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S. Isanaka

Sheila Isanaka

Titre du poste
Epidemiologist
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Corps éditorial

Sheila Isanaka conducts large-scale epidemiological studies in complex settings using both observational and randomized designs to inform practice and policy in global nutrition.  Working with Epicentre since 2011, Sheila’s work has focused on the study of severe acute malnutrition (SAM), informing practice around diagnosis, estimation, treatment and prevention. Over 52 million children worldwide suffer from acute malnutrition, with 875,000 deaths in children < 5 years annually attributable to this condition.  Her work also spreads more widely across disciplines to explore the interaction between malnutrition and infectious disease and the role of maternal nutrition in child health and development.

Analysis of Postdischarge Interventions for Children Treated for Moderate or Severe Wasting, Growth Faltering or Failure, or Edema: A Systematic Review.

Journal Reference: JAMA network open 2023 May 01; 6(5); . doi: 10.1001/jamanetworkopen.2023.15077. Epub 2023 05 01

Risk of community- and hospital-acquired bacteremia and profile of antibiotic resistance in children hospitalized with severe acute malnutrition in Niger.

Journal Reference: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 2022 Mar 25; . doi: 10.1016/j.ijid.2022.03.047. Epub 2022 03 25

Burden and risk factors for relapse following successful treatment of uncomplicated severe acute malnutrition in young children: Secondary analysis from a randomised trial in Niger.

Journal Reference: Maternal & child nutrition 2022 Jul 21; . doi: 10.1111/mcn.13400. Epub 2022 07 21

Impact and cost-effectiveness of rotavirus vaccination in Niger: a modelling study evaluating alternative rotavirus vaccines.

Journal Reference: BMJ open 2022 Oct 05; 12(10); . doi: 10.1136/bmjopen-2022-061673. Epub 2022 10 05

Effectiveness of a monthly schedule of follow-up for the treatment of uncomplicated severe acute malnutrition in Sokoto, Nigeria: A cluster randomized crossover trial.

Journal Reference: PLoS medicine 2022 Mar ; 19(3); e1003923. doi: 10.1371/journal.pmed.1003923. Epub 2022 03 01

Cost-effectiveness of routine versus indicated antibiotic therapy in the management of severe wasting in children.

Journal Reference: Cost effectiveness and resource allocation : C/E 2022 Aug 03; 20(1); . doi: 10.1186/s12962-022-00374-z. Epub 2022 08 03

Cost-effectiveness of monthly follow-up for the treatment of uncomplicated severe acute malnutrition: An economic evaluation of a randomized controlled trial.

Journal Reference: PLOS global public health 2022 ; 2(12); . doi: 10.1371/journal.pgph.0001189. Epub 2022 12 09

Cost-effectiveness of routine versus indicated antibiotic therapy in the management of severe wasting in children.

Journal Reference: Cost effectiveness and resource allocation : C/E 2022 Aug 03; 20(1); . doi: 10.1186/s12962-022-00374-z. Epub 2022 08 03

Prenatal supplementation with multiple micronutrient supplements or medium-quantity lipid-based nutrient supplements has limited effects on child growth up to 24 months in rural Niger: a secondary analysis of a cluster randomized trial.

Journal Reference: The American journal of clinical nutrition 2021 Dec 06; . doi: 10.1093/ajcn/nqab404. Epub 2021 12 06

A feasibility study using mid-upper arm circumference as the sole anthropometric criterion for admission and discharge in the outpatient treatment for severe acute malnutrition.

Journal Reference: BMC nutrition 2021 Aug 12; 7(1); 47. doi: 10.1186/s40795-021-00448-w. Epub 2021 08 12

Improving estimates of the burden of severe wasting: analysis of secondary prevalence and incidence data from 352 sites.

Journal Reference: BMJ global health 2021 03 ; 6(3); . doi: 10.1136/bmjgh-2020-004342. Epub 2021 06 24

Immunogenicity of an oral rotavirus vaccine administered with prenatal nutritional support in Niger: A cluster randomized clinical trial.

Journal Reference: PLoS medicine 2021 Aug ; 18(8); e1003720. doi: 10.1371/journal.pmed.1003720. Epub 2021 08 10

Rotavirus vaccine efficacy up to 2 years of age and against diverse circulating rotavirus strains in Niger: Extended follow-up of a randomized controlled trial.

