classic presentations of study results, as well as other, more general presentations, which will stimulate our reflection beyond our activities in the field.

More than 15 years after the introduction of antiretrovirals to African programs for managing patients who are seropositive for HIV, many challenges remain. During the first morning session, we will discuss questions of access and diagnosis, as well as treatment failure in very specific patients, children, and adolescents.

Two very current public health questions will then be discussed from the point of view of research, in order to clear the way for reflection and work. Antibiotic resistance is an area in which Epicentre now has a significant level of experience. Several studies have been implemented: what is planned, and how can these studies guide practice toward more rational prescribing? Importantly, we will see how research into infection prevention and control can help lead to a decrease in antibiotic prescribing.

In the past few years, the response to seasonal peaks in malaria cases has relied on the principle of prophylactic chemotherapy distributed on a large scale. Today, this strategy seems to be called into question and even challenged. We will try to shed light on the issues that are involved based on our experience.

We will begin the afternoon session with presentations on the contribution of epidemiology to program management in emergency situations. Four extremely severe situations will be examined: the consequences of conflicts in northern Nigeria, and in Mosul in Iraq, and the refugee situations in northern Uganda and in Greece.

Our last session, which will be moderated by a pioneer in interventional epidemiology, Dr. Ron Waldman, will illustrate one of the unique aspects of our activities, which is the diversity of study situations. We will thus present a tuberculosis clinical trial, an epidemic investigation in Niger, our continuing work toward developing a scale for measuring psychological stress in children, the extent of the need for new cholera vaccines, and finally, access and diagnosis problems for treating visceral leishmaniasis. These various themes and perspectives, as well as their messages, have one main point in common: they are based on the very real practice of research in which Epicentre is engaged as an actor and not simply as a spectator.


We will finish the day with an address from Dr. John Lawrence, president of the Board of Directors for MSF in the United States, who will give us his point of view on the different forms that innovation can take in our interventional contexts.
 

Programme

8.45 – Welcome and coffee

9.30 – Introductory remarks – Emmanuel Baron

9.45 – Session 1: HIV
Moderator: Fred Eboko, Institut de Recherche pour le Développement

  • Prevalence and linkage to care. Nolwenn Conan
  • Understanding virological failure in adolescents living with HIV in Chiradzulu District, Malawi: evidence from a cross-sectional assessment and a qualitative study. Birgit Schramm
  • Early infant diagnosis: field practices and challenges. David Maman

10.30 – Session 2: Control of infections
Moderator: Tjalling Leenstra, National Institute for Public Health and the Environment (RIVM) 

  • Infection control: prescribe while doing no harm in the era of antibiotic resistance. Céline Langendorf
  • Discussion

11.20 – Coffee break

11.50 – Round table: Malaria

Moderator: Lorenz von Seidlein, Mahidol University

  • When and how to change strategy in a malaria epidemic? Aweil, South Sudan, 2016. Adiya Nadimpalla
  • Seasonal malaria chemoprevention: history, rationale and challenges. Matthew Coldiron

Participants: 
- Christine Jamet, MSF-Operational Center Geneva
- Louis Penali, Institut Pasteur Abidjan
- Martin de Smet, Malaria Working Group

13.00 – Lunch on site

14.30 – Session 3: Contribution of epidemiology in emergency contexts 

Moderator: Mego Terzian, MSF - Operational Centre Paris

  • Borno crisis, Nigeria. Mortality and malnutrition in areas of MSF intervention. Sophie Masson
  • Health assessment in refugee camps around Mosul, Iraq. Mohamad Haidar
  • Health assessment and surveillance in refugee camps in Northern Uganda. Denis Ardiet 
  • Refugees in Greece: violence, mental health and access to information. Jihane Ben-Farhat

15.30 – Coffee break

16.00 – Session 4: Genera
l
Moderator: Ronald Waldman, George Washington University

  • RIFAVIRENZ trial: interaction between high dose rifampicin and efavirenz in pulmonary tuberculosis and HIV co-infection. Maryline Bonnet
  • Rift Valley Fever epidemic in Niger. Aboubacar Soumah
  • Cross-cultural validation of a screening tool for psychological difficulties in children aged 6 to 36 months. Thomas Roederer
  • Oral cholera vaccines: transforming old products into new solutions for neglected populations. Francisco Luquero
  • Barriers to access visceral leishmaniasis diagnosis and care among seasonal workers and farmers in Tigray, Ethiopia. Rebecca Coulborn

16.50 – What’s new in innovation? Keynote speaker: John Lawrence, MSF-USA

17.30 – Farewell drinks on site, 9th floor Terrace - Institut du Monde Arabe

Abstracts

Classification principale
08.06.2017

Prevalence and linkage to care - Conan N - Abstract 2017

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08.06.2017

Understanding virological failure in adolescents living with HIV in Chiradzulu District, Malawi - Schramm B - Abstract 2017

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08.06.2017

Early infant diagnosis: field practices and challenges - Maman D - Abstract 2017

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08.06.2017

Infection control: prescribe while doing no harm in the era of antibiotic resistance - Langendorf C - Abstract 2017

