Publications

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Population pharmacokinetics of Artemether and dihydroartemisinin in pregnant women with uncomplicated Plasmodium falciparum malaria in Uganda.

Abstract

BACKGROUND: Malaria in pregnancy increases the risk of maternal anemia, abortion and low birth weight. Approximately 85.3 million pregnancies occur annually in areas with Plasmodium falciparum transmission.

Tarning J Kloprogge F Piola P Dhorda M Muwanga S Turyakira E Nuengchamnong N Nosten F Day NP White NJ Guerin PJ Lindegardh N
Malaria journal 2012 Aug 22; 11 293. doi: 10.1186/1475-2875-11-293. Epub 2012 08 22

Sequence variation does not confound the measurement of plasma PfHRP2 concentration in African children presenting with severe malaria.

Abstract

BACKGROUND: Plasmodium falciparum histidine-rich protein PFHRP2 measurement is used widely for diagnosis, and more recently for severity assessment in falciparum malaria.

Ramutton T Hendriksen IC Mwanga-Amumpaire J Mtove G Olaosebikan R Tshefu AK Onyamboko MA Karema C Maitland K Gomes E Gesase S Reyburn H Silamut K Chotivanich K Promnares K Fanello CI von Seidlein L Day NP White NJ Dondorp AM Imwong M Woodrow CJ
Malaria journal 2012 Aug 16; 11 276. doi: 10.1186/1475-2875-11-276. Epub 2012 08 16

Response to antiretroviral therapy: improved survival associated with CD4 above 500 cells/μl.

Abstract

OBJECTIVE: We investigated the association between immune response and mortality in four HIV African programs supported by Médecins Sans Frontières.

DESIGN: Multicentric retrospective cohort study.

Maman D Pujades-Rodriguez M Nicholas S McGuire M Szumilin E Ecochard R Etard JF
AIDS (London, England) 2012 Jul 17; 26(11); 1393-8. doi: 10.1097/QAD.0b013e328352d054. Epub 2012 12 03

Glucose-6-phosphate dehydrogenase deficiency, chlorproguanil-dapsone with artesunate and post-treatment haemolysis in African children treated for uncomplicated malaria.

Abstract

BACKGROUND: Malaria is a leading cause of mortality, particularly in sub-Saharan African children. Prompt and efficacious treatment is important as patients may progress within a few hours to severe and possibly fatal disease.

Van Malderen C Van Geertruyden JP Machevo S González R Bassat Q Talisuna A Yeka A Nabasumba C Piola P Daniel A Turyakira E Forret P Van Overmeir C van Loen H Robert A D' Alessandro U
Malaria journal 2012 Jul 10; 11 139. doi: 10.1186/1475-2875-11-139. Epub 2012 07 10

Timeliness of clinic attendance is a good predictor of virological response and resistance to antiretroviral drugs in HIV-infected patients.

Abstract

BACKGROUND: Ensuring long-term adherence to therapy is essential for the success of HIV treatment. As access to viral load monitoring and genotyping is poor in resource-limited settings, a simple tool to monitor adherence is needed.

Bastard M Pinoges L Balkan S Szumilin E Ferreyra C Pujades-Rodriguez M
PloS one 2012 ; 7(11); e49091. doi: 10.1371/journal.pone.0049091. Epub 2012 11 07