Publications

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Community-based COVID-19 active case finding and rapid response in the Democratic Republic of the Congo: Improving case detection and response.

Abstract

A community-based coronavirus disease (COVID-19) active case-finding strategy using an antigen-detecting rapid diagnostic test (Ag-RDT) was implemented in the Democratic Republic of Congo (DRC) to enhance COVID-19 case detection.

Otshudiema JO Folefack GLT Nsio JM Kakema CH Minikulu L Bafuana A Kosianza JB Mfumu AK Nkwembe E Munyeku-Bazitama Y Makiala-Mandanda S Guinko N Mbuyi G Tshilumbu JK Saidi GN Umba-di-Masiala MS Ebondo AK Mutonj JJ Kalombo S Kabeya J Mawanda TK Bile FN Kasereka GK Mbala-Kingebeni P Ahuka-Mundeke S Karamagi HC Fai KN Djiguimde AP
PloS one 2023 ; 18(5); . doi: 10.1371/journal.pone.0278251. Epub 2023 05 18

Immunogenicity and safety of fractional doses of 17D-213 yellow fever vaccine in children (YEFE): a randomised, double-blind, non-inferiority substudy of a phase 4 trial.

Abstract

BACKGROUND: Current supply shortages constrain yellow fever vaccination activities, particularly outbreak response.

Juan-Giner A Namulwana ML Kimathi D Grantz KH Fall G Dia M Bob NS Sall AA Nerima C Sahani MK Mulogo EM Ampeire I Hombach J Nanjebe D Mwanga-Amumpaire J Cummings DAT Bejon P Warimwe GM Grais RF
The Lancet. Infectious diseases 2023 Apr 28; . doi: 10.1016/S1473-3099(23)00131-7. Epub 2023 04 28

Immunogenicity and safety of fractional doses of 17D-213 yellow fever vaccine in HIV-infected people in Kenya (YEFE): a randomised, double-blind, non-inferiority substudy of a phase 4 trial.

Abstract

BACKGROUND: Evidence indicates that fractional doses of yellow fever vaccine are safe and sufficiently immunogenic for use during yellow fever outbreaks.

Kimathi D Juan-Giner A Orindi B Grantz KH Bob NS Cheruiyot S Hamaluba M Kamau N Fall G Dia M Mosobo M Moki F Kiogora K Chirro O Thiong'o A Mwendwa J Guantai A Karanja HK Gitonga J Mugo D Ramko K Faye O Sanders EJ Grais RF Bejon P Warimwe GM
The Lancet. Infectious diseases 2023 Apr 28; . doi: 10.1016/S1473-3099(23)00114-7. Epub 2023 04 28

Comparative effectiveness of adding delamanid to a multidrug-resistant tuberculosis regimen comprised of three drugs likely to be effective.

Abstract

Clarity about the role of delamanid in longer regimens for multidrug-resistant TB is needed after discordant Phase IIb and Phase III randomized controlled trial results.

Rodriguez CA Lodi S Horsburgh CR Mitnick CD Bastard M Huerga H Khan U Rich M Seung KJ Atwood S Manzur-Ul-Alam M Melikyan N Mpinda S Myint Z Naidoo Y Petrosyan O Salahuddin N Sarfaraz S Vilbrun SC Yae K Achar J Ahmed S Algozhina E Beauchamp J de Guadelupe Perea Moreno S Gulanbaeva M Gergedava M Indah Sari CY Hewison C Khan P Franke MF
PLOS global public health 2023 ; 3(4); . doi: 10.1371/journal.pgph.0000818. Epub 2023 04 28
Campbell JR Chan ED Anderson LF Bonnet M Brode SK Cegielski JP Guglielmetti L Singla R Fox GJ Skrahina A Rodrigues D Kuksa L Viiklepp P Menzies D
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2023 Apr 01; 27(4); . doi: 10.5588/ijtld.22.0678. Epub 2023 04 10

Mortality and Cause of Death in Children With Presumptive Disseminated Tuberculosis.

Abstract

BACKGROUND AND OBJECTIVES: Children experience high tuberculosis (TB)-related mortality but causes of death among those with presumptive TB are poorly documented.

Bonnet M Nordholm AC Ssekyanzi B Byamukama O Orikiriza P Tusabe T Nyehangane D Taremwa IM Turyashemererwa E Wobudeya E Mwanga-Amumpaire J Marais BJ Nampijja D
Pediatrics 2023 Apr 01; 151(4); . doi: 10.1542/peds.2022-057912. Epub 2023 04 04

A prospective, multi-site, cohort study to estimate incidence of infection and disease due to Lassa fever virus in West African countries (the Enable Lassa research programme)-Study protocol.

Abstract

BACKGROUND: Lassa fever (LF), a haemorrhagic illness caused by the Lassa fever virus (LASV), is endemic in West Africa and causes 5000 fatalities every year.

Penfold S Adegnika AA Asogun D Ayodeji O Azuogu BN Fischer WA Garry RF Grant DS Happi C N'Faly M Olayinka A Samuels R Sibley J Wohl DA Accrombessi M Adetifa I Annibaldis G Camacho A Dan-Nwafor C Deha ARE DeMarco J Duraffour S Goba A Grais R Günther S Honvou ÉJJP Ihekweazu C Jacobsen C Kanneh L Momoh M Ndiaye A Nsaibirni R Okogbenin S Ochu C Ogbaini E Logbo ÉPMA Sandi JD Schieffelin JS Verstraeten T Vielle NJ Yadouleton A Yovo EK
PloS one 2023 ; 18(3); . doi: 10.1371/journal.pone.0283643. Epub 2023 03 30