Publications

ENG

Mortality, Morbidity and Health-Seeking Behaviour during the Ebola Epidemic 2014-2015 in Monrovia Results from a Mobile Phone Survey.

Abstract

Between March 2014 and July 2015 at least 10,500 Ebola cases including more than 4,800 deaths occurred in Liberia, the majority in Monrovia. However, official numbers may have underestimated the size of the outbreak.

Authors: Kuehne A Lynch E Marshall E Tiffany A Alley I Bawo L Massaquoi M Lodesani C Le Vaillant P Porten K Gignoux E
Journal Reference: PLoS neglected tropical diseases 2016 08 ; 10(8); e0004899. doi: 10.1371/journal.pntd.0004899. Epub 2016 08 23
ENG

Asymptomatic Plasmodium Infections in Children in Low Malaria Transmission Setting, Southwestern Uganda(1).

Abstract

A survey of asymptomatic children in Uganda showed Plasmodium malariae and P. falciparum parasites in 45% and 55% of microscopy-positive samples, respectively.

Authors: Roh ME Oyet C Orikiriza P Wade M Kiwanuka GN Mwanga-Amumpaire J Parikh S Boum Y
Journal Reference: Emerging infectious diseases 2016 08 ; 22(8); 1494-8. doi: 10.3201/eid2208.160619. Epub 2018 01 08
Africa PCR Plasmodium Uganda asymptomatic infections children malaria microscopy mosquito nets mosquitoes parasite parasitic diseases protozoan infections
ENG

Invasive Infection and Outcomes in a Humanitarian Surgical Burn Program in Haiti.

Abstract

BACKGROUND: Compare to high-income settings, survival in burn units in low-income settings is lower with invasive infections one leading cause of death.

Authors: Murphy RA Nisenbaum L Labar AS Sheridan RL Ronat JB Dilworth K Pena J Kilborn E Teicher C
Journal Reference: World journal of surgery 2016 Jul ; 40(7); 1550-7. doi: 10.1007/s00268-016-3458-5. Epub 2017 02 09
ENG

A Worldwide Map of Plasmodium falciparum K13-Propeller Polymorphisms.

Abstract

BACKGROUND: Recent gains in reducing the global burden of malaria are threatened by the emergence of Plasmodium falciparum resistance to artemisinins. The discovery that mutations in portions of a P.

Authors: Ménard D Khim N Beghain J Adegnika AA Shafiul-Alam M Amodu O Rahim-Awab G Barnadas C Berry A Boum Y Bustos MD Cao J Chen JH Collet L Cui L Thakur GD Dieye A Djallé D Dorkenoo MA Eboumbou-Moukoko CE Espino FE Fandeur T Ferreira-da-Cruz MF Fola AA Fuehrer HP Hassan AM Herrera S Hongvanthong B Houzé S Ibrahim ML Jahirul-Karim M Jiang L Kano S Ali-Khan W Khanthavong M Kremsner PG Lacerda M Leang R Leelawong M Li M Lin K Mazarati JB Ménard S Morlais I Muhindo-Mavoko H Musset L Na-Bangchang K Nambozi M Niaré K Noedl H Ouédraogo JB Pillai DR Pradines B Quang-Phuc B Ramharter M Randrianarivelojosia M Sattabongkot J Sheikh-Omar A Silué KD Sirima SB Sutherland C Syafruddin D Tahar R Tang LH Touré OA Tshibangu-wa-Tshibangu P Vigan-Womas I Warsame M Wini L Zakeri S Kim S Eam R Berne L Khean C Chy S Ken M Loch K Canier L Duru V Legrand E Barale JC Stokes B Straimer J Witkowski B Fidock DA Rogier C Ringwald P Ariey F Mercereau-Puijalon O
Journal Reference: The New England journal of medicine 2016 06 23; 374(25); 2453-64. doi: 10.1056/NEJMoa1513137. Epub 2016 07 13
ENG

Predictive modeling targets thymidylate synthase ThyX in Mycobacterium tuberculosis.

Abstract

There is an urgent need to identify new treatments for tuberculosis (TB), a major infectious disease caused by Mycobacterium tuberculosis (Mtb), which results in 1.5 million deaths each year.

Authors: Djaout K Singh V Boum Y Katawera V Becker HF Bush NG Hearnshaw SJ Pritchard JE Bourbon P Madrid PB Maxwell A Mizrahi V Myllykallio H Ekins S
Journal Reference: Scientific reports 2016 06 10; 6(); 27792. doi: 10.1038/srep27792. Epub 2016 06 10
ENG

A review of antimicrobial resistance in East Africa.

Abstract

BACKGROUND AND OBJECTIVES: Knowledge of local and regional antimicrobial resistance (AMR) is important for clinical decision making.

Authors: Ampaire L Muhindo A Orikiriza P Mwanga-Amumpaire J Bebell L Boum Y
Journal Reference: African journal of laboratory medicine 2016 ; 5(1); 432. doi: 10.4102/ajlm.v5i1.432. Epub 2016 09 15
ENG

Population-Level Effect of Cholera Vaccine on Displaced Populations, South Sudan, 2014.

Abstract

Following mass population displacements in South Sudan, preventive cholera vaccination campaigns were conducted in displaced persons camps before a 2014 cholera outbreak.

Authors: Azman AS Rumunu J Abubakar A West H Ciglenecki I Helderman T Wamala JF Vázquez Ode L Perea W Sack DA Legros D Martin S Lessler J Luquero FJ
Journal Reference: Emerging infectious diseases 2016 06 ; 22(6); 1067-70. doi: 10.3201/eid2206.151592. Epub 2018 01 12
South Sudan Vibrio cholerae bacteria cholera diarrhea displaced persons transmission dynamics vaccine vulnerable populations
ENG

Diagnostic Accuracy of the Small Membrane Filtration Method for Diagnosis of Pulmonary Tuberculosis in a High-HIV-Prevalence Setting.

Abstract

Sputum acid-fast bacilli (AFB) smear microscopy has suboptimal sensitivity but remains the most commonly used laboratory test to diagnose pulmonary tuberculosis (TB).

Authors: Boum Y Kim S Orikiriza P Acuña-Villaorduña C Vinhas S Bonnet M Nyehangane D Mwanga-Amumpaire J Fennelly KP Jones-López EC
Journal Reference: Journal of clinical microbiology 2016 06 ; 54(6); 1520-1527. doi: 10.1128/JCM.00017-16. Epub 2016 03 30
ENG

Target Product Profile for a Diagnostic Assay to Differentiate between Bacterial and Non-Bacterial Infections and Reduce Antimicrobial Overuse in Resource-Limited Settings: An Expert Consensus.

Abstract

Acute fever is one of the most common presenting symptoms globally. In order to reduce the empiric use of antimicrobial drugs and improve outcomes, it is essential to improve diagnostic capabilities.

Authors: Dittrich S Tadesse BT Moussy F Chua A Zorzet A Tängdén T Dolinger DL Page AL Crump JA D'Acremont V Bassat Q Lubell Y Newton PN Heinrich N Rodwell TJ González IJ
Journal Reference: PloS one 2016 ; 11(8); e0161721. doi: 10.1371/journal.pone.0161721. Epub 2016 08 25
ENG
Authors: Jindani A Borgulya G de Patiño IW Gonzales T de Fernandes RA Shrestha B Atwine D Bonnet M Burgos M Dubash F Patel N Checkley AM Harrison TS Mitchison D
Journal Reference: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2016 06 ; 20(6); 832-8. doi: 10.5588/ijtld.15.0577. Epub 2018 02 14