Publications

Pour rechercher une publication scientifique, insérez vos mots-clés en anglais.
ENG

Depression and Suicidal Ideation Among HIV-Infected Adults Receiving Efavirenz Versus Nevirapine in Uganda: A Prospective Cohort Study.

Abstract

Background: Evidence regarding potential adverse neuropsychiatric effects of efavirenz is conflicting, and data from sub-Saharan Africa, where 70% of persons living with HIV (PLHIV) reside and efavirenz is used as first-line therapy, a

Auteurs: Chang JL Tsai AC Musinguzi N Haberer JE Boum Y Muzoora C Bwana M Martin JN Hunt PW Bangsberg DR Siedner MJ
Référence de l'article: Annals of internal medicine 2018 Aug 07; 169(3); 146-155. doi: 10.7326/M17-2252. Epub 2018 06 26
ENG

Xpert MTB/RIF diagnosis of childhood tuberculosis from sputum and stool samples in a high TB-HIV-prevalent setting.

Abstract

The Xpert MTB/RIF assay is a major advance for diagnosis of tuberculosis (TB) in high-burden countries but is limited in children by their difficulty to produce sputum.

Auteurs: Orikiriza P Nansumba M Nyehangane D Bastard M Mugisha IT Nansera D Mwanga-Amumpaire J Boum Y Kumbakumba E Bonnet M
Référence de l'article: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 2018 Aug ; 37(8); 1465-1473. doi: 10.1007/s10096-018-3272-0. Epub 2018 05 08
Childhood tuberculosis Sputum Stool Xpert MTB/RIF
ENG

Evaluation of the SD bioline cholera rapid diagnostic test during the 2016 cholera outbreak in Lusaka, Zambia.

Abstract

OBJECTIVE: To assess the performance of the SD Bioline Cholera Ag O1/O139 rapid diagnostic test (RDT) compared to a reference standard combining culture and PCR for the diagnosis of cholera cases during an outbreak.

Auteurs: Mwaba J Ferreras E Chizema-Kawesa E Mwimbe D Tafirenyika F Rauzier J Blake A Rakesh A Poncin M Stoitsova S Kwenda G Azman AS Chewe O Serafini M Lukwesa-Musyani C Cohuet S Quilici ML Luquero FJ Page AL
Référence de l'article: Tropical medicine & international health : TM & IH 2018 Aug ; 23(8); 834-840. doi: 10.1111/tmi.13084. Epub 2018 06 29
cholera choléra diagnostic accuracy outbreak précision diagnostique rapid diagnostic test test de diagnostic rapide épidémie
ENG

Distribution and Performance of Cardiovascular Risk Scores in a Mixed Population of HIV-Infected and Community-Based HIV-Uninfected Individuals in Uganda.

Abstract

BACKGROUND: The utility and validity of cardiovascular diseases (CVD) risk scores are not well studied in sub-Saharan Africa.

Auteurs: Muiru AN Bibangambah P Hemphill L Sentongo R Kim JH Triant VA Bangsberg DR Tsai AC Martin JN Haberer JE Boum Y Plutzky J Hunt PW Okello S Siedner MJ
Référence de l'article: Journal of acquired immune deficiency syndromes (1999) 2018 Aug 01; 78(4); 458-464. doi: 10.1097/QAI.0000000000001696. Epub 2018 11 14
ENG

Pharmacokinetics of efavirenz in patients on antituberculosis treatment in high human immunodeficiency virus and tuberculosis burden countries: A systematic review.

Abstract

AIMS: Efavirenz (EFV) and rifampicin-isoniazid (RH) are cornerstone drugs in human immunodeficiency virus (HIV)-tuberculosis (TB) coinfection treatment but with complex drug interactions, efficacy and safety challenges.

Auteurs: Atwine D Bonnet M Taburet AM
Référence de l'article: British journal of clinical pharmacology 2018 Aug ; 84(8); 1641-1658. doi: 10.1111/bcp.13600. Epub 2018 05 22
HIV/AIDS < infectious diseases adverse drug reactions antiretrovirals < infectious diseases genetics and pharmacogenetics pharmacokinetics
ENG

HIV Infection and risk of postpartum infection, complications and mortality in rural Uganda.

Abstract

HIV infection may increase risk of postpartum infection and infection-related mortality. We hypothesized that postpartum infection incidence and attributable mortality in Mbarara, Uganda would be higher in HIV-infected than HIV-uninfected women.

Auteurs: Bebell LM Ngonzi J Siedner MJ Muyindike WR Bwana BM Riley LE Boum Y Bangsberg DR Bassett IV
Référence de l'article: AIDS care 2018 Aug ; 30(8); 943-953. doi: 10.1080/09540121.2018.1434119. Epub 2018 02 16
Africa HIV antiretroviral infection pregnancy puerperal sepsis
ENG

Estimating program coverage in the treatment of severe acute malnutrition: a comparative analysis of the validity and operational feasibility of two methods.

Abstract

BACKGROUND: Many health programs can assess coverage using standardized cluster survey methods, but estimating the coverage of nutrition programs presents a special challenge due to low disease prevalence.

Auteurs: Isanaka S Hedt-Gauthier BL Grais RF Allen BGS
Référence de l'article: Population health metrics 2018 07 03; 16(1); 11. doi: 10.1186/s12963-018-0167-3. Epub 2018 07 03
Bayesian conjugate analysis Cluster survey Coverage SQUEAC Severe acute malnutrition Therapeutic feeding program
ENG

Is 6 months of bedaquiline enough? Results from the compassionate use of bedaquiline in Armenia and Georgia.

Abstract

BACKGROUND AND SETTING: Bedaquiline (BDQ) was initially only available through compassionate use programmes.

Auteurs: Hewison C Bastard M Khachatryan N Kotrikadze T Hayrapetyan A Avaliani Z Kiria N Yegiazaryan L Chumburidze N Kirakosyan O Atshemyan H Qayyum S Lachenal N Varaine F Huerga H
Référence de l'article: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2018 Jul 01; 22(7); 766-772. doi: 10.5588/ijtld.17.0840. Epub 2018 06 19
ENG

Sub-national variation in measles vaccine coverage and outbreak risk: a case study from a 2010 outbreak in Malawi.

Abstract

BACKGROUND: Despite progress towards increasing global vaccination coverage, measles continues to be one of the leading, preventable causes of death among children worldwide.

Auteurs: Kundrick A Huang Z Carran S Kagoli M Grais RF Hurtado N Ferrari M
Référence de l'article: BMC public health 2018 Jun 15; 18(1); 741. doi: 10.1186/s12889-018-5628-x. Epub 2018 06 15
Equity Measles Outbreak Vaccination
ENG

Safety of a heat-stable rotavirus vaccine among children in Niger: Data from a phase 3, randomized, double-blind, placebo-controlled trial.

Abstract

BACKGROUND: Rotavirus remains a major cause of diarrhea among children under 5 years of age. The efficacy of RotaSIIL, a pentavalent rotavirus vaccine, was shown in an event-driven trial in Niger.

Auteurs: Coldiron ME Guindo O Makarimi R Soumana I Matar Seck A Garba S Macher E Isanaka S Grais RF
Référence de l'article: Vaccine 2018 06 14; 36(25); 3674-3680. doi: 10.1016/j.vaccine.2018.05.023. Epub 2018 05 08
Adverse event Diarrhea Gastroenteritis Intussusception Niger Rotavirus infection Rotavirus vaccines Safety