Sheila Isanaka mène des études épidémiologiques à grande échelle dans des contextes complexes en utilisant à la fois des modèles d'observation et des modèles randomisés pour documenter la pratique et la politique dans le domaine de la nutrition mondiale. A Epicentre depuis 2011, le travail de Sheila s'est concentré sur l'étude de la malnutrition aiguë sévère (MAS), aussi bien sur le diagnostic, l'estimation, le traitement et la prévention. Plus de 52 millions d'enfants dans le monde souffrent de malnutrition aiguë, et 875 000 décès d'enfants de moins de 5 ans sont à déplorer. Son travail s'étend également à d'autres disciplines pour explorer l'interaction entre la malnutrition et les maladies infectieuses, ainsi que le rôle de la nutrition maternelle dans la santé et le développement de l'enfant.
Analysis of Postdischarge Interventions for Children Treated for Moderate or Severe Wasting, Growth Faltering or Failure, or Edema: A Systematic Review.
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JAMA network open 2023 May 01; 6(5); . doi: 10.1001/jamanetworkopen.2023.15077. Epub 2023 05 01
Risk of community- and hospital-acquired bacteremia and profile of antibiotic resistance in children hospitalized with severe acute malnutrition in Niger.
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International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 2022 Mar 25; . doi: 10.1016/j.ijid.2022.03.047. Epub 2022 03 25
Burden and risk factors for relapse following successful treatment of uncomplicated severe acute malnutrition in young children: Secondary analysis from a randomised trial in Niger.
Impact and cost-effectiveness of rotavirus vaccination in Niger: a modelling study evaluating alternative rotavirus vaccines.
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BMJ open 2022 Oct 05; 12(10); . doi: 10.1136/bmjopen-2022-061673. Epub 2022 10 05
Effectiveness of a monthly schedule of follow-up for the treatment of uncomplicated severe acute malnutrition in Sokoto, Nigeria: A cluster randomized crossover trial.
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PLoS medicine 2022 Mar ; 19(3); e1003923. doi: 10.1371/journal.pmed.1003923. Epub 2022 03 01
Cost-effectiveness of routine versus indicated antibiotic therapy in the management of severe wasting in children.
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Cost effectiveness and resource allocation : C/E 2022 Aug 03; 20(1); . doi: 10.1186/s12962-022-00374-z. Epub 2022 08 03
Cost-effectiveness of monthly follow-up for the treatment of uncomplicated severe acute malnutrition: An economic evaluation of a randomized controlled trial.
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PLOS global public health 2022 ; 2(12); . doi: 10.1371/journal.pgph.0001189. Epub 2022 12 09
Evaluation of multiple micronutrient supplementation and medium-quantity lipid-based nutrient supplementation in pregnancy on child development in rural Niger: A secondary analysis of a cluster randomized controlled trial.
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PLoS medicine 2022 May ; 19(5); . doi: 10.1371/journal.pmed.1003984. Epub 2022 05 02
Prenatal supplementation with multiple micronutrient supplements or medium-quantity lipid-based nutrient supplements has limited effects on child growth up to 24 months in rural Niger: a secondary analysis of a cluster randomized trial.
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The American journal of clinical nutrition 2021 Dec 06; doi: 10.1093/ajcn/nqab404. Epub 2021 12 06
A feasibility study using mid-upper arm circumference as the sole anthropometric criterion for admission and discharge in the outpatient treatment for severe acute malnutrition.
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BMC nutrition 2021 Aug 12; 7(1); 47. doi: 10.1186/s40795-021-00448-w. Epub 2021 08 12
Improving estimates of the burden of severe wasting: analysis of secondary prevalence and incidence data from 352 sites.
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BMJ global health 2021 03 ; 6(3); doi: 10.1136/bmjgh-2020-004342. Epub 2021 06 24
Immunogenicity of an oral rotavirus vaccine administered with prenatal nutritional support in Niger: A cluster randomized clinical trial.
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PLoS medicine 2021 Aug ; 18(8); e1003720. doi: 10.1371/journal.pmed.1003720. Epub 2021 08 10
Rotavirus vaccine efficacy up to 2 years of age and against diverse circulating rotavirus strains in Niger: Extended follow-up of a randomized controlled trial.
