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A cluster randomized non-inferiority field trial on the immunogenicity and safety of tetanus toxoid vaccine kept in controlled temperature chain compared to cold chain.

Abstract

BACKGROUND: In resource-poor settings, cold chain requirements present barriers for vaccine delivery.

Juan-Giner A Domicent C Langendorf C Roper MH Baoundoh P Fermon F Gakima P Zipursky S Tamadji M Grais RF
Vaccine 2014 Oct 29; 32(47); 6220-6. doi: 10.1016/j.vaccine.2014.09.027. Epub 2014 09 26
Cold chain Controlled temperature chain Immunogenicity Maternal and neonatal tetanus elimination NCT01559597 Tetanus toxoid

Physiotherapy for poliomyelitis: a descriptive study in the Republic of Congo.

Abstract

BACKGROUND: A large poliomyelitis outbreak occurred in 2010 in the Republic of Congo. This paper describes the demographic and clinical characteristics of poliomyelitis cases and their outcomes following physiotherapy.

Mancini S Coldiron ME Nicholas S Llosa AE Mouniaman-Nara I Ngala J Grais RF Porten K
BMC research notes 2014 Oct 23; 7 755. doi: 10.1186/1756-0500-7-755. Epub 2014 10 23

Emergence of Zaire Ebola virus disease in Guinea.

Abstract

In March 2014, the World Health Organization was notified of an outbreak of a communicable disease characterized by fever, severe diarrhea, vomiting, and a high fatality rate in Guinea.

Baize S Pannetier D Oestereich L Rieger T Koivogui L Magassouba N Soropogui B Sow MS Keïta S De Clerck H Tiffany A Dominguez G Loua M Traoré A Kolié M Malano ER Heleze E Bocquin A Mély S Raoul H Caro V Cadar D Gabriel M Pahlmann M Tappe D Schmidt-Chanasit J Impouma B Diallo AK Formenty P Van Herp M Günther S
The New England journal of medicine 2014 Oct 09; 371(15); 1418-25. doi: 10.1056/NEJMoa1404505. Epub 2014 04 16

Evaluation of the modified colorimetric resazurin microtiter plate-based antibacterial assay for rapid and reliable tuberculosis drug susceptibility testing.

Abstract

BACKGROUND: The resazurin microtiter assay (classic REMA), a colorimetric liquid culture-based drug susceptibility assay for Mycobacterium tuberculosis (MTB), has been endorsed by the World Health Organization.

Katawera V Siedner M Boum Y
BMC microbiology 2014 Oct 07; 14 259. doi: 10.1186/s12866-014-0259-6. Epub 2014 10 07

Plasmodium prevalence and artemisinin-resistant falciparum malaria in Preah Vihear Province, Cambodia: a cross-sectional population-based study.

Abstract

BACKGROUND: Intensified efforts are urgently needed to contain and eliminate artemisinin-resistant Plasmodium falciparum in the Greater Mekong subregion.

Bosman P Stassijns J Nackers F Canier L Kim N Khim S Alipon SC Chuor Char M Chea N Dysoley L Van den Bergh R Etienne W De Smet M Ménard D Kindermans JM
Malaria journal 2014 Oct 06; 13 394. doi: 10.1186/1475-2875-13-394. Epub 2014 10 06

[Long term adherence to HAART in Senegal].

Abstract

Adherence is one of the main predictors of antiretroviral treatment success. A governmental initiative was launched in 1998 for HIV-infected patients in Senegal to provide access to highly active antiretroviral therapy (HAART).

Bastard M Fall MB
Bulletin de la Societe de pathologie exotique (1990) 2014 Oct ; 107(4); 241-3. doi: 10.1007/s13149-014-0346-9. Epub 2014 03 10

Outcomes of antiretroviral therapy over a 10-year period of expansion: a multicohort analysis of African and Asian HIV programs.

Abstract

OBJECTIVE: Little is known about the evolution of program outcomes associated with rapid expansion of antiretroviral therapy (ART) in resource-limited settings.

Grimsrud A Balkan S Casas EC Lujan J Van Cutsem G Poulet E Myer L Pujades-Rodriguez M
Journal of acquired immune deficiency syndromes (1999) 2014 Oct 01; 67(2); e55-66. doi: 10.1097/QAI.0000000000000268. Epub 2015 01 06

Vaccination in humanitarian crises: satisficing should no longer suffice.

Abstract

There are more possible vaccination interventions to mitigate the adverse health consequences of populations in crises than ever before, but recent reviews suggest delivering these vaccines has been fraught with difficulty.

Grais RF Juan-Giner A
International health 2014 Sep ; 6(3); 160-1. doi: 10.1093/inthealth/ihu051. Epub 2014 08 04
Crises Humanitarian Vaccination Vaccines

Preventing acute malnutrition among young children in crises: a prospective intervention study in Niger.

Abstract

BACKGROUND: Finding the most appropriate strategy for the prevention of moderate acute malnutrition (MAM) and severe acute malnutrition (SAM) in young children is essential in countries like Niger with annual "hunger gaps." Options for

Langendorf C Roederer T de Pee S Brown D Doyon S Mamaty AA Touré LW Manzo ML Grais RF
PLoS medicine 2014 Sep ; 11(9); e1001714. doi: 10.1371/journal.pmed.1001714. Epub 2014 09 02