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Oral cholera vaccine coverage in Goma, Democratic Republic of the Congo, 2022, following 2019-2020 targeted preventative mass campaigns.

Abstract

BACKGROUND: In 2019-2020, preventative Oral Cholera Vaccine campaigns were conducted in 24/32 non-contiguous health areas of Goma, DR Congo.

Briskin E Bateyi Mustafa SH Mahamba R Kabunga D Kubuya J Porten K Akilimali L Okitayemba Welo P Broban A
Vaccine: X 2024 Oct ; 20; . doi: 10.1016/j.jvacx.2024.100555. Epub 2024 09 12
Cholera Democratic Republic of the Congo Oral cholera vaccine Targeted vaccination Vaccine coverage survey

Evaluation of hydroxychloroquine or chloroquine for the prevention of COVID-19 (COPCOV): A double-blind, randomised, placebo-controlled trial.

Abstract

BACKGROUND: Hydroxychloroquine (HCQ) has proved ineffective in treating patients hospitalised with Coronavirus Disease 2019 (COVID-19), but uncertainty remains over its safety and efficacy in chemoprevention.

Schilling WHK Mukaka M Callery JJ Llewelyn MJ Cruz CV Dhorda M Ngernseng T Waithira N Ekkapongpisit M Watson JA Chandna A Nelwan EJ Hamers RL Etyang A Beg MA Sow S Yavo W Allabi AC Basnyat B Sharma SK Amofa-Sekyi M Yonga P Adler A Yuentrakul P Cope T Thaipadungpanit J Rienpradub P Imwong M Abdad MY Blacksell SD Tarning J Goudjo FF Dossou AD Konaté-Touré A Assi SB Ouffoué K Nasronudin N Rachman BE Romadhon PZ Dewanto DD Heryana MO Novi T Pasaribu AP Mutiara M Nasution MPR Khairunnisa K Dalimunthe FA Airlangga E Fahrezzy A Subronto Y Ananda NR Rahardjani M Rimainar A Lucinde RK Timbwa M Onyango OE Agutu C Akech S Hamaluba M Kipyego J Ngachi O Haidara FC Traoré OY Diarra F Khanal B Dahal P Shrestha S Rijal S Kabore Y Adehossi E Guindo O Qamar FN Kazi AM Woodrow CJ Laird S Cheeba M Ayles H Cheah PY Taylor WRJ Batty EM Chotivanich K Pukrittayakamee S Phumratanaprapin W von Seidlein L Dondorp A Day NPJ White NJ
PLoS medicine 2024 Sep ; 21(9); . doi: 10.1371/journal.pmed.1004428. Epub 2024 09 12

Prevalence and Factors Associated with transfusion-transmissible infections among blood donors in Arua regional blood bank, Uganda.

Abstract

BACKGROUND: Blood transfusion services play a very key role in modern health care service delivery. About 118.5 million blood donations were collected globally in 2022.

Cwinyaai N Opio D Kajumbula H Zalwango JF Akunzirwe R Okello T Francis A
BMC infectious diseases 2024 Sep 06; 24(1); . doi: 10.1186/s12879-024-09838-4. Epub 2024 09 06
Blood donor Seropositive blood donor Transfusion-transmissible infections (TTIs) Voluntary donor

Evaluation of centralised and decentralised models of care during the 2020 Ebola Virus Disease outbreak in Equateur Province, Democratic Republic of the Congo: A brief report.

Abstract

BACKGROUND: Traditionally in the Democratic Republic of the Congo (DRC), centralised Ebola treatment centres (ETCs) have been set exclusively for Ebola virus disease (EVD) case management during outbreaks.

Lampaert E Nsio Mbeta J Nair D Mashako M De Weggheleire A Sprecher A M Coulborn R Ahuka-Mundeke S
F1000Research 2024 ; 13; . doi: 10.12688/f1000research.150755.2. Epub 2024 08 28
Central Africa Decentralized care Ebola Epidemic response Operational Research Outbreak SORT IT Viral Haemorrhagic Fever

Impact of postpartum maternal fever or hypothermia on newborn and early infant illness and death in Southwestern Uganda.

Abstract

BACKGROUND: Deaths occurring during the neonatal period contribute close to half of under-five mortality rate (U5MR); over 80% of these deaths occur in low- and middle-income countries (LMICs).

