Publications

Validity, reliability and ease of use in the field of five rapid tests for the diagnosis of Plasmodium falciparum malaria in Uganda.

Abstract

A study was conducted to measure the overall performance of several rapid diagnostic tests for Plasmodium falciparum infection, in order to select the most appropriate test to be used in the field.

Guthmann JP Ruiz A Priotto G Kiguli J Bonte L Legros D
Transactions of the Royal Society of Tropical Medicine and Hygiene ; 96(3); 254-7. doi: . Epub 2002 09 27

Interleukin (IL)-6, IL-8 and IL-10 in serum and CSF of Trypanosoma brucei gambiense sleeping sickness patients before and after treatment.

Abstract

Serum and cerebrospinal fluid (CSF) concentrations of interleukin (IL)-6, IL-8, IL-10, tumour necrosis factor-alpha and interferon-gamma were determined in 46 Trypanosoma brucei gambiense sleeping sickness patients in DR Congo, before and after treatme

Lejon V Lardon J Kenis G Pinoges L Legros D Bisser S N'Siesi X Bosmans E Büscher P
Transactions of the Royal Society of Tropical Medicine and Hygiene ; 96(3); 329-33. doi: . Epub 2002 09 27

Clinical efficacy of chloroquine or sulfadoxine-pyrimethamine in children under five from south-western Uganda with uncomplicated falciparum malaria.

Abstract

We conducted a 14-day study (during March-May 1998) to assess the efficacy of chloroquine and sulfadoxine-pyrimethamine (SP) for treating uncomplicated Plasmodium falciparum malaria in Uganda.

Legros D Johnson K Houpikian P Makanga M Kabakyenga JK Talisuna AO Taylor WR
Transactions of the Royal Society of Tropical Medicine and Hygiene ; 96(2); 199-201. doi: . Epub 2002 07 09

An outbreak of Rift Valley fever in Northeastern Kenya, 1997-98.

Abstract

In December 1997, 170 hemorrhagic fever-associated deaths were reported in Garissa District, Kenya. Laboratory testing identified evidence of acute Rift Valley fever virus (RVFV).

Woods CW Karpati AM Grein T McCarthy N Gaturuku P Muchiri E Dunster L Henderson A Khan AS Swanepoel R Bonmarin I Martin L Mann P Smoak BL Ryan M Ksiazek TG Arthur RR Ndikuyeze A Agata NN Peters CJ
Emerging infectious diseases 2002 Feb ; 8(2); 138-44. doi: 10.3201/eid0802.010023. Epub 2002 09 06
Brown V Caron P Ford N Clément Cabrol J Pierre Tremblay J Lepec R
Lancet (London, England) 2002 Jan 12; 359(9301); 161. doi: . Epub 2002 02 14

The outbreak and control of Ebola viral haemorrhagic fever in a Ugandan medical school.

Abstract

Uganda has just experienced the largest outbreak of Ebola haemorrhagic fever (EHF) ever recorded. Mbarara University Teaching Hospital (MUTH) is responsible for training approximately one-third of Uganda's doctors.

Bitekyerezo M Kyobutungi C Kizza R Mugeni J Munyarugero E Tirwomwe F Twongyeirwe E Muhindo G Nakibuuka V Nakate M John L Ruiz A Frame K Priotto G Pepper L Kabakyenga J Baingana S Ledo D
Tropical doctor 2002 Jan ; 32(1); 10-5. doi: 10.1177/004947550203200107. Epub 2002 06 07

Shortage of vaccines during a yellow fever outbreak in Guinea.

Abstract

A yellow fever epidemic erupted in Guinea in September, 2000. From Sept 4, 2000, to Jan 7, 2001, 688 instances of the disease and 225 deaths were reported. The diagnosis was laboratory confirmed by IgM detection in more than 40 patients.

Nathan N Barry M Van Herp M Zeller H
Lancet (London, England) ; 358(9299); 2129-30. doi: 10.1016/S0140-6736(01)07185-9. Epub 2002 01 25

Biological data and clinical symptoms as predictors of astrogliosis and neurodegeneration in patients with second-stage Trypanosoma brucei gambiense sleeping sickness.

Abstract

Concentrations of glial fibrillary acidic protein (GFAp) and light subunit neurofilament protein (NFL) in cerebrospinal fluid (CSF) were measured in patients with second-stage Trypanosoma brucei gambiense sleeping sickness.

Lejon V Legros D Rosengren L Gastellu Etchegorry M Büscher P
The American journal of tropical medicine and hygiene 2001 Dec ; 65(6); 931-5. doi: . Epub 2002 01 30

Availability and affordability of treatment for Human African Trypanosomiasis.

Abstract

Human African Trypanosomiasis (HAT) is a re-emerging disease whose usual treatments are becoming less efficient because of the increasing parasite resistance.

Etchegorry MG Helenport JP Pecoul B Jannin J Legros D
Tropical medicine & international health : TM & IH 2001 Nov ; 6(11); 957-9. doi: . Epub 2002 01 16