Publications

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Ciprofloxacin for contacts of cases of meningococcal meningitis as an epidemic response: study protocol for a cluster-randomized trial.

Abstract

BACKGROUND: Epidemics of meningococcal meningitis are common in the "African meningitis belt." Current response strategies include reactive vaccination campaigns, which are often organized too late to have maximal impact.

Coldiron ME Alcoba G Ciglenecki I Hitchings M Djibo A Page AL Langendorf C Grais RF
Trials 2017 06 24; 18(1); 294. doi: 10.1186/s13063-017-2028-y. Epub 2017 06 24
Ciprofloxacin Drug resistance, bacterial Epidemics Meningitis, meningococcal Neisseria meningitidis Niger

Aetiology and Outcomes of Suspected Infections of the Central Nervous System in Children in Mbarara, Uganda.

Abstract

Infections of the central nervous system (CNS) are severe conditions, leading to neurological sequelae or death. Knowledge of the causative agents is essential to develop guidelines for case management in resource-limited settings.

Page AL Boum Ii Y Kemigisha E Salez N Nanjebe D Langendorf C Aberrane S Nyehangane D Nackers F Baron E Charrel R Mwanga-Amumpaire J
Scientific reports 2017 06 02; 7(1); 2728. doi: 10.1038/s41598-017-02741-w. Epub 2017 06 02

High Hepatitis E Seroprevalence Among Displaced Persons in South Sudan.

Abstract

AbstractLarge protracted outbreaks of hepatitis E virus (HEV) have been documented in displaced populations in Africa over the past decade though data are limited outside these exceptional settings.

Azman AS Bouhenia M Iyer AS Rumunu J Laku RL Wamala JF Rodriguez-Barraquer I Lessler J Gignoux E Luquero FJ Leung DT Gurley ES Ciglenecki I
The American journal of tropical medicine and hygiene 2017 Jun ; 96(6); 1296-1301. doi: 10.4269/ajtmh.16-0620. Epub 2017 08 23

Antimicrobial-resistant infections among postpartum women at a Ugandan referral hospital.

Abstract

INTRODUCTION: Puerperal sepsis causes 10% of maternal deaths in Africa, but prospective studies on incidence, microbiology and antimicrobial resistance are lacking.

Bebell LM Ngonzi J Bazira J Fajardo Y Boatin AA Siedner MJ Bassett IV Nyehangane D Nanjebe D Jacquemyn Y van Geertruyden JP Mwanga-Amumpaire J Bangsberg DR Riley LE Boum Y
PloS one 2017 ; 12(4); e0175456. doi: 10.1371/journal.pone.0175456. Epub 2017 04 13

Retrospective mortality among refugees from the Central African Republic arriving in Chad, 2014.

Abstract

BACKGROUND: The Central African Republic has known long periods of instability. In 2014, following the fall of an interim government installed by the Séléka coalition, a series of violent reprisals occurred.

Coldiron ME Roederer T Llosa AE Bouhenia M Madi S Sury L Neuman M Porten K
Conflict and health 2017 ; 11 7. doi: 10.1186/s13031-017-0110-4. Epub 2017 05 15
Central African Republic Chad Exposure to violence Mortality Refugees Violence War crimes

Evaluation of a chest radiograph reading and recording system for tuberculosis in a HIV-positive cohort.

Abstract

AIM: To assess the impact of introducing a chest radiograph reading and recording system (CRRS) with a short training session, on the accuracy and inter-reader variability of tuberculosis (TB) interpretation of chest radiographs (CXRs)

Kosack CS Spijker S Halton J Bonnet M Nicholas S Chetcuti K Mesic A Brant WE Joekes E Andronikou S
Clinical radiology 2017 Jun ; 72(6); 519.e1-519.e9. doi: 10.1016/j.crad.2017.01.008. Epub 2017 02 21

Surveillance of HIV-1 pol transmitted drug resistance in acutely and recently infected antiretroviral drug-naïve persons in rural western Kenya.

Abstract

HIV-1 transmitted drug resistance (TDR) is of increasing public health concern in sub-Saharan Africa with the rollout of antiretroviral (ARV) therapy.

Onywera H Maman D Inzaule S Auma E Were K Fredrick H Owiti P Opollo V Etard JF Mukui I Kim AA Zeh C
PloS one 2017 ; 12(2); e0171124. doi: 10.1371/journal.pone.0171124. Epub 2017 02 08

Evaluation of the SD Bioline TB Ag MPT64 test for identification of complex from liquid cultures in Southwestern Uganda.

Abstract

BACKGROUND: To confirm presence of complex, some tuberculosis culture laboratories still rely on para-nitrobenzoic acid (PNB), a traditional technique that requires sub-culturing of clinical isolates and two to three weeks to give res

Orikiriza P Nyehangane D Atwine D Kisakye JJ Kassaza K Amumpaire JM Boum Y
African journal of laboratory medicine 2017 ; 6(2); 383. doi: 10.4102/ajlm.v6i2.383. Epub 2017 03 31