Mwanga-Amumpaire J Adong J Arinaitwe R Nanjebe D Orikiriza P Ngonzi J Boum Y Bebell LM
BMC pregnancy and childbirth 2024 Aug 27; 24(1); . doi: 10.1186/s12884-024-06775-7. Epub 2024 08 27
Africa Mother Neonate Outcome Pregnancy

Effectiveness of rVSV-ZEBOV vaccination during the 2018–20 Ebola virus disease epidemic in the Democratic Republic of the Congo: a retrospective test-negative study.

Abstract

BACKGROUND: The recombinant vesicular stomatitis virus–Zaire Ebola virus (rVSV-ZEBOV) vaccine is the only WHO prequalified vaccine recommended for use to respond to outbreaks of Ebola virus (species Zaire ebolavirus) by WHO's Strategic

Sophie Meakin Justus Nsio Anton Camacho Richard Kitenge Rebecca M Coulborn Etienne Gignoux et al.
The Lancet Infectious Disease. August 20, 2024. doi: 10.1016/S1473-3099(24)00419-5
Ebola virus disease Vaccination Ervebo Vaccine effectiveness Test-negative

Assessing post-abortion care using the WHO quality of care framework for maternal and newborn health: a cross-sectional study in two African hospitals in humanitarian settings.

Abstract

BACKGROUND: Abortion-related complications remain a main cause of maternal mortality. There is little evidence on the availability and quality of post-abortion care (PAC) in humanitarian settings.

Pasquier E Owolabi OO Powell B Fetters T Ngbale RN Lagrou D Fotheringham C Schulte-Hillen C Chen H Williams T Moore AM Adame Gbanzi MC Debeaudrap P Filippi V Benova L Degomme O
Reproductive health 2024 Aug 05; 21(1); . doi: 10.1186/s12978-024-01835-9. Epub 2024 08 05
Abortion Central African Republic Hospital Humanitarian Maternal health Nigeria Postabortion care Quality of care

Spatiotemporal Modeling of Cholera, Uvira, Democratic Republic of the Congo, 2016-2020.

Abstract

We evaluated the spatiotemporal clustering of rapid diagnostic test-positive cholera cases in Uvira, eastern Democratic Republic of the Congo.

Ratnayake R Knee J Cumming O Saidi JM Rumedeka BB Finger F Azman AS Edmunds WJ Checchi F Gallandat K
Emerging infectious diseases 2024 Aug ; 30(8); . doi: 10.3201/eid3008.231137. Epub 2024 07 23
Democratic Republic of the Congo Vibrio cholerae bacteria cholera disease clusters outbreaks prevention AND control spatiotemporal modeling transmission dynamics

The first line. Study on population of caregivers in contact with epidemic patients in the Sahel, the case of SARS-CoV-2.

Abstract

The health systems of countries in the South and the North have been directly affected by the COVID-19 pandemic. Healthcare workers have paid a high price.

Hamidou Lazoumar Ramatoulaye Karidio Diori Ibrahim Mahamadou Almahamoudou Maiga Zeinabou Alhassane Fakani Aboutalib Aliane François Comlan Aida Sylviane et al.
Research Square, 26 July 2024. doi:10.21203/rs.3.rs-4675025/v1
Health sciences/Diseases Health sciences/Risk factors COVID-19 Health workers Serology Vaccination

Immunogenicity of an Extended Dose Interval for the Ad26.ZEBOV, MVA-BN-Filo Ebola Vaccine Regimen in Adults and Children in the Democratic Republic of the Congo.

Abstract

During the 2018–2020 Ebola virus disease outbreak in Democratic Republic of the Congo, a phase 3 trial of the Ad26.ZEBOV, MVA-BN-Filo Ebola vaccine (DRC-EB-001) commenced in Goma, with participants being offered the two-dose regimen given 56 days apart

Edward Man-Lik Choi Kambale Kasonia Hugo Kavunga-Membo Daniel Mukadi-Bamuleka Aboubacar Soumah Zephyrin Mossoko et al.
Vaccines 2024, 12, 828. doi: 10.3390/vaccines12080828
Ebola Outbreak Democratic Republic of the Congo DRC Vaccine Immunogenicity Interval Ad26.ZEBOV Ad26.ZEBOV Zabdeno MVA-BN-Filo Mvabea