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Epidemiology of HBV infection in a cohort of Ugandan HIV-infected patients and rate and pattern of lamivudine-resistant HBV infection in patients receiving antiretroviral therapy.


BACKGROUND: Many HIV-infected patients in sub-Saharan Africa are not routinely screened for hepatitis B virus (HBV) infection and are on antiretroviral therapy (ART) regimens containing only lamivudine as anti-HBV active drug.

Auteurs: Calisti G Muhindo R Boum Y Wilson LA Foster GM Geretti AM Bhagani S
Référence de l'article: Transactions of the Royal Society of Tropical Medicine and Hygiene 2015 Nov ; 109(11); 723-9. doi: 10.1093/trstmh/trv077. Epub 2015 09 18
Epidemiology HBV HIV Lamivudine Resistance Sub-Saharan Africa

Screening for psychological difficulties in young children in crisis: complementary cross-cultural validation.


BACKGROUND: Detection of children's psychological difficulties in crises and low resource settings is challenged by the lack of a validated, rapid and simple tool.

Auteurs: Marquer C Barry C Mouchenik Y Djibo DM Manzo ML Trujillo Maza EM Githaiga S Casas G Kirubi BW Marichez H Falissard B Moro MR Grais RF
Référence de l'article: International health 2015 Nov ; 7(6); 438-46. doi: 10.1093/inthealth/ihv006. Epub 2015 03 04
Children Cross cultural validation Humanitarian emergency Intervention Mental health Screening tool

Determinants of Visceral Leishmaniasis: A Case-Control Study in Gedaref State, Sudan.


BACKGROUND: Improving knowledge on local determinants of visceral leishmaniasis (VL) is crucial to guide the development of relevant control strategies.

Auteurs: Nackers F Mueller YK Salih N Elhag MS Elbadawi ME Hammam O Mumina A Atia AA Etard JF Ritmeijer K Chappuis F
Référence de l'article: PLoS neglected tropical diseases 2015 Nov ; 9(11); e0004187. doi: 10.1371/journal.pntd.0004187. Epub 2015 11 06

Preventive Effects of Long-Term Supplementation with 2 Nutritious Food Supplements in Young Children in Niger.


BACKGROUND: In nutritional crises, large-scale preventive distributions of specialized nutritious foods are recommended to prevent acute and chronic malnutrition in young children.

Auteurs: Sayyad-Neerkorn J Langendorf C Roederer T Doyon S Mamaty AA Woi-Messe L Manzo ML Harouna S de Pee S Grais RF
Référence de l'article: The Journal of nutrition 2015 Nov ; 145(11); 2596-603. doi: 10.3945/jn.115.213157. Epub 2015 09 30
Niger Super Cereal Plus acute malnutrition child malnutrition lipid-based nutrient supplements prevention stunting

Surgical Care of Pediatric Patients in the Humanitarian Setting: The Médecins Sans Frontières Experience, 2012-2013.


IMPORTANCE: Little is known about the scope of practice and outcomes in pediatric surgery performed by humanitarian organizations in resource-poor settings and conflict zones.

Auteurs: Trudeau MO Baron E Hérard P Labar AS Lassalle X Teicher CL Rothstein DH
Référence de l'article: JAMA surgery 2015 Nov ; 150(11); 1080-5. doi: 10.1001/jamasurg.2015.1928. Epub 2016 04 18

Comparison of weight-for-height and mid-upper arm circumference (MUAC) in a therapeutic feeding programme in South Sudan: is MUAC alone a sufficient criterion for admission of children at high risk of mortality?


OBJECTIVE: The present study was performed to describe the operational implications of using mid-upper arm circumference (MUAC) as a single admission criterion for treatment of severe acute malnutrition in South Sudan.

Auteurs: Grellety E Krause LK Shams Eldin M Porten K Isanaka S
Référence de l'article: Public health nutrition 2015 Oct ; 18(14); 2575-81. doi: 10.1017/S1368980015000737. Epub 2015 03 25
Admission criteria Child malnutrition Community-based management of acute malnutrition Mid-upper arm circumference Weight-for-height Z-score

Multidistrict Outbreak of Marburg Virus Disease-Uganda, 2012.


In October 2012, a cluster of illnesses and deaths was reported in Uganda and was confirmed to be an outbreak of Marburg virus disease (MVD).

Auteurs: Knust B Schafer IJ Wamala J Nyakarahuka L Okot C Shoemaker T Dodd K Gibbons A Balinandi S Tumusiime A Campbell S Newman E Lasry E DeClerck H Boum Y Makumbi I Bosa HK Mbonye A Aceng JR Nichol ST Ströher U Rollin PE
Référence de l'article: The Journal of infectious diseases 2015 Oct 01; 212 Suppl 2(); S119-28. doi: 10.1093/infdis/jiv351. Epub 2015 07 23
Marburg virus filoviruses hemorrhagic fever outbreak response zoonotic disease

Errors generated by a point-of-care CD4+ T-lymphocyte analyser: a retrospective observational study in nine countries.


OBJECTIVE: To estimate the proportion of invalid results generated by a CD4+ T-lymphocyte analyser used by Médecins Sans Frontières (MSF) in field projects and identify factors associated with invalid results.

Auteurs: Fajardo E Metcalf C Piriou E Gueguen M Maman D Chaillet P Cox V Rumaney MB Tunggal S Kosack C Roberts T
Référence de l'article: Bulletin of the World Health Organization 2015 Sep 01; 93(9); 623-30. doi: 10.2471/BLT.14.146480. Epub 2015 06 25

Inhaled Nitric Oxide as an Adjunctive Treatment for Cerebral Malaria in Children: A Phase II Randomized Open-Label Clinical Trial.


Background.  Children with cerebral malaria (CM) have high rates of mortality and neurologic sequelae. Nitric oxide (NO) metabolite levels in plasma and urine are reduced in CM. Methods.

Auteurs: Mwanga-Amumpaire J Carroll RW Baudin E Kemigisha E Nampijja D Mworozi K Santorino D Nyehangane D Nathan DI De Beaudrap P Etard JF Feelisch M Fernandez BO Berssenbrugge A Bangsberg D Bloch KD Boum Y Zapol WM
Référence de l'article: Open forum infectious diseases 2015 Sep ; 2(3); ofv111. doi: 10.1093/ofid/ofv111. Epub 2015 07 24
Plasmodium falciparum cerebral malaria methemoglobin nitric oxide

Routine use of Xpert® MTB/RIF in areas with different prevalences of HIV and drug-resistant tuberculosis.


SETTING: Despite the widespread introduction of Xpert(®) MTB/RIF in developing countries, reports of its use and value in routine conditions remain limited.

Auteurs: Page AL Ardizzoni E Lassovsky M Kirubi B Bichkova D Pedrotta A Lastrucci C de la Tour R Bonnet M Varaine F
Référence de l'article: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2015 Sep ; 19(9); 1078-83, i-iii. doi: 10.5588/ijtld.14.0951. Epub 2016 05 19