Publications

Evaluation of multiple micronutrient supplementation and medium-quantity lipid-based nutrient supplementation in pregnancy on child development in rural Niger: A secondary analysis of a cluster randomized controlled trial.

Abstract

BACKGROUND: It is estimated that over 250 million children under 5 years of age in low- and middle-income countries (LMICs) do not reach their full developmental potential.

Sudfeld CR Bliznashka L Salifou A Guindo O Soumana I Adehossi I Langendorf C Grais RF Isanaka S
PLoS medicine 2022 May ; 19(5); . doi: 10.1371/journal.pmed.1003984. Epub 2022 05 02

The seasonality of cholera in sub-Saharan Africa: a statistical modelling study.

Abstract

BACKGROUND: Cholera remains a major threat in sub-Saharan Africa (SSA), where some of the highest case-fatality rates are reported.

Perez-Saez J Lessler J Lee EC Luquero FJ Malembaka EB Finger F Langa JP Yennan S Zaitchik B Azman AS
The Lancet. Global health 2022 Apr 21; . doi: 10.1016/S2214-109X(22)00007-9. Epub 2022 04 21

Risk of community- and hospital-acquired bacteremia and profile of antibiotic resistance in children hospitalized with severe acute malnutrition in Niger.

Abstract

OBJECTIVE: To estimate the prevalence and antibiotic resistance profile of community- and hospital-acquired bacteremia among hospitalized children with severe acute malnutrition in Niger.

Andersen CT Langendorf C Garba S Sayinzonga-Makombe N Mambula C Mouniaman I Hanson KE Grais RF Isanaka S
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 2022 Mar 25; . doi: 10.1016/j.ijid.2022.03.047. Epub 2022 03 25
Niger antimicrobial resistance bacteremia community-acquired hospital-acquired nosocomial severe acute malnutrition

Tuberculosis screening among HIV-positive inpatients: a systematic review and individual participant data meta-analysis.

Abstract

BACKGROUND: Since 2011, WHO has recommended that HIV-positive inpatients be routinely screened for tuberculosis with the WHO four-symptom screen (W4SS) and, if screened positive, receive a molecular WHO-recommended rapid diagnostic tes

Dhana A Hamada Y Kengne AP Kerkhoff AD Rangaka MX Kredo T Baddeley A Miller C Gupta-Wright A Fielding K Wood R Huerga H Rücker SCM Heidebrecht C Wilson D Bjerrum S Johansen IS Thit SS Kyi MM Hanson J Barr DA Meintjes G Maartens G
The lancet. HIV 2022 Mar 17; . doi: 10.1016/S2352-3018(22)00002-9. Epub 2022 03 17

Protocol for a phase 3 trial to evaluate the effectiveness and safety of a heterologous, two-dose vaccine for Ebola virus disease in the Democratic Republic of the Congo.

Abstract

INTRODUCTION: Ebola virus disease (EVD) continues to be a significant public health problem in sub-Saharan Africa, especially in the Democratic Republic of the Congo (DRC).

Watson-Jones D Kavunga-Membo H Grais RF Ahuka S Roberts N Edmunds WJ Choi EM Roberts CH Edwards T Camacho A Lees S Leyssen M Spiessens B Luhn K Douoguih M Hatchett R Bausch DG Muyembe JJ
BMJ open 2022 03 08; 12(3); . doi: 10.1136/bmjopen-2021-055596. Epub 2022 03 08
Ebola infectious diseases public health tropical medicine vaccine

Safety and effectiveness outcomes from a 14-country cohort of patients with multi-drug resistant tuberculosis treated concomitantly with bedaquiline, delamanid and other second-line drugs.

Abstract

BACKGROUND: Concomitant use of bedaquiline (Bdq) and delamanid (Dlm) for multi-drug/rifampicin resistant tuberculosis (MDR/RR-TB) has raised concerns about a potentially poor risk-benefit ratio.

