Publications

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Efficacy of chloroquine, sulfadoxine-pyrimethamine and amodiaquine for treatment of uncomplicated Plasmodium falciparum malaria among children under five in Bongor and Koumra, Chad.

Abstract

We report two 28-day in-vivo antimalarial efficacy studies carried out in the urban centres of Bongor and Koumra, southern Chad.

Grandesso F Bachy C Donam I Ntambi J Habimana J D'Alessandro U Maikere J Vanlerberghe V Kerah CH Guthmann JP
Transactions of the Royal Society of Tropical Medicine and Hygiene 2006 May ; 100(5); 419-26. doi: 10.1016/j.trstmh.2005.07.017. Epub 2005 11 16

Scaling up of highly active antiretroviral therapy in a rural district of Malawi: an effectiveness assessment.

Abstract

BACKGROUND: The recording of outcomes from large-scale, simplified HAART (highly active antiretroviral therapy) programmes in sub-Saharan Africa is critical.

Ferradini L Jeannin A Pinoges L Izopet J Odhiambo D Mankhambo L Karungi G Szumilin E Balandine S Fedida G Carrieri MP Spire B Ford N Tassie JM Guerin PJ Brasher C
Lancet (London, England) 2006 Apr 22; 367(9519); 1335-42. doi: 10.1016/S0140-6736(06)68580-2. Epub 2006 05 04

Operational response to malaria epidemics: are rapid diagnostic tests cost-effective?

Abstract

OBJECTIVE: To compare the cost-effectiveness of malaria treatment based on presumptive diagnosis with that of malaria treatment based on rapid diagnostic tests (RDTs).

Rolland E Checchi F Pinoges L Balkan S Guthmann JP Guerin PJ
Tropical medicine & international health : TM & IH 2006 Apr ; 11(4); 398-408. doi: 10.1111/j.1365-3156.2006.01580.x. Epub 2006 05 09

A comparison of cluster and systematic sampling methods for measuring crude mortality.

Abstract

OBJECTIVE: To compare the results of two different survey sampling techniques (cluster and systematic) used to measure retrospective mortality on the same population at about the same time.

Rose AM Grais RF Coulombier D Ritter H
Bulletin of the World Health Organization 2006 Apr ; 84(4); 290-6. doi: /S0042-96862006000400013. Epub 2006 04 13

Geographical distribution of selected and putatively neutral SNPs in Southeast Asian malaria parasites.

Abstract

Loci targeted by directional selection are expected to show elevated geographical population structure relative to neutral loci, and a flurry of recent papers have used this rationale to search for genome regions involved in adaptation.

Anderson TJ Nair S Sudimack D Williams JT Mayxay M Newton PN Guthmann JP Smithuis FM Tran TH van den Broek IV White NJ Nosten F
Molecular biology and evolution 2005 Dec ; 22(12); 2362-74. doi: 10.1093/molbev/msi235. Epub 2005 08 10

Diagnostic accuracy of two rK39 antigen-based dipsticks and the formol gel test for rapid diagnosis of visceral leishmaniasis in northeastern Uganda.

Abstract

The development of an accurate, practical, and affordable diagnostic test is essential to improve the management of visceral leishmaniasis (VL) in remote health centers.

Chappuis F Mueller Y Nguimfack A Rwakimari JB Couffignal S Boelaert M Cavailler P Loutan L Piola P
Journal of clinical microbiology 2005 Dec ; 43(12); 5973-7. doi: 10.1128/JCM.43.12.5973-5977.2005. Epub 2006 01 19

Genetic heterogeneity of hepatitis E virus in Darfur, Sudan, and neighboring Chad.

Abstract

The within-outbreak diversity of hepatitis E virus (HEV) was studied during the outbreak of hepatitis E that occurred in Sudan in 2004.

Nicand E Armstrong GL Enouf V Guthmann JP Guerin JP Caron M Nizou JY Andraghetti R
Journal of medical virology 2005 Dec ; 77(4); 519-21. doi: 10.1002/jmv.20487. Epub 2006 01 17