Publications

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Safety and effectiveness outcomes from a 14-country cohort of patients with multi-drug resistant tuberculosis treated concomitantly with bedaquiline, delamanid and other second-line drugs.

Abstract

BACKGROUND: Concomitant use of bedaquiline (Bdq) and delamanid (Dlm) for multi-drug/rifampicin resistant tuberculosis (MDR/RR-TB) has raised concerns about a potentially poor risk-benefit ratio.

Huerga H Khan U Bastard M Mitnick CD Lachenal N Khan PY Seung KJ Melikyan N Ahmed S Rich ML Varaine F Osso E Rashitov M Salahuddin N Salia G Sánchez E Serobyan A Siddiqui MR Tefera DG Vetushko D Yeghiazaryan L Holtzman D Islam S Kumsa A Leblanc GJ Leonovich O Mamsa S Manzur-Ul-Alam M Myint Z Padayachee S Franke MF Hewison C
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2022 Mar 04; doi: 10.1093/cid/ciac176. Epub 2022 03 04
adverse events combination therapy endTB linezolid

Growth and CD4 patterns of adolescents living with perinatally acquired HIV worldwide, a CIPHER cohort collaboration analysis.

Abstract

INTRODUCTION: Adolescents living with HIV are subject to multiple co-morbidities, including growth retardation and immunodeficiency.

Jesson J Crichton S Quartagno M Yotebieng M Abrams EJ Chokephaibulkit K Le Coeur S Aké-Assi MH Patel K Pinto J Paul M Vreeman R Davies MA Ben-Farhat J Van Dyke R Judd A Mofenson L Vicari M Seage G Bekker LG Essajee S Gibb D Penazzato M Collins IJ Wools-Kaloustian K Slogrove A Powis K Williams P Matshaba M Thahane L Nyasulu P Lukhele B Mwita L Kekitiinwa-Rukyalekere A Wanless S Goetghebuer T Thorne C Warszawski J Galli L van Rossum AMC Giaquinto C Marczynska M Marques L Prata F Ene L Okhonskaya L Navarro M Frick A Naver L Kahlert C Volokha A Chappell E Pape JW Rouzier V Marcelin A Succi R Sohn AH Kariminia A Edmonds A Lelo P Lyamuya R Ogalo EA Odhiambo FA Haas AD Bolton C Muhairwe J Tweya H Sylla M D'Almeida M Renner L Abzug MJ Oleske J Purswani M Teasdale C Nuwagaba-Biribonwoha H Goodall R Leroy V
Journal of the International AIDS Society 2022 Mar ; 25(3); e25871. doi: 10.1002/jia2.25871. Epub 2022 03 07
CD4 HIV adolescent cohort studies growth perinatally acquired

Effectiveness of a monthly schedule of follow-up for the treatment of uncomplicated severe acute malnutrition in Sokoto, Nigeria: A cluster randomized crossover trial.

Abstract

BACKGROUND: Community-based management of severe acute malnutrition (SAM) involves weekly or biweekly outpatient clinic visits for clinical surveillance and distribution of therapeutic foods.

Hitchings MDT Berthé F Aruna P Shehu I Hamza MA Nanama S Steve-Edemba C Grais RF Isanaka S
PLoS medicine 2022 Mar ; 19(3); e1003923. doi: 10.1371/journal.pmed.1003923. Epub 2022 03 01

Snakebite epidemiology in humans and domestic animals across the Terai region in Nepal: a multicluster random survey.

Abstract

BACKGROUND: Each year, 2 million people worldwide are bitten by snakes, resulting in an estimated 81 000-138 000 deaths.

Alcoba G Sharma SK Bolon I Ochoa C Babo Martins S Subedi M Shah B Ghimire A Gignoux E Luquero F Ruiz de Castañeda R Ray N Chappuis F
The Lancet. Global health 2022 Mar ; 10(3); e398-e408. doi: 10.1016/S2214-109X(22)00028-6. Epub 2022 02 21

Knowledge, attitudes and practices on childhood TB among healthcare workers.

Abstract

Increasing childhood TB case detection requires the deployment of diagnostic services at peripheral healthcare level. Capacity and readiness of healthcare workers (HCWs) are key to the delivery of innovative approaches.

Joshi B Font H Wobudeya E Nanfuka M Kobusingye A Mwanga-Amumpaire J Natukunda N Turyahabwe S Borand L Mao TE Dim B Ferhi R Moh R Kouakou J Aka Bony R Breton G Mustapha A Matata L Foray L Detjen A Verkuijl S Sekadde M Khosa C Mbassa V Taguebue JV Kwedi Nolna S Bonnet M Marcy O Orne-Gliemann J
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2022 Mar 01; 26(3); 243-251. doi: 10.5588/ijtld.21.0317. Epub 2022 02 24

Permethrin-treated baby wraps for the prevention of malaria: results of a randomized controlled pilot study in rural Uganda.

Abstract

BACKGROUND: Progress against malaria has stalled and may even be slipping backwards in high-burden countries.

Boyce RM Muhindo E Baguma E Muhindo R Shem B François R Hawke S Shook-Sa BE Ntaro M Nalusaji A Nyehangane D Reyes R Juliano JJ Siedner MJ Staedke SG Mulogo EM
Malaria journal 2022 Feb 23; 21(1); 63. doi: 10.1186/s12936-022-04086-w. Epub 2022 02 23
Insecticide-treated clothing Malaria Permethrin Plasmodium Prevention

Inference is bliss: Simulation for power estimation for an observational study of a cholera outbreak intervention.

Abstract

BACKGROUND: The evaluation of ring vaccination and other outbreak-containment interventions during severe and rapidly-evolving epidemics presents a challenge for the choice of a feasible study design, and subsequently, for the estimati

Ratnayake R Checchi F Jarvis CI Edmunds WJ Finger F
PLoS neglected tropical diseases 2022 Feb 16; 16(2); e0010163. doi: 10.1371/journal.pntd.0010163. Epub 2022 02 16

Shifting to Tele-Mental Health in humanitarian and crisis settings: an evaluation of Médecins Sans Frontières experience during the COVID-19 pandemic.

Abstract

BACKGROUND: 'Tele-Mental Health (MH) services,' are an increasingly important way to expand care to underserved groups in low-resource settings.

Ibragimov K Palma M Keane G Ousley J Crowe M Carreño C Casas G Mills C Llosa A
Conflict and health 2022 Feb 14; 16(1); 6. doi: 10.1186/s13031-022-00437-1. Epub 2022 02 14
MHPSS Remote mental health Tele-counselling Tele-mental health Telepsychiatry

Cervical cancer screening coverage and its related knowledge in southern Malawi.

Abstract

BACKGROUND: Cervical cancer (CC) is the fourth most common cancer among women worldwide and Malawi has the world's highest rate of cervical cancer related mortality.

Gerstl S Lee L Nesbitt RC Mambula C Sugianto H Phiri T Kachingwe J Llosa AE
BMC public health 2022 Feb 14; 22(1); 295. doi: 10.1186/s12889-022-12547-9. Epub 2022 02 14
Barriers Cervical cancer Cervical cancer screening Coverage survey Cross sectional study Health behaviours Knowledge and attitude Malawi Precancerous lesions Reproductive health