Publications

ENG

Pharmacokinetics of efavirenz in patients on antituberculosis treatment in high human immunodeficiency virus and tuberculosis burden countries: A systematic review.

Abstract

AIMS: Efavirenz (EFV) and rifampicin-isoniazid (RH) are cornerstone drugs in human immunodeficiency virus (HIV)-tuberculosis (TB) coinfection treatment but with complex drug interactions, efficacy and safety challenges.

Authors: Atwine D Bonnet M Taburet AM
Journal Reference: British journal of clinical pharmacology 2018 Aug ; 84(8); 1641-1658. doi: 10.1111/bcp.13600. Epub 2018 05 22
HIV/AIDS < infectious diseases adverse drug reactions antiretrovirals < infectious diseases genetics and pharmacogenetics pharmacokinetics
ENG

HIV Infection and risk of postpartum infection, complications and mortality in rural Uganda.

Abstract

HIV infection may increase risk of postpartum infection and infection-related mortality. We hypothesized that postpartum infection incidence and attributable mortality in Mbarara, Uganda would be higher in HIV-infected than HIV-uninfected women.

Authors: Bebell LM Ngonzi J Siedner MJ Muyindike WR Bwana BM Riley LE Boum Y Bangsberg DR Bassett IV
Journal Reference: AIDS care 2018 Aug ; 30(8); 943-953. doi: 10.1080/09540121.2018.1434119. Epub 2018 02 16
Africa HIV antiretroviral infection pregnancy puerperal sepsis
ENG

Estimating program coverage in the treatment of severe acute malnutrition: a comparative analysis of the validity and operational feasibility of two methods.

Abstract

BACKGROUND: Many health programs can assess coverage using standardized cluster survey methods, but estimating the coverage of nutrition programs presents a special challenge due to low disease prevalence.

Authors: Isanaka S Hedt-Gauthier BL Grais RF Allen BGS
Journal Reference: Population health metrics 2018 07 03; 16(1); 11. doi: 10.1186/s12963-018-0167-3. Epub 2018 07 03
Bayesian conjugate analysis Cluster survey Coverage SQUEAC Severe acute malnutrition Therapeutic feeding program
ENG

Is 6 months of bedaquiline enough? Results from the compassionate use of bedaquiline in Armenia and Georgia.

Abstract

BACKGROUND AND SETTING: Bedaquiline (BDQ) was initially only available through compassionate use programmes.

Authors: Hewison C Bastard M Khachatryan N Kotrikadze T Hayrapetyan A Avaliani Z Kiria N Yegiazaryan L Chumburidze N Kirakosyan O Atshemyan H Qayyum S Lachenal N Varaine F Huerga H
Journal Reference: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2018 Jul 01; 22(7); 766-772. doi: 10.5588/ijtld.17.0840. Epub 2018 06 19
ENG

Sub-national variation in measles vaccine coverage and outbreak risk: a case study from a 2010 outbreak in Malawi.

Abstract

BACKGROUND: Despite progress towards increasing global vaccination coverage, measles continues to be one of the leading, preventable causes of death among children worldwide.

Authors: Kundrick A Huang Z Carran S Kagoli M Grais RF Hurtado N Ferrari M
Journal Reference: BMC public health 2018 Jun 15; 18(1); 741. doi: 10.1186/s12889-018-5628-x. Epub 2018 06 15
Equity Measles Outbreak Vaccination
ENG

Safety of a heat-stable rotavirus vaccine among children in Niger: Data from a phase 3, randomized, double-blind, placebo-controlled trial.

Abstract

BACKGROUND: Rotavirus remains a major cause of diarrhea among children under 5 years of age. The efficacy of RotaSIIL, a pentavalent rotavirus vaccine, was shown in an event-driven trial in Niger.

Authors: Coldiron ME Guindo O Makarimi R Soumana I Matar Seck A Garba S Macher E Isanaka S Grais RF
Journal Reference: Vaccine 2018 06 14; 36(25); 3674-3680. doi: 10.1016/j.vaccine.2018.05.023. Epub 2018 05 08
Adverse event Diarrhea Gastroenteritis Intussusception Niger Rotavirus infection Rotavirus vaccines Safety
ENG

Immunogenicity and Protection From a Single Dose of Internationally Available Killed Oral Cholera Vaccine: A Systematic Review and Metaanalysis.

Abstract

In addition to improved water supply and sanitation, the 2-dose killed oral cholera vaccine (OCV) is an important tool for the prevention and control of cholera.

Authors: Lopez AL Deen J Azman AS Luquero FJ Kanungo S Dutta S von Seidlein L Sack DA
Journal Reference: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2018 Jun 01; 66(12); 1960-1971. doi: 10.1093/cid/cix1039. Epub 2018 11 13
ENG

Access to care for non-communicable diseases in Mosul, Iraq between 2014 and 2017: a rapid qualitative study.

Abstract

During June 2014 to April 2017, the population of Mosul, Iraq lived in a state of increasing isolation from the rest of Iraq due to the city's occupation by the Islamic State group.

Authors: Baxter LM Eldin MS Al Mohammed A Saim M Checchi F
Journal Reference: Conflict and health 2018 ; 12(); 48. doi: 10.1186/s13031-018-0183-8. Epub 2018 12 29
Access to healthcare Conflict Diabetes Humanitarian Hypertension Iraq Non-communicable diseases War
ENG

Field evaluation of near point of care Cepheid GeneXpert HIV-1 Qual for early infant diagnosis.

Abstract

BACKGROUND: Access to point-of-care HIV testing shortens turn-around times, time to diagnosis and reduces loss to follow-up hence minimizing barriers to early linkage to care and treatment among HIV infected infants.

Authors: Opollo VS Nikuze A Ben-Farhat J Anyango E Humwa F Oyaro B Wanjala S Omwoyo W Majiwa M Akelo V Zeh C Maman D
Journal Reference: PloS one 2018 ; 13(12); e0209778. doi: 10.1371/journal.pone.0209778. Epub 2018 12 27
ENG

Impact of "test and treat" recommendations on eligibility for antiretroviral treatment: Cross sectional population survey data from three high HIV prevalence countries.

Abstract

BACKGROUND: Latest WHO guidelines recommend starting HIV-positive individuals on antiretroviral therapy treatment (ART) regardless of CD4 count. We assessed additional impact of adopting new WHO guidelines.

Authors: Chihana ML Huerga H Van Cutsem G Ellman T Wanjala S Masiku C Szumilin E Etard JF Davies MA Maman D
Journal Reference: PloS one 2018 ; 13(11); e0207656. doi: 10.1371/journal.pone.0207656. Epub 2018 11 26