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PLoS medicine 2021 Jul ; 18(7); e1003655. doi: 10.1371/journal.pmed.1003655. Epub 2021 07 02
Conceptualizing factors impacting nutrition services coverage of treatment for acute malnutrition in children – an application of the Three Delays Model in Niger
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Public health nutrition 2021 Oct 08; 1-21. doi: 10.1017/S1368980021004286. Epub 2021 10 08
Exploring the relationships between wasting and stunting among a cohort of children under two years of age in Niger.
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BMC public health 2021 Sep 21; 21(1); 1713. doi: 10.1186/s12889-021-11689-6. Epub 2021 09 21
An exploratory qualitative study of caregivers' knowledge, perceptions and practices related to hospital hygiene in rural Niger.
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Infection prevention in practice 2021 Sep ; 3(3); 100160. doi: 10.1016/j.infpip.2021.100160. Epub 2021 07 03
Etiology and Incidence of Moderate-to-Severe Diarrhea in Young Children in Niger.
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Journal of the Pediatric Infectious Diseases Society 2021 Sep 01; doi: 10.1093/jpids/piab080. Epub 2021 09 01
A mixture model to assess the the immunogenicity of an oral rotavirus vaccine among healthy infants in Niger.
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Vaccine 2020 Nov 05; doi: 10.1016/j.vaccine.2020.10.079. Epub 2020 11 05
Feasibility of engaging caregivers in at-home surveillance of children with uncomplicated severe acute malnutrition.
Estimating program coverage in the treatment of severe acute malnutrition: a comparative analysis of the validity and operational feasibility of two methods.
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Population health metrics 2018 07 03; 16(1); 11. doi: 10.1186/s12963-018-0167-3. Epub 2018 07 03
Malaria and Nutritional Status Among Children With Severe Acute Malnutrition in Niger: A Prospective Cohort Study.
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Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2018 Sep 14; 67(7); 1027-1034. doi: 10.1093/cid/ciy207. Epub 2018 11 14
Determinants of dietary practices during pregnancy: A longitudinal qualitative study in Niger.
Improving Estimates of Numbers of Children With Severe Acute Malnutrition Using Cohort and Survey Data.
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American journal of epidemiology 2016 12 15; 184(12); 861-869. doi: 10.1093/aje/kww129. Epub 2016 11 17
Routine Amoxicillin for Uncomplicated Severe Acute Malnutrition in Children.
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The New England journal of medicine 2016 Feb 04; 374(5); 444-53. doi: 10.1056/NEJMoa1507024. Epub 2016 02 12
Comparison of Clinical Characteristics and Treatment Outcomes of Children Selected for Treatment of Severe Acute Malnutrition Using Mid Upper Arm Circumference and/or Weight-for-Height Z-Score.
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PloS one 2015 ; 10(9); e0137606. doi: 10.1371/journal.pone.0137606. Epub 2015 09 16
Bridging the gap from knowledge to delivery in the control of childhood diarrhoea.
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Bulletin of the World Health Organization 2012 Sep 01; 90(9); 635-635A. doi: 10.2471/BLT.12.109504. Epub 2013 02 27
Thinking outside the hospital for effective paediatric care: The Médecins Sans Frontières viewpoint.
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Journal of paediatrics and child health 2012 Dec ; 48(12); 1053-5. doi: 10.1111/jpc.12001. Epub 2013 06 07
Estimates of the duration of untreated acute malnutrition in children from Niger.
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American journal of epidemiology 2011 Apr 15; 173(8); 932-40. doi: 10.1093/aje/kwq436. Epub 2011 03 04
Reducing wasting in young children with preventive supplementation: a cohort study in Niger.
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Pediatrics 2010 Aug ; 126(2); e442-50. doi: 10.1542/peds.2009-2814. Epub 2010 07 26
Effect of preventive supplementation with ready-to-use therapeutic food on the nutritional status, mortality, and morbidity of children aged 6 to 60 months in Niger: a cluster randomized trial.
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JAMA 2009 Jan 21; 301(3); 277-85. doi: 10.1001/jama.2008.1018. Epub 2009 01 23
Assessing the impact of the introduction of the World Health Organization growth standards and weight-for-height z-score criterion on the response to treatment of severe acute malnutrition in children: secondary data analysis.
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Pediatrics 2009 Jan ; 123(1); e54-9. doi: 10.1542/peds.2008-1375. Epub 2009 02 06