Publications

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Effects and cost of different strategies to eliminate hepatitis C virus transmission in Pakistan: a modelling analysis.

Abstract

BACKGROUND: The WHO elimination strategy for hepatitis C virus advocates scaling up screening and treatment to reduce global hepatitis C incidence by 80% by 2030, but little is known about how this reduction could be achieved and the c

Lim AG Walker JG Mafirakureva N Khalid GG Qureshi H Mahmood H Trickey A Fraser H Aslam K Falq G Fortas C Zahid H Naveed A Auat R Saeed Q Davies CF Mukandavire C Glass N Maman D Martin NK Hickman M May MT Hamid S Loarec A Averhoff F Vickerman P
The Lancet. Global health 2020 Mar ; 8(3); e440-e450. doi: 10.1016/S2214-109X(20)30003-6. Epub 2020 02 24

"We give them threatening advice…": expectations of adherence to antiretroviral therapy and their consequences among adolescents living with HIV in rural Malawi.

Abstract

INTRODUCTION: Many adolescents living with HIV in sub-Saharan Africa struggle to achieve optimal adherence to antiretroviral therapy (ART), but few studies have investigated how their treatment-taking decisions are influenced by their

Burns R Magalasi D Blasco P Szumilin E Pasquier E Schramm B Wringe A
Journal of the International AIDS Society 2020 Mar ; 23(3); e25459. doi: 10.1002/jia2.25459. Epub 2020 03 20
Malawi adherence adolescents living with HIV antiretroviral therapy qualitative

Increased risk of acquisition and transmission of ESBL-producing Enterobacteriaceae in malnourished children exposed to amoxicillin.

Abstract

OBJECTIVES: Routine amoxicillin for children with uncomplicated severe acute malnutrition raises concerns of increasing antibiotic resistance.

Maataoui N Langendorf C Berthe F Bayjanov JR van Schaik W Isanaka S Grais RF Clermont O Andremont A Armand-Lefèvre L Woerther PL
The Journal of antimicrobial chemotherapy 2020 03 01; 75(3); 709-717. doi: 10.1093/jac/dkz487. Epub 2020 12 22

The duration of chemoprophylaxis against malaria after treatment with artesunate-amodiaquine and artemether-lumefantrine and the effects of pfmdr1 86Y and pfcrt 76T: a meta-analysis of individual patient data.

Abstract

BACKGROUND: The majority of Plasmodium falciparum malaria cases in Africa are treated with the artemisinin combination therapies artemether-lumefantrine (AL) and artesunate-amodiaquine (AS-AQ), with amodiaquine being also widely used a

Bretscher MT Dahal P Griffin J Stepniewska K Bassat Q Baudin E D'Alessandro U Djimde AA Dorsey G Espié E Fofana B González R Juma E Karema C Lasry E Lell B Lima N Menéndez C Mombo-Ngoma G Moreira C Nikiema F Ouédraogo JB Staedke SG Tinto H Valea I Yeka A Ghani AC Guerin PJ Okell LC
BMC medicine 2020 Feb 25; 18(1); 47. doi: 10.1186/s12916-020-1494-3. Epub 2020 02 25
Amodiaquine Artemisinin Crt Drug Lumefantrine Malaria Mathematical model Trial mdr1

Prioritising pathogens for the management of severe febrile patients to improve clinical care in low- and middle-income countries.

Abstract

BACKGROUND: Severe febrile illness without a known source (SFWS) is a challenge for clinicians when deciding how to manage a patient, particularly given the wide spectrum of potential aetiologies that contribute to fever.

Osborn J Roberts T Guillen E Bernal O Roddy P Ongarello S Sprecher A Page AL Ribeiro I Piriou E Tamrat A de la Tour R Rao VB Flevaud L Jensen T McIver L Kelly C Dittrich S
BMC infectious diseases 2020 Feb 10; 20(1); 117. doi: 10.1186/s12879-020-4834-1. Epub 2020 02 10
Diagnostics Disease prioritization Fever causing pathogens Severe febrile illness

Evaluation of the stability of measles vaccine out of the cold chain under extended controlled temperature conditions.

Abstract

Measles outbreaks occur periodically in remote and difficult to reach areas in countries such as the Democratic Republic of Congo.

Juan-Giner A Alsalhani A Panunzi I Lambert V Van Herp M Gairola S
Vaccine 2020 Feb 08; doi: 10.1016/j.vaccine.2020.02.005. Epub 2020 02 08
Controlled temperature chain Extended controlled temperature conditions Measles Out of the cold chain Outbreak response

High cholera vaccination coverage following emergency campaign in Haiti: Results from a cluster survey in three rural Communes in the South Department, 2017.

Abstract

Oral cholera vaccine (OCV) has increasingly been used as an outbreak control measure, but vaccine shortages limit its application.

Sharp A Blake A Backx J Panunzi I Barrais R Nackers F Luquero F Deslouches YG Cohuet S
PLoS neglected tropical diseases 2020 Jan 31; 14(1); e0007967. doi: 10.1371/journal.pntd.0007967. Epub 2020 01 31

Effect of high-dose rifampicin on efavirenz pharmacokinetics: drug-drug interaction randomized trial.

Abstract

BACKGROUND: High-dose rifampicin is considered to shorten anti-TB treatment duration but its effect on antiretroviral metabolism is unknown.

Atwine D Baudin E Gelé T Muyindike W Mworozi K Kyohairwe R Kananura K Orikiriza P Nyehangane D K T Nanjebe D Furlan V Verstuyft C Barrail-Tran A Taburet AM Bonnet M
The Journal of antimicrobial chemotherapy 2020 Jan 30; doi: 10.1093/jac/dkz557. Epub 2020 01 30