Journal Reference: PLoS medicine 2021 Jul ; 18(7); e1003655. doi: 10.1371/journal.pmed.1003655. Epub 2021 07 02

Conceptualizing factors impacting nutrition services coverage of treatment for acute malnutrition in children - an application of the in Niger.

Journal Reference: Public health nutrition 2021 Oct 08; 1-21. doi: 10.1017/S1368980021004286. Epub 2021 10 08

Exploring the relationships between wasting and stunting among a cohort of children under two years of age in Niger.

Journal Reference: BMC public health 2021 Sep 21; 21(1); 1713. doi: 10.1186/s12889-021-11689-6. Epub 2021 09 21

An exploratory qualitative study of caregivers' knowledge, perceptions and practices related to hospital hygiene in rural Niger.

Journal Reference: Infection prevention in practice 2021 Sep ; 3(3); 100160. doi: 10.1016/j.infpip.2021.100160. Epub 2021 07 03

Etiology and Incidence of Moderate-to-Severe Diarrhea in Young Children in Niger.

Journal Reference: Journal of the Pediatric Infectious Diseases Society 2021 Sep 01; . doi: 10.1093/jpids/piab080. Epub 2021 09 01

A mixture model to assess the the immunogenicity of an oral rotavirus vaccine among healthy infants in Niger.

Journal Reference: Vaccine 2020 Nov 05; . doi: 10.1016/j.vaccine.2020.10.079. Epub 2020 11 05

Feasibility of engaging caregivers in at-home surveillance of children with uncomplicated severe acute malnutrition.

Journal Reference: Maternal & child nutrition 2020 01 ; 16(1); e12876. doi: 10.1111/mcn.12876. Epub 2019 08 09

Energy needs in the treatment of uncomplicated severe acute malnutrition: Secondary analysis to optimize delivery of ready-to-use therapeutic foods.

Journal Reference: Maternal & child nutrition 2020 Mar 07; e12989. doi: 10.1111/mcn.12989. Epub 2020 03 07

Extended Follow-up From a Randomized Clinical Trial of Routine Amoxicillin in the Treatment of Uncomplicated Severe Acute Malnutrition in Niger.

Journal Reference: JAMA pediatrics 2020 Jan 13; . doi: 10.1001/jamapediatrics.2019.5189. Epub 2020 01 13

Exploring the relationships in prenatal weight gain, birth outcomes, and postnatal growth up to 2 Years of age using a longitudinal cohort in Niger.

Journal Reference: Current Developments in Nutrition; Volume 4, Issue Supplement_2, June 2020; Page 1021, https://doi.org/10.1093/cdn/nzaa054_093

Active and adaptive case finding to estimate therapeutic program coverage for severe acute malnutrition: a capture-recapture study.

Journal Reference: BMC health services research 2019 Dec 16; 19(1); 967. doi: 10.1186/s12913-019-4791-9. Epub 2019 12 16

Cost-effectiveness of community-based screening and treatment of moderate acute malnutrition in Mali.

Journal Reference: BMJ global health 2019 ; 4(2); e001227. doi: 10.1136/bmjgh-2018-001227. Epub 2019 04 28

Linear growth faltering and the role of weight attainment: Prospective analysis of young children recovering from severe wasting in Niger.

Journal Reference: Maternal & child nutrition 2019 Mar 23; e12817. doi: 10.1111/mcn.12817. Epub 2019 03 23

Hand hygiene compliance and environmental contamination with gram-negative bacilli in a rural hospital in Madarounfa, Niger.

Journal Reference: Transactions of the Royal Society of Tropical Medicine and Hygiene 2019 Oct 14; . doi: 10.1093/trstmh/trz070. Epub 2019 10 14

Acceptability and Utilization of Three Nutritional Supplements during Pregnancy: Findings from a Longitudinal, Mixed-Methods Study in Niger.

Journal Reference: Nutrients 2018 Aug 12; 10(8); . doi: 10.3390/nu10081073. Epub 2018 08 12

MUAC as the sole discharge criterion from community-based management of severe acute malnutrition in Burkina Faso.

Journal Reference: Maternal & child nutrition 2018 Sep 08; e12688. doi: 10.1111/mcn.12688. Epub 2018 09 08

Estimating program coverage in the treatment of severe acute malnutrition: a comparative analysis of the validity and operational feasibility of two methods.