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08.06.2017

When and how to change strategy in a malaria epidemic? Aweil, South Sudan, 2016 - Nadimpalli A - Abstract 2017

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08.06.2017

Seasonal malaria chemoprevention: history, rationale and challenges - Coldiron M - Abstract 2017

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08.06.2017

Borno crisis, Nigeria. Mortality and malnutrition in areas of MSF intervention - Masson S - Abstract 2017

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08.06.2017

Health assessment in refugee camps around Mosul, Iraq - Haidar M - Abstract 2017

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08.06.2017

Health assessment and surveillance in refugee camps in Northern Uganda - Ardiet D - Abstract 2017

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08.06.2017

Refugees in Greece: violence, mental health and access to information - Ben Farhat J - Abstract 2017

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08.06.2017

RIFAVIRENZ trial: interaction between high dose rifampicin and efavirenz in pulmonary tuberculosis and HIV co-infection - Baudin E - Abstract 2017

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08.06.2017

Rift Valley Fever epidemic in Niger - Soumah A - Abstract 2017

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08.06.2017

Cross-cultural validation of a screening tool for psychological difficulties in children aged 6 to 36 months - Roederer T - Abstract 2017

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08.06.2017

Oral cholera vaccines: transforming old products into new solutions for neglected populations - Luquero F - Abstract 2017

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08.06.2017

Barriers to access visceral leishmaniasis diagnosis and care among seasonal workers and farmers in Tigray, Ethiopia - Coulborn R - Abstract 2017

See all

Posters

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08.06.2017

Lower retention in care when ART are initiated with CD4=500 cells /ml - Andrieux-Meyer I - Poster 2017

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08.06.2017

Knowledge of viral load and treatment failure amongst patients on second-line and third-line antiretroviral therapy regimens - Burns R - Poster 2017

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08.06.2017

Outcomes and side effects of patients on ART for more than 10 years in Malawi - Mathabire SC - Poster 2017

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08.06.2017

Viral load monitoring with SAMBA-1, a semi quantitative nearly point-of-care method in Arua, a rural district in Uganda - Nicholas S - Poster 2017

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08.06.2017

Impact of expanded screening and POC on infant diagnosis and ART initiation - Nikuze A - Poster 2017

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08.06.2017

HIV incidence, cascade and testing among mothers in Western Kenya - Nikuze A - Poster 2017

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01.04.2017

Low HCV prevalence among HIV+ individuals in sub-Saharan Africa - Loarec A - Poster 2017

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08.06.2017

Hepatitis C treatment in a primary care clinic in the high HCV burden setting in Karachi, Pakistan - Donchuk D - Poster 2017

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08.06.2017

High fatality in low weight children related to supratherapeutic doses of paracetamol in countries with unrestricted access to medication - Haidar M - Poster 2017

See all

Videos

Classification principale
08.06.2017

Prevalence and linkage to care - Conan N - Video 2017

Classification principale
08.06.2017

Understanding virological failure in adolescents living with HIV in Chiradzulu District, Malawi: evidence from a cross-sectional assessment and a qualitative study - Schramm B - Video 2017

Classification principale
08.06.2017

Early infant diagnosis: field practices and challenges - Maman D - Video 2017

Classification principale
08.06.2017

Infection control: prescribe while doing no harm in the era of antibiotic resistance - Langendorf C - Video 2017

Classification principale
08.06.2017

When and how to change strategy in a malaria epidemic? Aweil, South Sudan, 2016 - Nadimpalli A - Video 2017

Classification principale
08.06.2017

Seasonal malaria chemoprevention: history, rationale and challenges - Coldiron M - Video 2017

Classification principale
08.06.2017

Borno crisis, Nigeria. Mortality and malnutrition in areas of MSF intervention - Masson S - Video 2017

Classification principale
08.06.2017

Health assessment in refugee camps around Mosul, Iraq - Haidar M - Video 2017

Classification principale
08.06.2017

Health assessment and surveillance in refugee camps in Northern Uganda - Ardiet D - Video 2017

Classification principale
08.06.2017

Refugees in Greece: violence, mental health and access to information - Ben Farhat J - Video 2017

Classification principale
08.06.2017

RIFAVIRENZ trial: interaction between high dose rifampicin and efavirenz in pulmonary tuberculosis and HIV co-infection - Baudin E - Video 2017

Classification principale
08.06.2017

Rift Valley Fever epidemic in Niger - Soumah A - Video 2017 (FR)

Classification principale
08.06.2017

Cross-cultural validation of a screening tool for psychological difficulties in children aged 6 to 36 months - Roederer T - Video 2017

Classification principale
08.06.2017

Oral cholera vaccines: transforming old products into new solutions for neglected populations - Luquero F - Video 2017

Classification principale
08.06.2017

Barriers to access visceral leishmaniasis diagnosis and care among seasonal workers and farmers in Tigray, Ethiopia - Coulborn R - Video 2017

See all