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Should urine-LAM tests be used in TB symptomatic HIV-positive patients when no CD4 count is available? A prospective observational cohort study from Malawi.


BACKGROUND: Current eligibility criteria for urine lateral-flow-lipoarabinomannan assay (LF-LAM) in ambulatory, HIV-positive patients rely on the CD4 count.

Auteurs: Huerga H Mathabire Rucker SC Bastard M Dimba A Kamba C Amoros I Szumilin E
Référence de l'article: Journal of acquired immune deficiency syndromes (1999) 2019 Oct 16; (); Array. doi: 10.1097/QAI.0000000000002206. Epub 2019 10 16

Evaluation of OMNIgene® SPUTUM and ethanol reagent for preservation of sputum prior to Xpert and culture testing in Uganda.


Xpert MTB/RIF (Xpert) and culture are the most reliable methods for tuberculosis diagnosis but are still poorly accessible in many low resource countries.

Auteurs: Ardizzoni E Orikiriza P Ssuuna C Nyehangane D Gumsboga M Taremwa IM Turyashemererwa E Mwanga-Amumpaire J Langendorf C Bonnet M
Référence de l'article: Journal of clinical microbiology 2019 Oct 16; (); Array. doi: 10.1128/JCM.00810-19. Epub 2019 10 16

Factors influencing participation in an Ebola vaccine trial among front-line workers in Guinea.


BACKGROUND: Alongside the clinical aspects of the immunogenicity and safety trial of an Ebola vaccine deployed among front-line workers, a qualitative study was conducted to describe motivations behind individuals' decisions to partici

Auteurs: Grantz KH Claudot P Kambala M Kouyaté M Soumah A Boum Y Juan-Giner A Jemmy JP Cummings DAT Grais RF
Référence de l'article: Vaccine 2019 Oct 14; (); Array. doi: 10.1016/j.vaccine.2019.09.094. Epub 2019 10 14
Ebola virus disease Guinea Healthcare workers Qualitative Research design rVSV vaccine

Hand hygiene compliance and environmental contamination with gram-negative bacilli in a rural hospital in Madarounfa, Niger.


BACKGROUND: Healthcare-associated infections pose a major, yet often preventable risk to patient safety.

Auteurs: Tang K Berthé F Nackers F Hanson K Mambula C Langendorf C Marquer C Isanaka S
Référence de l'article: Transactions of the Royal Society of Tropical Medicine and Hygiene 2019 Oct 14; (); Array. doi: 10.1093/trstmh/trz070. Epub 2019 10 14
Niger gram-negative bacilli hand hygiene healthcare personnel healthcare-associated infections

What is the best culture conversion prognostic marker for patients treated for multidrug-resistant tuberculosis?


Identification of good prognostic marker for tuberculosis (TB) treatment response is a necessary step on the path towards a surrogate marker to reduce TB trial duration.

Auteurs: Bastard M Sanchez-Padilla E Hayrapetyan A Kimenye K Khurkhumal S Dlamini T Fadul Perez S Telnov A Hewison C Varaine F Bonnet M
Référence de l'article: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2019 Oct 01; 23(10); 1060-1067. doi: 10.5588/ijtld.18.0649. Epub 2019 10 19

Mobile community-based active case-finding for tuberculosis among older populations in rural Cambodia.


To systematically screen older rural populations in Cambodia for tuberculosis (TB) and develop an effective active case-finding (ACF) model for this TB high-risk group.

Auteurs: Camelique O Scholtissen S Dousset JP Bonnet M Bastard M Hewison C
Référence de l'article: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2019 Oct 01; 23(10); 1107-1114. doi: 10.5588/ijtld.18.0611. Epub 2019 10 19

Beyond wasted and stunted-a major shift to fight child undernutrition.


Child undernutrition refers broadly to the condition in which food intake is inadequate to meet a child's needs for physiological function, growth, and the capacity to respond to illness.

Auteurs: Wells JCK Briend A Boyd EM Berkely JA Hall A Isanaka S Webb P Khara T Dolan C
Référence de l'article: The Lancet. Child & adolescent health 2019 Sep 11; (); Array. doi: 10.1016/S2352-4642(19)30244-5. Epub 2019 09 11

Comparative assessment of methicillin resistant Staphylococcus aureus diagnostic assays for use in resource-limited settings.


BACKGROUND: The rise of methicillin-resistant Staphylococcus aureus (MRSA) is a global health concern.

Auteurs: Ayebare A Bebell LM Bazira J Ttendo S Katawera V Bangsberg DR Siedner MJ Firth PG Boum Ii Y
Référence de l'article: BMC microbiology 2019 Aug 22; 19(1); 194. doi: 10.1186/s12866-019-1566-8. Epub 2019 08 22
Africa Carriage Chromogenic agar MRSA Methicillin-resistant Staphylococcus aureus PCR

Measles seroprevalence after reactive vaccination campaigns during the 2015 measles outbreak in four health zones of the former Katanga Province, Democratic Republic of Congo.


BACKGROUND: Measles continues to circulate in the Democratic Republic of Congo, and the country suffered from several important outbreaks over the last 5 years.

Auteurs: Keating P Carrion Martin AI Blake A Lechevalier P Uzzeni F Gignoux E Okonta C Langendorf C Smit S Ahuka S Suchard M Pukuta E Degail MA Hansen L Kibanza-Kyungu J Ciglenecki I Cohuet S
Référence de l'article: BMC public health 2019 Aug 22; 19(1); 1153. doi: 10.1186/s12889-019-7500-z. Epub 2019 08 22
Democratic Republic of Congo Immunity Measles Seroprevalence Vaccination