Publications

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Treatment of severe malnutrition with 2-day intramuscular ceftriaxone vs 5-day amoxicillin.

Abstract

BACKGROUND: Systemic antibiotics are routinely prescribed for severe acute malnutrition (SAM). However, there is no consensus regarding the most suitable regimen.

Dubray C Ibrahim SA Abdelmutalib M Guerin PJ Dantoine F Belanger F Legros D Pinoges L Brown V
Annals of tropical paediatrics 2008 Mar ; 28(1); 13-22. doi: 10.1179/146532808X270635. Epub 2008 07 22

Population pharmacokinetics of piperaquine after two different treatment regimens with dihydroartemisinin-piperaquine in patients with Plasmodium falciparum malaria in Thailand.

Abstract

The population pharmacokinetics of piperaquine in adults and children with uncomplicated Plasmodium falciparum malaria treated with two different dosage regimens of dihydroartemisinin-piperaquine were characterized.

Tarning J Ashley EA Lindegardh N Stepniewska K Phaiphun L Day NP McGready R Ashton M Nosten F White NJ
Antimicrobial agents and chemotherapy 2008 Mar ; 52(3); 1052-61. doi: 10.1128/AAC.00955-07. Epub 2008 01 07

The dynamics of measles in sub-Saharan Africa.

Abstract

Although vaccination has almost eliminated measles in parts of the world, the disease remains a major killer in some high birth rate countries of the Sahel.

Ferrari MJ Grais RF Bharti N Conlan AJ Bjørnstad ON Wolfson LJ Guerin PJ Djibo A Grenfell BT
Nature 2008 Feb 07; 451(7179); 679-84. doi: 10.1038/nature06509. Epub 2008 03 12

Time is of the essence: exploring a measles outbreak response vaccination in Niamey, Niger.

Abstract

The current World Health Organization recommendations for response during measles epidemics focus on case management rather than outbreak response vaccination (ORV) campaigns, which may occur too late to impact morbidity and mortality and have a high c

Grais RF Conlan AJ Ferrari MJ Djibo A Le Menach A Bjørnstad ON Grenfell BT
Journal of the Royal Society, Interface 2008 Jan 06; 5(18); 67-74. doi: 10.1098/rsif.2007.1038. Epub 2008 03 04

Assessment of three new parasite lactate dehydrogenase (pan-pLDH) tests for diagnosis of uncomplicated malaria.

Abstract

A study to assess the diagnostic capabilities of three parasite lactate dehydrogenase (pan-pLDH) tests, Vistapan), Carestart and Parabank), was conducted in Uganda.

Fogg C Twesigye R Batwala V Piola P Nabasumba C Kiguli J Mutebi F Hook C Guillerm M Moody A Guthmann JP
Transactions of the Royal Society of Tropical Medicine and Hygiene 2008 Jan ; 102(1); 25-31. doi: 10.1016/j.trstmh.2007.09.014. Epub 2007 11 26

Risk associated with asymptomatic parasitaemia occurring post-antimalarial treatment.

Abstract

OBJECTIVE: Parasites may recur asymptomatically after initial clearance by antimalarial treatment. Current guidelines recommend treatment only when patients develop symptoms or at the end of follow-up.

Olliaro P Pinoges L Checchi F Vaillant M Guthmann JP
Tropical medicine & international health : TM & IH 2008 Jan ; 13(1); 83-90. doi: 10.1111/j.1365-3156.2007.01977.x. Epub 2008 03 11

Nifurtimox-eflornithine combination therapy for second-stage Trypanosoma brucei gambiense sleeping sickness: a randomized clinical trial in Congo.

Abstract

BACKGROUND: Human African trypanosomiasis caused by Trypanosoma brucei gambiense is a fatal disease. Current treatment options for patients with second-stage disease are either highly toxic or impracticable in field conditions.

Priotto G Kasparian S Ngouama D Ghorashian S Arnold U Ghabri S Karunakara U
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2007 Dec 01; 45(11); 1435-42. doi: 10.1086/522982. Epub 2007 10 22

Positive outcomes of HAART at 24 months in HIV-infected patients in Cambodia.

Abstract

OBJECTIVES: African and Asian cohort studies have demonstrated the feasibility and efficacy of HAART in resource-poor settings.

Ferradini L Laureillard D Prak N Ngeth C Fernandez M Pinoges L Puertas G Taburet AM Ly N Rouzioux C Balkan S Quillet C Delfraissy JF
AIDS (London, England) 2007 Nov 12; 21(17); 2293-301. doi: 10.1097/QAD.0b013e32828cc8b7. Epub 2008 03 10

World Antimalarial Resistance Network I: clinical efficacy of antimalarial drugs.

Abstract

The proliferation of antimalarial drug trials in the last ten years provides the opportunity to launch a concerted global surveillance effort to monitor antimalarial drug efficacy.

Price RN Dorsey G Ashley EA Barnes KI Baird JK d'Alessandro U Guerin PJ Laufer MK Naidoo I Nosten F Olliaro P Plowe CV Ringwald P Sibley CH Stepniewska K White NJ
Malaria journal 2007 Sep 06; 6 119. doi: 10.1186/1475-2875-6-119. Epub 2007 09 06