Huerga H Khan U Bastard M Mitnick CD Lachenal N Khan PY Seung KJ Melikyan N Ahmed S Rich ML Varaine F Osso E Rashitov M Salahuddin N Salia G Sánchez E Serobyan A Siddiqui MR Tefera DG Vetushko D Yeghiazaryan L Holtzman D Islam S Kumsa A Leblanc GJ Leonovich O Mamsa S Manzur-Ul-Alam M Myint Z Padayachee S Franke MF Hewison C
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2022 Mar 04; . doi: 10.1093/cid/ciac176. Epub 2022 03 04
adverse events combination therapy endTB linezolid

Growth and CD4 patterns of adolescents living with perinatally acquired HIV worldwide, a CIPHER cohort collaboration analysis.

Abstract

INTRODUCTION: Adolescents living with HIV are subject to multiple co-morbidities, including growth retardation and immunodeficiency.

Jesson J Crichton S Quartagno M Yotebieng M Abrams EJ Chokephaibulkit K Le Coeur S Aké-Assi MH Patel K Pinto J Paul M Vreeman R Davies MA Ben-Farhat J Van Dyke R Judd A Mofenson L Vicari M Seage G Bekker LG Essajee S Gibb D Penazzato M Collins IJ Wools-Kaloustian K Slogrove A Powis K Williams P Matshaba M Thahane L Nyasulu P Lukhele B Mwita L Kekitiinwa-Rukyalekere A Wanless S Goetghebuer T Thorne C Warszawski J Galli L van Rossum AMC Giaquinto C Marczynska M Marques L Prata F Ene L Okhonskaya L Navarro M Frick A Naver L Kahlert C Volokha A Chappell E Pape JW Rouzier V Marcelin A Succi R Sohn AH Kariminia A Edmonds A Lelo P Lyamuya R Ogalo EA Odhiambo FA Haas AD Bolton C Muhairwe J Tweya H Sylla M D'Almeida M Renner L Abzug MJ Oleske J Purswani M Teasdale C Nuwagaba-Biribonwoha H Goodall R Leroy V
Journal of the International AIDS Society 2022 Mar ; 25(3); e25871. doi: 10.1002/jia2.25871. Epub 2022 03 07
CD4 HIV adolescent cohort studies growth perinatally acquired

Effectiveness of a monthly schedule of follow-up for the treatment of uncomplicated severe acute malnutrition in Sokoto, Nigeria: A cluster randomized crossover trial.

Abstract

BACKGROUND: Community-based management of severe acute malnutrition (SAM) involves weekly or biweekly outpatient clinic visits for clinical surveillance and distribution of therapeutic foods.

Hitchings MDT Berthé F Aruna P Shehu I Hamza MA Nanama S Steve-Edemba C Grais RF Isanaka S
PLoS medicine 2022 Mar ; 19(3); e1003923. doi: 10.1371/journal.pmed.1003923. Epub 2022 03 01

Snakebite epidemiology in humans and domestic animals across the Terai region in Nepal: a multicluster random survey.

Abstract

BACKGROUND: Each year, 2 million people worldwide are bitten by snakes, resulting in an estimated 81 000-138 000 deaths.

Alcoba G Sharma SK Bolon I Ochoa C Babo Martins S Subedi M Shah B Ghimire A Gignoux E Luquero F Ruiz de Castañeda R Ray N Chappuis F
The Lancet. Global health 2022 Mar ; 10(3); e398-e408. doi: 10.1016/S2214-109X(22)00028-6. Epub 2022 02 21

Knowledge, attitudes and practices on childhood TB among healthcare workers.

Abstract

Increasing childhood TB case detection requires the deployment of diagnostic services at peripheral healthcare level. Capacity and readiness of healthcare workers (HCWs) are key to the delivery of innovative approaches.

Joshi B Font H Wobudeya E Nanfuka M Kobusingye A Mwanga-Amumpaire J Natukunda N Turyahabwe S Borand L Mao TE Dim B Ferhi R Moh R Kouakou J Aka Bony R Breton G Mustapha A Matata L Foray L Detjen A Verkuijl S Sekadde M Khosa C Mbassa V Taguebue JV Kwedi Nolna S Bonnet M Marcy O Orne-Gliemann J
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2022 Mar 01; 26(3); 243-251. doi: 10.5588/ijtld.21.0317. Epub 2022 02 24