Pour rechercher une publication scientifique, insérez vos mots-clés en anglais.

Gametocyte carriage in uncomplicated Plasmodium falciparum malaria following treatment with artemisinin combination therapy: a systematic review and meta-analysis of individual patient data.


BACKGROUND: Gametocytes are responsible for transmission of malaria from human to mosquito. Artemisinin combination therapy (ACT) reduces post-treatment gametocyte carriage, dependent upon host, parasite and pharmacodynamic factors.

Référence de l'article: BMC medicine 2016 May 24; 14(); 79. doi: 10.1186/s12916-016-0621-7. Epub 2016 05 24
Drug resistance Gametocyte Malaria Plasmodium falciparum

Potential impact of multiple interventions on HIV incidence in a hyperendemic region in Western Kenya: a modelling study.


BACKGROUND: Multiple prevention interventions, including early antiretroviral therapy initiation, may reduce HIV incidence in hyperendemic settings.

Auteurs: Blaizot S Maman D Riche B Mukui I Kirubi B Ecochard R Etard JF
Référence de l'article: BMC infectious diseases 2016 Apr 29; 16(); 189. doi: 10.1186/s12879-016-1520-4. Epub 2016 04 29
Antiretroviral therapy HIV Hyperendemic settings Male circumcision Mathematical models Pre-exposure prophylaxis

Implementation and Operational Research: Feasibility of Using Tuberculin Skin Test Screening for Initiation of 36-Month Isoniazid Preventive Therapy in HIV-Infected Patients in Resource-Constrained Settings.


INTRODUCTION: The tuberculin skin test (TST) can be used to identify HIV-infected people who would benefit the most from long-term isoniazid preventive therapy (IPT).

Auteurs: Huerga H Mueller Y Ferlazzo G Mpala Q Bevilacqua P Vasquez B Noël Mekiedje C Ouattara A Mchunu G Weyenga HO Varaine F Bonnet M
Référence de l'article: Journal of acquired immune deficiency syndromes (1999) 2016 Apr 01; 71(4); e89-95. doi: 10.1097/QAI.0000000000000895. Epub 2016 07 06

The "Buruli Score": Development of a Multivariable Prediction Model for Diagnosis of Mycobacterium ulcerans Infection in Individuals with Ulcerative Skin Lesions, Akonolinga, Cameroon.


BACKGROUND: Access to laboratory diagnosis can be a challenge for individuals suspected of Buruli Ulcer (BU). Our objective was to develop a clinical score to assist clinicians working in resource-limited settings for BU diagnosis.

Auteurs: Mueller YK Bastard M Nkemenang P Comte E Ehounou G Eyangoh S Rusch B Tabah EN Trellu LT Etard JF
Référence de l'article: PLoS neglected tropical diseases 2016 Apr ; 10(4); e0004593. doi: 10.1371/journal.pntd.0004593. Epub 2016 04 05

A graphical method to assess distribution assumption in group-based trajectory models.


Group-based trajectory models had a rapid development in the analysis of longitudinal data in clinical research. In these models, the assumption of homoscedasticity of the residuals is frequently made but this assumption is not always met.

Auteurs: Elsensohn MH Klich A Ecochard R Bastard M Genolini C Etard JF Gustin MP
Référence de l'article: Statistical methods in medical research 2016 04 ; 25(2); 968-82. doi: 10.1177/0962280213475643. Epub 2013 02 19
Checking assumptions grouped-based trajectory models homoscedasticity longitudinal data model adequacy

Global phylogeography and evolutionary history of Shigella dysenteriae type 1.


Together with plague, smallpox and typhus, epidemics of dysentery have been a major scourge of human populations for centuries(1).

Auteurs: Njamkepo E Fawal N Tran-Dien A Hawkey J Strockbine N Jenkins C Talukder KA Bercion R Kuleshov K Kolínská R Russell JE Kaftyreva L Accou-Demartin M Karas A Vandenberg O Mather AE Mason CJ Page AJ Ramamurthy T Bizet C Gamian A Carle I Sow AG Bouchier C Wester AL Lejay-Collin M Fonkoua MC Le Hello S Blaser MJ Jernberg C Ruckly C Mérens A Page AL Aslett M Roggentin P Fruth A Denamur E Venkatesan M Bercovier H Bodhidatta L Chiou CS Clermont D Colonna B Egorova S Pazhani GP Ezernitchi AV Guigon G Harris SR Izumiya H Korzeniowska-Kowal A Lutyńska A Gouali M Grimont F Langendorf C Marejková M Peterson LA Perez-Perez G Ngandjio A Podkolzin A Souche E Makarova M Shipulin GA Ye C Žemličková H Herpay M Grimont PA Parkhill J Sansonetti P Holt KE Brisse S Thomson NR Weill FX
Référence de l'article: Nature microbiology 2016 03 21; 1(); 16027. doi: 10.1038/nmicrobiol.2016.27. Epub 2016 03 21

High-resolution spatial analysis of cholera patients reported in Artibonite department, Haiti in 2010-2011.


BACKGROUND: Cholera is caused by Vibrio cholerae, and is transmitted through fecal-oral contact. Infection occurs after the ingestion of the bacteria and is usually asymptomatic.

Auteurs: Allan M Grandesso F Pierre R Magloire R Coldiron M Martinez-Pino I Goffeau T Gitenet R François G Olson D Porten K Luquero FJ
Référence de l'article: Epidemics 2016 Mar ; 14(); 1-10. doi: 10.1016/j.epidem.2015.08.001. Epub 2015 09 03
Cholera Haiti Kulldorf Relative risk Spatial analysis

Light-emitting diode fluorescence microscopy for tuberculosis diagnosis: a meta-analysis.


Light-emitting diode fluorescence microscopy (LED-FM) is recommended by the World Health Organization to replace conventional Ziehl-Neelsen microscopy for pulmonary tuberculosis diagnosis. Uptake of LED-FM has been slow.

Auteurs: Chang EW Page AL Bonnet M
Référence de l'article: The European respiratory journal 2016 Mar ; 47(3); 929-37. doi: 10.1183/13993003.00978-2015. Epub 2015 12 02

Mortality Rates during Cholera Epidemic, Haiti, 2010-2011.


The 2010 cholera epidemic in Haiti was one of the largest cholera epidemics ever recorded.

Auteurs: Luquero FJ Rondy M Boncy J Munger A Mekaoui H Rymshaw E Page AL Toure B Degail MA Nicolas S Grandesso F Ginsbourger M Polonsky J Alberti KP Terzian M Olson D Porten K Ciglenecki I
Référence de l'article: Emerging infectious diseases 2016 Mar ; 22(3); 410-6. doi: 10.3201/eid2203.141970. Epub 2016 11 02
Haiti bacteria burden cholera epidemic mortality outbreak