Publications

Supervised versus unsupervised antimalarial treatment with six-dose artemether-lumefantrine: pharmacokinetic and dosage-related findings from a clinical trial in Uganda.

Abstract

BACKGROUND: A six-dose antimalarial regimen of artemether-lumefantrine (A/L) may soon become one of the most widely used drug combination in Africa, despite possible constraints with adherence and poor absorption due to inadequate nutr

Checchi F Piola P Fogg C Bajunirwe F Biraro S Grandesso F Ruzagira E Babigumira J Kigozi I Kiguli J Kyomuhendo J Ferradini L Taylor WR Guthmann JP
Malaria journal 2006 Jul 19; 5 59. doi: 10.1186/1475-2875-5-59. Epub 2006 07 19

Low efficacy of the combination artesunate plus amodiaquine for uncomplicated falciparum malaria among children under 5 years in Kailahun, Sierra Leone.

Abstract

OBJECTIVE: In 2004, Sierra Leone adopted artesunate plus amodiaquine as first-line antimalarial treatment.

Grandesso F Hagerman A Kamara S Lam E Checchi F Balkan S Scollo G Durand R Guthmann JP
Tropical medicine & international health : TM & IH 2006 Jul ; 11(7); 1017-21. doi: 10.1111/j.1365-3156.2006.01655.x. Epub 2006 08 24

High efficacy of two artemisinin-based combinations (artesunate + amodiaquine and artemether + lumefantrine) in Caala, Central Angola.

Abstract

In April 2004, 137 children 6-59 months of age with uncomplicated Plasmodium falciparum (Pf) malaria (Caala, Central Angola) were randomized to receive either artemether-lumefantrine (Coartem) or artesunate + amodiaquine (ASAQ).

Guthmann JP Cohuet S Rigutto C Fortes F Saraiva N Kiguli J Kyomuhendo J Francis M Noël F Mulemba M Balkan S
The American journal of tropical medicine and hygiene 2006 Jul ; 75(1); 143-5. doi: . Epub 2006 08 18

High mortality associated with an outbreak of hepatitis E among displaced persons in Darfur, Sudan.

Abstract

BACKGROUND: Hepatitis E virus (HEV) causes acute onset of jaundice and a high case-fatality ratio in pregnant women.

Boccia D Guthmann JP Klovstad H Hamid N Tatay M Ciglenecki I Nizou JY Nicand E Guerin PJ
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2006 Jun 15; 42(12); 1679-84. doi: 10.1086/504322. Epub 2006 05 12

A large outbreak of hepatitis E among a displaced population in Darfur, Sudan, 2004: the role of water treatment methods.

Abstract

BACKGROUND: The conflict in Darfur, Sudan, was responsible for the displacement of 1.8 million civilians. We investigated a large outbreak of hepatitis E virus (HEV) infection in Mornay camp (78,800 inhabitants) in western Darfur.

Guthmann JP Klovstad H Boccia D Hamid N Pinoges L Nizou JY Tatay M Diaz F Moren A Grais RF Ciglenecki I Nicand E Guerin PJ
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2006 Jun 15; 42(12); 1685-91. doi: 10.1086/504321. Epub 2006 05 12

Tuberculosis after HAART initiation in HIV-positive patients from five countries with a high tuberculosis burden.

Abstract

BACKGROUND: HAART reduces tuberculosis (TB) incidence in people living with HIV/AIDS but those starting HAART may develop active TB or subclinical TB may become apparent in the immune reconstitution inflammatory syndrome.

Bonnet MM Pinoges LL Varaine FF Oberhauser BB O'Brien DD Kebede YY Hewison CC Zachariah RR Ferradini LL
AIDS (London, England) 2006 Jun 12; 20(9); 1275-9. doi: 10.1097/01.aids.0000232235.26630.ee. Epub 2006 10 04

Outbreak of tetanus cases following the tsunami in Aceh Province, Indonesia.

Abstract

Aceh Province in Indonesia was the area most severely affected by the tsunami of 26 December 2004. Extensive loss of life, property, and livelihood left a large segment of the population without basic needs and vulnerable to epidemic-prone diseases.

Global public health 2006 ; 1(2); 173-7. doi: 10.1080/17441690600652803. Epub 2009 02 17

High mortality in an internally displaced population in Ituri, Democratic Republic of Congo, 2005: results of a rapid assessment under difficult conditions.

Abstract

The ongoing conflict in Ituri, Democratic Republic of Congo (DRC), has led to more than 50,000 deaths, more than 500,000 displaced civilians and continuing, unacceptably high, mortality since 1999.

Ahoua L Tamrat A Duroch F Grais RF Brown V
Global public health 2006 ; 1(3); 195-204. doi: 10.1080/17441690600681869. Epub 2009 02 17