Publications

ENG

Competing risk events in antimalarial drug trials in uncomplicated Plasmodium falciparum malaria: a WorldWide Antimalarial Resistance Network individual participant data meta-analysis.

Abstract

BACKGROUND: Therapeutic efficacy studies in uncomplicated Plasmodium falciparum malaria are confounded by new infections, which constitute competing risk events since they can potentially preclude/pre-empt the detection of subsequent r

Authors:
Journal Reference: Malaria journal 2019 Jul 05; 18(1); 225. doi: 10.1186/s12936-019-2837-4. Epub 2019 07 05
Competing risk event Plasmodium falciparum Treatment efficacy study
ENG

Effectiveness of oral cholera vaccine in preventing cholera among fishermen in Lake Chilwa, Malawi: A case-control study.

Abstract

BACKGROUND: In response to a cholera outbreak among mobile, difficult-to-reach fishermen on Lake Chilwa, Malawi in 2016, a novel vaccine distribution strategy exploited the proven vaccine thermostability.

Authors: Grandesso F Kasambara W Page AL Debes AK M'bang'ombe M Palomares A Lechevalier P Pezzoli L Alley I Salumu L Msyamboza K Sack D Cohuet S Luquero FJ
Journal Reference: Vaccine 2019 Jun 19; 37(28); 3668-3676. doi: 10.1016/j.vaccine.2019.05.044. Epub 2019 05 24
Cholera Effectiveness Hard-to-reach populations Malawi Thermostability Vaccine
ENG

Utility of Clinical and Laboratory Decision Rules in Identifying Bacterial Meningitis Among Children with Suspicion of Central Nervous System Infections in a Malaria-Endemic Area, Mbarara, Uganda.

Abstract

Several decision rules combining clinical and biological parameters have been proposed to distinguish bacterial from aseptic meningitis, but have not been evaluated in Africa.

Authors: Boum Y Nyehangane D Llosa AE Saliez N Nanjebe D Kemigisha E Charrel RN Baron E Mwanga-Amumpaire J Page AL
Journal Reference: The Pediatric infectious disease journal 2019 Jun ; 38(6); e131-e133. doi: 10.1097/INF.0000000000002185. Epub 2019 05 22
ENG

Severe acute malnutrition results in lower lumefantrine exposure in children treated with artemether-lumefantrine for uncomplicated malaria.

Abstract

Severe acute malnutrition (SAM) has been reported to be associated with increased malaria morbidity in Sub-Saharan African children and may affect the pharmacology of antimalarial drugs.

Authors: Chotsiri P Denoeud-Ndam L Baudin E Guindo O Diawara H Attaher O Smit M Guerin PJ Doumbo OK Wiesner L Barnes KI Hoglund RM Dicko A Etard JF Tarning J
Journal Reference: Clinical pharmacology and therapeutics 2019 Jun 01; (); Array. doi: 10.1002/cpt.1531. Epub 2019 06 01
Lumefantrine malaria malnutrition non-linear mixed effects modelling population pharmacokinetic-pharmacodynamic model severe acute malnutrition children
ENG

Molecular epidemiology of hepatitis C virus in Cambodia during 2016-2017.

Abstract

In Cambodia, little epidemiological data of hepatitis C virus (HCV) is available. All previous studies were limited to only small or specific populations.

Authors: Nouhin J Iwamoto M Prak S Dousset JP Phon K Heng S Kerleguer A Le Paih M Dussart P Maman D Rouet F
Journal Reference: Scientific reports 2019 May 13; 9(1); 7314. doi: 10.1038/s41598-019-43785-4. Epub 2019 05 13
ENG

Outcomes of Bedaquiline Treatment in Patients with Multidrug-Resistant Tuberculosis.

Abstract

Bedaquiline is recommended by the World Health Organization for the treatment of multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB).

Authors: Mbuagbaw L Guglielmetti L Hewison C Bakare N Bastard M Caumes E Fréchet-Jachym M Robert J Veziris N Khachatryan N Kotrikadze T Hayrapetyan A Avaliani Z Schünemann HJ Lienhardt C
Journal Reference: Emerging infectious diseases 2019 May ; 25(5); 936-943. doi: 10.3201/eid2505.181823. Epub 2019 04 19
Armenia Asia China Europe France Georgia MDR South Africa TB XDR antimicrobial resistance bacteria bedaquiline extensively drug resistant individual patient data multidrug resistant tuberculosis tuberculosis and other mycobacteria
ENG

Plaidoyer contre l'exclusion des francophones dans la recherche en santé mondiale

Abstract

La tenue de l'Africa Health Agenda International Conference (AHAIC) à Kigali (Rwanda) début mars 2019 a été l'occasion d'organiser un atelier de discussion en français qui a permis de recueillir les témoignages de participants francophones sur l'impact

Authors: Roca A Boum Y Wachsmuth I
Journal Reference: The Lancet Global Health
Francophone Research Scientists Publishing Africa Health Agenda International Conference (AHAIC)
ENG

A screening tool for psychological difficulties in children aged 6 to 36 months: cross-cultural validation in Kenya, Cambodia and Uganda.

Abstract

BACKGROUND: In low-resource settings, the lack of mental health professionals and cross-culturally validated screening instruments complicates mental health care delivery. This is especially the case for very young children.

Authors: Nackers F Roederer T Marquer C Ashaba S Maling S Mwanga-Amumpaire J Muny S Sokeo C Shom V Palha M Lefèbvre P Kirubi BW Kamidigo G Falissard B Moro MR Grais RF
Journal Reference: BMC pediatrics 2019 Apr 12; 19(1); 108. doi: 10.1186/s12887-019-1461-3. Epub 2019 04 12
Cambodia Kenya Low-income population Mental health Preschool children Psychology Screening Uganda Validation