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Evidence basis for antimalarial policy change in Sierra Leone: five in vivo efficacy studies of chloroquine, sulphadoxine-pyrimethamine and amodiaquine.

Abstract

OBJECTIVES: To provide nationally relevant information on the antimalarial efficacy of chloroquine (CQ), sulphadoxine-pyrimethamine (SP) and amodiaquine (AQ) in Sierra Leone, with a view to updating antimalarial policy in the country.

Checchi F Roddy P Kamara S Williams A Morineau G Wurie AR Hora B Lamotte Nd Baerwaldt T Heinzelmann A Danks A Pinoges L Oloo A Durand R Ranford-Cartwright L Smet M
Tropical medicine & international health : TM & IH 2005 Feb ; 10(2); 146-53. doi: 10.1111/j.1365-3156.2004.01367.x. Epub 2005 03 24

Efficacy and effectiveness of the combination of sulfadoxine/pyrimethamine and a 3-day course of artesunate for the treatment of uncomplicated falciparum malaria in a refugee settlement in Zambia.

Abstract

In the Maheba Refugee Settlement, in the clinics supported by Medecins Sans Frontieres, all children aged up to 5 years with a confirmed diagnosis of uncomplicated falciparum malaria are treated with the combination of sulfadoxine/pyrimethamine (SP) an

Depoortere E Guthmann JP Pressé J Sipilanyambe N Nkandu E Balkan S de Pécoulas PE Legros D
Tropical medicine & international health : TM & IH 2005 Feb ; 10(2); 139-45. doi: 10.1111/j.1365-3156.2004.01363.x. Epub 2005 03 24

Cetyl-pyridinium chloride is useful for isolation of Mycobacterium tuberculosis from sputa subjected to long-term storage.

Abstract

Recovery of Mycobacterium tuberculosis from sputa treated with cetyl-pyridinium chloride (CPC) and stored for 20 +/- 9 days was significantly higher than that from sputa that were untreated and processed by the N-acetyl-L-cisteine-NaOH method.

Pardini M Varaine F Iona E Arzumanian E Checchi F Oggioni MR Orefici G Fattorini L
Journal of clinical microbiology 2005 Jan ; 43(1); 442-4. doi: 10.1128/JCM.43.1.442-444.2005. Epub 2005 03 01

Adherence to a six-dose regimen of artemether-lumefantrine for treatment of uncomplicated Plasmodium falciparum malaria in Uganda.

Abstract

Measuring baseline levels of adherence and identifying risk factors for non-adherence are important steps before the introduction of new antimalarials.

Fogg C Bajunirwe F Piola P Biraro S Checchi F Kiguli J Namiiro P Musabe J Kyomugisha A Guthmann JP
The American journal of tropical medicine and hygiene 2004 Nov ; 71(5); 525-30. doi: . Epub 2005 01 18

Case management of a multidrug-resistant Shigella dysenteriae serotype 1 outbreak in a crisis context in Sierra Leone, 1999-2000.

Abstract

From December 1999 to the end of February 2000, 4218 cases of dysentery were reported in Kenema district, southeastern Sierra Leone, by a Médecins Sans Frontières team operating in this region.

Guerin PJ Brasher C Baron E Mic D Grimont F Ryan M Aavitsland P Legros D
Transactions of the Royal Society of Tropical Medicine and Hygiene 2004 Nov ; 98(11); 635-43. doi: 10.1016/j.trstmh.2004.01.005. Epub 2004 12 06

In vivo assessment of drug efficacy against Plasmodium falciparum malaria: duration of follow-up.

Abstract

To determine the optimum duration of follow-up for the assessment of drug efficacy against Plasmodium falciparum malaria, 96 trial arms from randomized controlled trials (RCTs) with follow-up of 28 days or longer that were conducted between 1990 and 20

Stepniewska K Taylor WR Mayxay M Price R Smithuis F Guthmann JP Barnes K Myint HY Adjuik M Olliaro P Pukrittayakamee S Looareesuwan S Hien TT Farrar J Nosten F Day NP White NJ
Antimicrobial agents and chemotherapy 2004 Nov ; 48(11); 4271-80. doi: 10.1128/AAC.48.11.4271-4280.2004. Epub 2004 12 21