Antimalarial treatments less effective in severely malnourished children

Wednesday 24 July 2019
Malaria Lumefantrine Treatment Effectiveness Malnutrition
Introduction
It calls urgently for further research into optimized dosing regimens for undernourished children.
Bannière
Antimalarial-treatments-malnourished children_1
Corps éditorial

The study in a nutshell

Researchers have found that severe malnutrition is associated with lower exposure to the antimalarial drug lumefantrine in children treated with artemether-lumefantrine, the most common treatment for uncomplicated falciparum malaria. The study, which is the first to specifically address this, has been published in Clinical Pharmacology and Therapeutics. Below is the press release issued on the occasion of the publication of the article related to the study.

Related publication

Severe acute malnutrition results in lower lumefantrine exposure in children treated with artemether-lumefantrine for uncomplicated malaria.

Journal Reference: Clinical pharmacology and therapeutics 2019 Jun 01; (); Array. doi: 10.1002/cpt.1531. Epub 2019 06 01
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Related press release

Classification principale
24.07.2019

Antimalarial treatments less effective in severely malnourished children

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Nutrional diseases

Find out more
Mid-Upper Arm Circumference (MUAC)  is simple method of identifying malnourished young children.