Journal Reference: Population health metrics 2018 07 03; 16(1); 11. doi: 10.1186/s12963-018-0167-3. Epub 2018 07 03

Malaria and Nutritional Status Among Children With Severe Acute Malnutrition in Niger: A Prospective Cohort Study.

Journal Reference: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2018 Sep 14; 67(7); 1027-1034. doi: 10.1093/cid/ciy207. Epub 2018 11 14

Determinants of dietary practices during pregnancy: A longitudinal qualitative study in Niger.

Journal Reference: Maternal & child nutrition 2018 10 ; 14(4); e12629. doi: 10.1111/mcn.12629. Epub 2018 06 28

Heat-Stable Oral Rotavirus Vaccine.

Journal Reference: The New England journal of medicine 2017 07 20; 377(3); 302. doi: 10.1056/NEJMc1705793. Epub 2017 07 24

Outpatient treatment of severe acute malnutrition: response to treatment with a reduced schedule of therapeutic food distribution.

Journal Reference: The American journal of clinical nutrition 2017 05 ; 105(5); 1191-1197. doi: 10.3945/ajcn.116.148064. Epub 2017 04 12

Efficacy of a Low-Cost, Heat-Stable Oral Rotavirus Vaccine in Niger.

Journal Reference: The New England journal of medicine 2017 03 23; 376(12); 1121-1130. doi: 10.1056/NEJMoa1609462. Epub 2017 04 28

Safety of a heat-stable rotavirus vaccine among children in Niger: Data from a phase 3, randomized, double-blind, placebo-controlled trial.

Journal Reference: Vaccine 2018 06 14; 36(25); 3674-3680. doi: 10.1016/j.vaccine.2018.05.023. Epub 2018 05 08

Cost analysis of the treatment of severe acute malnutrition in West Africa.

Journal Reference: Maternal & child nutrition 2017 10 ; 13(4); . doi: 10.1111/mcn.12398. Epub 2016 12 05

Improving Estimates of Numbers of Children With Severe Acute Malnutrition Using Cohort and Survey Data.

Journal Reference: American journal of epidemiology 2016 12 15; 184(12); 861-869. doi: 10.1093/aje/kww129. Epub 2016 11 17

Routine Amoxicillin for Uncomplicated Severe Acute Malnutrition in Children.

Journal Reference: The New England journal of medicine 2016 Feb 04; 374(5); 444-53. doi: 10.1056/NEJMoa1507024. Epub 2016 02 12

Comparison of Clinical Characteristics and Treatment Outcomes of Children Selected for Treatment of Severe Acute Malnutrition Using Mid Upper Arm Circumference and/or Weight-for-Height Z-Score.

Journal Reference: PloS one 2015 ; 10(9); e0137606. doi: 10.1371/journal.pone.0137606. Epub 2015 09 16

Bridging the gap from knowledge to delivery in the control of childhood diarrhoea.

Journal Reference: Bulletin of the World Health Organization 2012 Sep 01; 90(9); 635-635A. doi: 10.2471/BLT.12.109504. Epub 2013 02 27

Thinking outside the hospital for effective paediatric care: The Médecins Sans Frontières viewpoint.

Journal Reference: Journal of paediatrics and child health 2012 Dec ; 48(12); 1053-5. doi: 10.1111/jpc.12001. Epub 2013 06 07

Estimates of the duration of untreated acute malnutrition in children from Niger.

Journal Reference: American journal of epidemiology 2011 Apr 15; 173(8); 932-40. doi: 10.1093/aje/kwq436. Epub 2011 03 04

Reducing wasting in young children with preventive supplementation: a cohort study in Niger.

Journal Reference: Pediatrics 2010 Aug ; 126(2); e442-50. doi: 10.1542/peds.2009-2814. Epub 2010 07 26

Effect of preventive supplementation with ready-to-use therapeutic food on the nutritional status, mortality, and morbidity of children aged 6 to 60 months in Niger: a cluster randomized trial.

Journal Reference: JAMA 2009 Jan 21; 301(3); 277-85. doi: 10.1001/jama.2008.1018. Epub 2009 01 23

Assessing the impact of the introduction of the World Health Organization growth standards and weight-for-height z-score criterion on the response to treatment of severe acute malnutrition in children: secondary data analysis.

Journal Reference: Pediatrics 2009 Jan ; 123(1); e54-9. doi: 10.1542/peds.2008-1375. Epub 2009 02 06
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