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Treatment outcomes of patients switching from an injectable drug to bedaquiline during short standardized MDR-TB treatment in Mozambique.


Bedaquiline was recommended by WHO as the preferred option in treatment of MDR-TB patients with long regimen. However, no recommendation was given for the short MDR-TB regimen.

Auteurs: Bastard M Molfino L Mutaquiha C Galindo MA Zindoga P Vaz D Mahinça I du Cros P Rusch B Telnov A
Référence de l'article: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2019 Mar 11; (); Array. doi: 10.1093/cid/ciz196. Epub 2019 03 11

Control of Ebola virus disease outbreaks: Comparison of health care worker-targeted and community vaccination strategies.


BACKGROUND: Health care workers (HCW) are at risk of infection during Ebola virus disease outbreaks and therefore may be targeted for vaccination before or during outbreaks.

Auteurs: Robert A Camacho A Edmunds WJ Baguelin M Muyembe Tamfum JJ Rosello A Kéïta S Eggo RM
Référence de l'article: Epidemics 2019 Mar 02; (); Array. doi: 10.1016/j.epidem.2019.03.001. Epub 2019 03 02
Ebola Health care workers Outbreak control Public health Vaccination

Deriving the optimal limit of detection for an HCV point-of-care test for viraemic infection: Analysis of a global dataset.


BACKGROUND & AIMS: Affordable point-of-care tests for hepatitis C (HCV) viraemia are needed to improve access to treatment in low- and middle-income countries.

Auteurs: Freiman JM Wang J Easterbrook PJ Horsburgh CR Marinucci F White LF Kamkamidze G Krajden M Loarec A Njouom R Nguyen KV Shiha G Soliman R Solomon SS Tsertsvadze T Denkinger CM Linas B
Référence de l'article: Journal of hepatology 2019 Feb 21; (); Array. doi: 10.1016/j.jhep.2019.02.011. Epub 2019 02 21
Diagnosis Hepatitis C virus Limit of detection Point-of-care Viraemia, Affordable

Estimating cholera incidence with cross-sectional serology.


The development of new approaches to cholera control relies on an accurate understanding of cholera epidemiology.

Auteurs: Azman AS Lessler J Luquero FJ Bhuiyan TR Khan AI Chowdhury F Kabir A Gurwith M Weil AA Harris JB Calderwood SB Ryan ET Qadri F Leung DT
Référence de l'article: Science translational medicine 2019 Feb 20; 11(480); Array. doi: 10.1126/scitranslmed.aau6242. Epub 2019 03 29

Mortality in the first six months among HIV-positive and HIV-negative patients empirically treated for tuberculosis.


BACKGROUND: Empirical treatment of tuberculosis (TB) may be necessary in patients with negative or no Xpert MTB/RIF results.

Auteurs: Huerga H Ferlazzo G Wanjala S Bastard M Bevilacqua P Ardizzoni E Sitienei J Bonnet M
Référence de l'article: BMC infectious diseases 2019 Feb 11; 19(1); 132. doi: 10.1186/s12879-019-3775-z. Epub 2019 02 11
Diagnosis Empirical treatment HIV Mortality Resource-constrained Tuberculosis

Demonstration of the diagnostic agreement of capillary and venous blood samples, using hepatitis-C virus SD Bioline rapid test: A clinic-based study.


BACKGROUND: Simplifying hepatitis C virus (HCV) screening is a key step in achieving the elimination of HCV as a global public health threat by 2030.

Auteurs: Sun C Iwamoto M Calzia A Sreng B Yann S Pin S Lastrucci C Kimchamroeun S Dimanche C Dousset JP Le Paih M Balkan S Marquardt T Carnimeo V Lissouba P Maman D Loarec A
Référence de l'article: Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2019 Feb ; 111(); 39-41. doi: 10.1016/j.jcv.2018.12.008. Epub 2018 12 31
Blood specimen collection HCV screening Hepatitis C virus SD Bioline(©) Sample equivalence

Extremely low hepatitis C prevalence among HIV co-infected individuals in four countries in sub-Saharan Africa.


: A multicentric, retrospective case-series analysis (facility-based) in five sites across Kenya, Malawi, Mozambique, and Uganda screened HIV-positive adults for hepatitis C virus (HCV) antibodies using Oraquick rapid testing and viral confirmation (in

Auteurs: Loarec A Carnimeo V Molfino L Kizito W Muyindike W Andrieux-Meyer I Balkan S Nzomukunda Y Mwanga-Amumpaire J Ousley J Bygrave H Maman D
Référence de l'article: AIDS (London, England) 2019 Feb 01; 33(2); 353-355. doi: 10.1097/QAD.0000000000002070. Epub 2019 01 20