Antimalarial treatments less effective in severely malnourished children
Wednesday 24 July 2019
Malaria
Lumefantrine
Treatment
Effectiveness
Malnutrition
Introduction
It calls urgently for further research into optimized dosing regimens for undernourished children.
Corps éditorial
The study in a nutshell
Researchers have found that severe malnutrition is associated with lower exposure to the antimalarial drug lumefantrine in children treated with artemether-lumefantrine, the most common treatment for uncomplicated falciparum malaria. The study, which is the first to specifically address this, has been published in Clinical Pharmacology and Therapeutics. Below is the press release issued on the occasion of the publication of the article related to the study.
Related publication
Severe acute malnutrition results in lower lumefantrine exposure in children treated with artemether-lumefantrine for uncomplicated malaria.
Journal Reference:
Clinical pharmacology and therapeutics 2019 Jun 01; . doi: 10.1002/cpt.1531. Epub 2019 06 01
Related press release
Classification principale
24.07.2019