Publications

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Efficacy of artesunate-amodiaquine for treating uncomplicated falciparum malaria in sub-Saharan Africa: a multi-centre analysis.

Abstract

BACKGROUND: Artesunate and amodiaquine (AS&AQ) is at present the world's second most widely used artemisinin-based combination therapy (ACT).

Zwang J Olliaro P Barennes H Bonnet M Brasseur P Bukirwa H Cohuet S D'Alessandro U Djimdé A Karema C Guthmann JP Hamour S Ndiaye JL Mårtensson A Rwagacondo C Sagara I Same-Ekobo A Sirima SB van den Broek I Yeka A Taylor WR Dorsey G Randrianarivelojosia M
Malaria journal 2009 Aug 23; 8 203. doi: 10.1186/1475-2875-8-203. Epub 2009 08 23

Varying efficacy of artesunate+amodiaquine and artesunate+sulphadoxine-pyrimethamine for the treatment of uncomplicated falciparum malaria in the Democratic Republic of Congo: a report of two in-vivo studies.

Abstract

BACKGROUND: Very few data on anti-malarial efficacy are available from the Democratic Republic of Congo (DRC). DRC changed its anti-malarial treatment policy to amodiaquine (AQ) and artesunate (AS) in 2005.

Bonnet M Broek Iv van Herp M Urrutia PP van Overmeir C Kyomuhendo J Ndosimao CN Ashley E Guthmann JP
Malaria journal 2009 Aug 10; 8 192. doi: 10.1186/1475-2875-8-192. Epub 2009 08 10

Prevalence study of yaws in the Democratic Republic of Congo using the lot quality assurance sampling method.

Abstract

BACKGROUND: Until the 1970s the prevalence of non-venereal trepanomatosis, including yaws, was greatly reduced after worldwide mass treatment. In 2005, cases were again reported in the Democratic Republic of the Congo.

Gerstl S Kiwila G Dhorda M Lonlas S Myatt M Ilunga BK Lemasson D Szumilin E Guerin PJ Ferradini L
PloS one 2009 Jul 22; 4(7); e6338. doi: 10.1371/journal.pone.0006338. Epub 2009 07 22

Nifurtimox-eflornithine combination therapy for second-stage African Trypanosoma brucei gambiense trypanosomiasis: a multicentre, randomised, phase III, non-inferiority trial.

Abstract

BACKGROUND: Human African trypanosomiasis (HAT; sleeping sickness) caused by Trypanosoma brucei gambiense is a fatal disease. Current treatment options for patients with second-stage disease are toxic, ineffective, or impractical.

Priotto G Kasparian S Mutombo W Ngouama D Ghorashian S Arnold U Ghabri S Baudin E Buard V Kazadi-Kyanza S Ilunga M Mutangala W Pohlig G Schmid C Karunakara U Torreele E Kande V
Lancet (London, England) 2009 Jul 04; 374(9683); 56-64. doi: 10.1016/S0140-6736(09)61117-X. Epub 2009 06 24

Characteristics of drug-resistant tuberculosis in Abkhazia (Georgia), a high-prevalence area in Eastern Europe.

Abstract

Although multidrug-resistant (MDR) tuberculosis (TB) is a major public health problem in Eastern Europe, the factors contributing to emergence, spread and containment of MDR-TB are not well defined.

Pardini M Niemann S Varaine F Iona E Meacci F Orrù G Yesilkaya H Jarosz T Andrew P Barer M Checchi F Rinder H Orefici G Rüsch-Gerdes S Fattorini L Oggioni MR Bonnet M
Tuberculosis (Edinburgh, Scotland) 2009 Jul ; 89(4); 317-24. doi: 10.1016/j.tube.2009.04.002. Epub 2009 06 17

Prevalence of Buruli ulcer in Akonolinga health district, Cameroon: results of a cross sectional survey.

Abstract

BACKGROUND: Buruli ulcer (BU) is a chronic, indolent necrotizing disease of the skin and underlying tissues caused by Mycobacterium ulcerans, which may result in functional incapacity.

Porten K Sailor K Comte E Njikap A Sobry A Sihom F Meva'a A Eyangoh S Myatt M Nackers F Grais RF
PLoS neglected tropical diseases 2009 Jun 23; 3(6); e466. doi: 10.1371/journal.pntd.0000466. Epub 2009 06 23

Risk factors for virological failure and subtherapeutic antiretroviral drug concentrations in HIV-positive adults treated in rural northwestern Uganda.

Abstract

BACKGROUND: Little is known about immunovirological treatment outcomes and adherence in HIV/AIDS patients on antiretroviral therapy (ART) treated using a simplified management approach in rural areas of developing countries, or about t

Ahoua L Guenther G Pinoges L Anguzu P Chaix ML Le Tiec C Balkan S Olson D Olaro C Pujades-Rodríguez M
BMC infectious diseases 2009 Jun 03; 9 81. doi: 10.1186/1471-2334-9-81. Epub 2009 06 03