Publications

Efficacy of three artemisinin combination therapies for the treatment of uncomplicated Plasmodium falciparum malaria in the Republic of Congo.

Abstract

BACKGROUND: Presented here are the results of a comparative trial on the efficacy of three artemisinin-based combinations conducted from May to October 2004, in Pool Province, Republic of Congo.

van den Broek I Kitz C Al Attas S Libama F Balasegaram M Guthmann JP
Malaria journal 2006 Nov 24; 5 113. doi: 10.1186/1475-2875-5-113. Epub 2006 11 24

Efficacy of chloroquine and sulfadoxine/pyrimethamine for the treatment of uncomplicated falciparum malaria in Koumantou, Mali.

Abstract

We report the results of an in vivo antimalarial efficacy study with chloroquine (CQ) and sulfadoxine/pyrimethamine (SP) conducted between 2003 and 2004 in Koumantou, southern Mali.

de Radiguès X Diallo KI Diallo M Ngwakum PA Maiga H Djimdé A Sacko M Doumbo O Guthmann JP
Transactions of the Royal Society of Tropical Medicine and Hygiene 2006 Nov ; 100(11); 1013-8. doi: 10.1016/j.trstmh.2006.03.004. Epub 2006 06 12

Methodological issues in the assessment of antimalarial drug treatment: analysis of 13 studies in eight African countries from 2001 to 2004.

Abstract

The objectives of these analyses were to assess the feasibility of the latest WHO recommendations (28-day follow-up with PCR genotyping) for the assessment of antimalarial drug efficacy in vivo and to examine how different statistical approaches affect

Guthmann JP Pinoges L Checchi F Cousens S Balkan S van Herp M Legros D Olliaro P
Antimicrobial agents and chemotherapy 2006 Nov ; 50(11); 3734-9. doi: 10.1128/AAC.01618-05. Epub 2006 09 05

High sensitivity and specificity of the Pastorex latex agglutination test for Neisseria meningitidis serogroup A during a clinical trial in Niger.

Abstract

There is a great need for a rapid diagnostic test to guide vaccine choice during outbreaks of meningococcal meningitis in resource-poor countries.

Borel T Rose AM Guillerm M Sidikou F Gerstl S Djibo A Nathan N Chanteau S Guerin PJ
Transactions of the Royal Society of Tropical Medicine and Hygiene 2006 Oct ; 100(10); 964-9. doi: 10.1016/j.trstmh.2006.03.002. Epub 2006 05 30

Artesunate + amodiaquine and artesunate + sulphadoxine-pyrimethamine for treatment of uncomplicated malaria in Democratic Republic of Congo: a clinical trial with determination of sulphadoxine and pyrimethamine-resistant haplotypes.

Abstract

We undertook a trial of artesunate + amodiaquine (AS + AQ) and artesunate + sulphadoxine-pyrimethamine (AS + SP) in 180 children of age 6-59 months with uncomplicated malaria in Democratic Republic of Congo.

Swarthout TD van den Broek IV Kayembe G Montgomery J Pota H Roper C
Tropical medicine & international health : TM & IH 2006 Oct ; 11(10); 1503-11. doi: 10.1111/j.1365-3156.2006.01710.x. Epub 2006 10 24

Are rapid population estimates accurate? A field trial of two different assessment methods.

Abstract

Emergencies resulting in large-scale displacement often lead to populations resettling in areas where basic health services and sanitation are unavailable. To plan relief-related activities quickly, rapid population size estimates are needed.

Grais RF Coulombier D Ampuero J Lucas ME Barretto AT Jacquier G Diaz F Balandine S Mahoudeau C Brown V
Disasters 2006 Sep ; 30(3); 364-76. doi: 10.1111/j.0361-3666.2005.00326.x. Epub 2006 09 26